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Narcotic Antagonists: The Search for Long-Acting Preparations



NIDA Research Monograph, Number 4 [Printed in 1976]

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Table of Contents

Introduction-----1

Abstracts-----7

Development of Polylactic/Glycolic Acid Delivery Systems For Use in Treatment of Narcotic Addiction-----13
A.D. Schwope, D.L. Wise, J.F. Howes

Development of Injectable Microcapsules For Use in the Treatment of Narcotic Addiction-----19
C. Thies

Long-Acting Narcotic Antagonist Complexes-----21
A.P. Gray, W.J. Guardina

Sustained Release of Naltrexone From Glyceride Implants-----27
M.F. Sullivan, D.R. Kalkwarf

Use of Synthetic Polypeptides in the Preparation of Biodegradable Delivery Vehicles For Narcotic Antagonists-----33
K.R. Sidman, D.L. Arnold, W.D. Steber, L. Nelsen, F.E. Granchelli, P. Strong, S.G. Sheth

Development of Chronomers™ For Narcotic Antagonists-----39
R.C. Capozza, E.E. Schmitt, L.R. Sendelbeck

Testing of Drug Delivery Systems For Use in Treatment of Narcotic Addiction-----43
R.H. Reuning, L. Malspeis, S. Frank, R.E. Notari




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