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NIDA. (2013, October 29). Medication to treat marijuana addiction may be on the horizon. Retrieved from

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Science Spotlight

October 29, 2013

Marijuana plantMarijuana plant

NIDA funded researchers report that kynurenic acid is a naturally occurring substance in the brain that can lessen the effects of THC in animal models of drug abuse and addiction. The acid acts by reducing the function of alpha-7-nicotinic acetylcholine receptors.

If effective in humans, this could lead to a medication for the treatment of marijuana addiction. There are currently no approved medications for treating marijuana addiction, estimated to occur in nine percent of users.

For a copy of the study, published online Oct 13, go to

For more information, contact the NIDA press office at or 301-443-6245.