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Biological Mechanisms and Perinatal Exposure to Drugs



NIDA Research Monograph, Number 158 [Printed in 1995]

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Table of Contents

Preface -----1
Pushpa V. Thadani

Species-, Gender-, and Pregnancy-Related Differences in the Pharmacokinetics and Pharmacodynamics of Cocaine-----2
Hisayo O. Morishima and Robert A. Whittington

Effects of Morphine and Cocaine on Breathing Control in Neonatal Animals: A Minireview-----22
George D. Olsen and Laine J. Murphey

Cardiovascular Effects of Cocaine in Infant and Juvenile Piglets-----40
Frank M. Scalzo and Lora J. Burge

Effects of Cocaine on Fetal Brain Metabolism and Behavioral State in the Sheep Model-----58
David J. Burchfield

Fetal Cerebral Vascular Effects of Cocaine Exposure-----67
Michael D. Schreiber

Effects of Prenatal Morphine and Cocaine on Postnatal Behaviors and Brain Neurotransmitters-----88
Ilona Vathy

Prenatal Cocaine Produces Biochemical and Functional Changes in Brain Serotonin Systems in Rat Progeny-----115
George Battaglia, Theresa M. Cabrera, and Louis D. Van de Kar

Ontogeny of Methamphetamine-Induced Neurotoxicity in the Rat Model-----149
Charles V. Vorhees and Cunfeng Pu

Ontogeny of Nociception and Antinociception-----172
Gordon A. Barr

Perinatal Benzodiazepine Modulation of GABAA Receptor Function: Influence on Adaptive Responses-----202
Carol K. Kellogg




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