Science Spotlight

December 26, 2013

NIDA-funded research shows that a specific mutation in the CYFIP2 gene dramatically lowers responses to cocaine in a mouse model. The mutation appears to affect the CYFIP2 protein, a key player in processes underlying memory, learning, and habit formation.  This research provides a new target for research into potential medications to treat cocaine addiction.

Cocaine synapseCocaine synapse

For a copy of the study abstract, go to https://www.sciencemag.org/content/342/6165/1508.short.

For more information, contact the NIDA press office at media@nida.nih.gov or 301-443-6245.

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