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Strategies for Research on the Interactions of Drugs of Abuse

NIDA Research Monograph, Number 68 [Printed in 1986]

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Table of Contents

Introduction and Overview-----1
Monique C. Braude and Harold M. Ginzburg

Critical Factors in Studying Drug Interactions-----6
Martin W. Adler

Issues in the Assessment of Multiple Drug Use Among Drug Treatment Clients------15
Robert L. Hubbard; Robert M. Bray; S. Gall Craddock; Elizabeth R. Cavanaugh; William E. Schlenger; and J. Valley Rachal

Statistical Analysis of Drug Interactions-----41
Clifford L. Mitchell

Problems of Pharmacodynamlc Measurement Related to Psychoactive Drug Interactions in Humans-----65
Richard C. Frecker

Pharmacokinetic Mechanisms of Ethanol-Psychotropic Drug Interactions-----73
Domenic A. Ciraulo and Jamie Barnhill

Complex Interactions Between Drugs and Dietary Factors-----89
Elliot S. Vesell

Interactions of Cannabis With Other Drugs in Man-----110
Leo E. Hollister

Alcohol and Marijuana: Concordance of Use by Men and Women-----117
Jack H. Mendelson; Nancy K. Mello; and Barbara W. Lex

Cocaine and Other Drug Interactions: Strategy Considerations-----142
Reese T. Jones

Cigarette Smoking: Interactions With Alcohol, Opiates, and Marijuana-----154
Nancy K. Mello and Jack H. Mendelson

Drug Combinations in Pleasure and Pain-----181
Conan Kornetsky

Drug Interactions With Methadone in Humans-----193
Mary Jeanne Kreek

List of NIDA Research Monographs-----226

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