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Pharmacology and Toxicology of Amphetamine and Related Designer Drugs

NIDA Research Monograph, Number 94 [Printed in 1989]

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Table of Contents


Structure-Activity Relationships of MDMA-Like Substances-----1
David E. Nichols and Robert Oberlender

Self-Injection in Baboons of Amphetamines and Related Designer Drugs-----30
CA. Sannerud, J.V. Brady, and R.R. Griffiths

Stimulus Properties of Hallucinogenic Phenalkylamines and Related Designer Drugs: Formulation of Structure-Activity Relationships-----43
Richard A. Glennon

Amphetamines: Aggressive and Social Behavior-----68
Klaus A. Miczek and Jennifer W. Tidey

Neurochemical Mechanisms Involved in Behavioral Effects of Amphetamines and Related Designer Drugs-----101
Lisa H. Gold, Mark A. Geyer, and George F. Koob

Neuronal Actions of Amphetamine in the Rat Brain-----127
Philip M. Groves, Lawrence J. Ryan, Marco Diana, Stephen J. Young, and Lisa J. Fisher

Methamphetamine and Related Drugs: Toxicity and Resulting Behavioral Changes in Response to Pharmacological Probes-----146
Lewis S. Seiden and Mark S. Kleven

Role of Dopamine in the Neurotoxicity Induced by Amphetamines and Related Designer Drugs-----161
James W. Gibb. Donna M. Stone, Michel Johnson, and Glen R. Hanson

Acute and Long-Term Neurochemical Effects of Methylenedioxymethamphetamine in the Rat-----179
Christopher J. Schmidt

Effects of MDMA and MDA on Brain Serotonin Neurons: Evidence from Neurochemical and Autoradiographic Studies-----196
Errol B. De Souza and George Battaglia

Characterization of Brain Interactions With Methylenedioxyamphetamine and Methylenedioxymethamphetamine-----223
Robert Zaczek, Stephen Hurt, Steven Culp, and Errol B. De Souza

Pharmacologic profile of Amphetamine Derivatives at Various Brain Recognition Sites: Selective Effects on Serotonergic Systems-----240
George Battaglia and Errol B. De Souza

Effects of Amphetamine Analogs on Central Nervous System Neuropeptide Systems-----259
Glen R. Hanson, Patricia Sonsalla, Anita Letter, Kalpana M. Merchant, Michel Johnson, Lloyd Bush, and James W. Gibb

Effects of Neurotoxic Amphetamines on Serotonergic Neurons: Immunocytochemical Studies-----270
Mark E. Molliver, Laura A. Mamounas, and Mary Ann Wilson

Studies of MDMA-Induced Neurotoxicity in Nonhuman Primates: A Basis for Evaluating Long-Term Effects in Humans-----306
George A. Ricaurte

Dose- and Time-Dependent Effects of Stimulants-----323
Everett H. Ellinwood, Jr., and Tong H. Lee

Recommendations for Future Research on Amphetamines and Related Designer Drugs-----341
Ray W. Fuller

List of NIDA Research Monographs-----358

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