September 2012
To block the effects of abused drugs, scientists recruit the immune system.

New vaccines that aim to promote recovery from cocaine and heroin abuse showed promise in animal testing. Both vaccines induced rats’ immune system to produce high titers of antibodies that inhibit the target drug from reaching the brain. The rats’ behaviors when given access to the target drug indicated that the vaccines reduced the reinforcing effects that, in recovering people, can cause lapses to turn into relapses.

July 2012

Fewer than 12 percent of adolescents who meet diagnostic criteria for prescription opioid abuse or dependence receive any treatment, according to an analysis of data from the 2005 to 2008 National Survey on Drug Use and Health. The most common reason the adolescents gave for not receiving treatment was their lack of perceived need for it.

July 2012

Intensive case management was more effective in increasing treatment engagement and reducing alcohol consumption among depressed participants than among those who were not depressed, according to a followup analysis of a substance abuse treatment study involving women on welfare.

July 2012

Soluble-film preparations of buprenorphine suppressed heroin abusers’ withdrawal symptoms with no serious side effects in a recent clinical trial. They dissolved more rapidly in the mouth than the pill form of the medication, providing faster relief.

July 2012

Ninety percent of privately funded substance abuse treatment programs in the United States offer cognitive behavioral therapy (CBT)...

July 2012
A multisite clinical trial lays groundwork for improving care for mothers and babies affected by opioid dependence.

Sublingual buprenorphine is a safe and effective alternative to methadone for treating opioid dependence during pregnancy, finds the Maternal Opioid Treatment: Human Experimental Research (MOTHER) study, a NIDA-supported clinical trial. Women who received either medication had similar pregnancy and birth outcomes, but infants born to women who received buprenorphine had milder symptoms of neonatal opioid withdrawal.

April 2012

Expanded use of antiretroviral therapy in British Columbia reduced the spread of HIV among injection drug users and others in the province.

April 2012

Women with post-traumatic stress disorder (PTSD) who abused drugs responded better to substance abuse treatment after their PTSD symptoms improved, according to a recent study, which also found that reductions in substance abuse did not ease PTSD severity

April 2012

Substance abuse counselors and clinical supervisors disclosed high job turnover rates in a survey of 27 treatment organizations.

December 2011
Exercises to strengthen working memory may have a place in treatment.

Researchers correlate stimulant abusers’ improved performance on a memory training exerc ise with reductions in delay discounting.

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