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Biological Vulnerability to Drug Abuse

NIDA Research Monograph, Number 89 [Printed in 1988]

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Table of Contents

Genetic Vulnerability to Drug Abuse-----1
Roy W. Pickens and Dace S. Svikis

Influence of Genetic Factors on Drug-Reinforced Behavior in Animals-----9
Richard A. Meisch and Frank R. George

Family Pedigree Studies of Biological Vulnerability to Drug Dependence-----25
James R. Stabenau

The Twin Method in the Study of Vulnerability to Drug Abuse-----41
Roy W. Pickens and Dace S. Svikis

Etiologic Factors in Substance Abuse: An Adoption Study Perspective-----52
C. Robert Cloninger

The High-Risk Paradigm in Alcohol and Drug Abuse Research-----73
Ralph E. Tarter

Personality Factors in Drug Addiction-----87
James N. Butcher

Individual Differences in Drug Response-----93
James R. Wilson

The Role of Psychopathology in the Familial Transmission of Drug Abuse-----108
Bruce J. Rounsaville

Methodological Issues in Family, Adoption, and Twin Research-----120
Dace S. Svikis and Roy W. Pickens

Analytical Approaches to Twin and Family Data-----134
Matt McGue

Exploring Drug Abuse With Genetic Strategies: Cautionary Tales-----150
Irving I. Gottesman

Biological Vulnerability: Treatment Implications/Applications-----165
George E. Bigelow, Robert K. Brooner, Mary E. McCaul, and Dace S. Svikis

The Applications of Biological Vulnerability Research to Drug Abuse Prevention-----174
Edward Kaufman

List of NIDA Research Monographs-----181

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