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NIDA. (2013, December 26). Research suggests new genetic target to treat cocaine addiction. Retrieved from

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Science Spotlight

December 26, 2013

NIDA-funded research shows that a specific mutation in the CYFIP2 gene dramatically lowers responses to cocaine in a mouse model. The mutation appears to affect the CYFIP2 protein, a key player in processes underlying memory, learning, and habit formation.  This research provides a new target for research into potential medications to treat cocaine addiction.

Cocaine synapseCocaine synapse

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