Cite this article

NIDA. (2011, September 7). The Different Angles of Addiction. Retrieved from

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Sara Bellum
September 7 2011
Illustration of a brain with lightning coming out of it.

You may think you know what addiction is—lots of people have many different opinions about addiction and different ways of defining it. Here are some myths you may have heard:

  • Getting over addiction to drugs is a choice.
  • In order for treatment to work, the person has to hit “rock bottom.”
  • People have to choose to get treatment or it won’t be effective, such as when a judge sends a person to a treatment facility instead of jail.

The truth is that addiction is a complex brain disease that scientists are still figuring out. For instance, one person may use a drug once or many times and nothing bad happens, while others may overdose with the first use. Some people use drugs regularly and never become addicted, while others try drugs once or twice and do become addicted. There is no way of knowing in advance how a person may react to these dangerous substances. Whether or how quickly addiction takes hold in individuals depends on many factors, including:

  • Genes: Research shows that some people’s genes may leave them more susceptible to addiction than other people’s.
  • Environment: Kids who are exposed to drug use in their families or neighborhoods are at greater risk of engaging in drug abuse themselves.
  • Age at first use: The younger a person uses drugs, the more vulnerable he or she is to addiction in adulthood. Since the brain continues to develop well into a person’s twenties, using drugs in the teen years can set a person up for later drug problems.

What scientists know for sure is that many drugs “turn on” the brain’s reward circuit, which is part of the limbic system. The person then learns to associate the drug with pleasure and starts to crave it more and more, leading to compulsive drug use and often to addiction. In an addicted person, the brain changes in ways that cause compulsive drug seeking and use, despite negative consequences, so even if they want to quit, they can’t without treatment and support. That’s why addiction is considered a brain disease. Other activities in life also activate the brain’s reward circuit and can cause “driven” behaviors, such as compulsive overeating or video game playing. However, scientists are still trying to figure out why this happens in non-drug contexts—it may be connected to dopamine levels in the brain. Learn more about the science behind drug addiction by visiting