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Hallucinogens: An Update



NIDA Research Monograph, Number 146 [Printed in 1994]

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Table of Contents

Preface-----1
Geraline C. Lin

Classical Hallucinogens: An Introductory Overview-----4
Richard A. Glennon

Are Hallucinogens Psychoheuristic?-----33
Stephen Szára

Lysergamides Revisited-----52
Robert C. Pfaff, Xuemei Huang, Danuta Marona-Lewicka, Robert Oberlender, and David E. Nichols

Structure-Activity Relationships of Classic Hallucinogens and their Analogs-----74
Peyton Jacob III and Alexander T. Shulgin

Human Hallucinogenic Drug Research: Regulatory, Clinical, and Scientific Issues-----92
Rick J. Strassman

Serotonin Receptor Involvement in an Animal Model of the Acute Effects of Hallucinogens-----124
Mark A. Geyer and Kirsten M. Krebs

The Stimulus Effects of Serotonergic Hallucinogens in Animals-----157
Jerrold C. Winter

Electrophysiological Studies on the Actions of Hallucinogenic Drugs at 5-HT2 Receptors in Rat Brain-----183
George K. Aghajanian

Neurochemical Evidence That Hallucinogenic Drugs Are 5-HT1C Receptor Agonists: What Next?-----203
Elaine Sanders-Bush

Autoradiographic Approaches to Studying Hallucinogens or Other Drugs-----214
Nathan M. Appel

Hallucinogens Acting at 5-HT Receptors: Towards a Mechanistic Understanding at Atomic Resolution-----241
Harel Weinstein, Daqun Zhang, and Juan A. Ballesteros

Molecular Modeling of the Interaction of LSD and Other Hallucinogens with 5-HT2 Receptors-----263
Richard B. Westkaemper and Richard A. Glennon

Structure and Function of Serotonin 5-HT2 Receptors-----284
Jean C. Shih, Kevin Chen, and Timothy K. Gallaher

Summary-----298
Richard A. Glennon




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