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Peripheral Blockers as Treatments for Substance Abuse and Dependence

Program List


Click on title to see abstract, click on speaker's name to view biography


Monday, April 27, 1998
8:30 a.m. -
9:00 a.m.
Registration
9:00 a.m. -
9:05 a.m.
Opening Remarks Steven Sparenborg, Ph.D.
Medications Development Division
National Institute on Drug Abuse
9:05 a.m. -
9:15 a.m.
Welcome Richard A. Millstein, J.D.
Deputy Director,
National Institute on Drug Abuse
9:15 a.m. -
9:45 a.m.
Introductory Lecture: Immunological Approaches to the Treatment of Drug Dependence: Lessons From the Past Charles R. Schuster, Ph.D.
Wayne State University
9:45 a.m. -
10:15 a.m.
Keynote Address: Rational Design and Development of Protein-Based Therapies for Drug Abuse S. Michael Owens, Ph.D.
University of Arkansas for Medical Sciences
Cocaine Catalytic Antibodies Session
Chair, Jamie Biswas, Ph.D.
Medications Development Division
National Institute on Drug Abuse
10:15 a.m. -
10:45 a.m.
Anti-Cocaine Catalytic Antibodies Donald W. Landry, M.D., Ph.D.
Columbia University College of Physicians and Surgeons
10:45 a.m. -
11:00 a.m.
Break
11:00 a.m. -
11:30 a.m.
The Effects of Anti-Cocaine Antibodies on Cardiovascular, Locomotor, Reinforcing, and Lethal Effects of Cocaine in Rodents Gail D. Winger, Ph.D.
University of Michigan
11:30 a.m. -
12:00 p.m.
Development of Catalytic Antibodies for Cocaine John Cashman, Ph.D.
Human BioMolecular Research Institute
12:00 p.m. -
1:15 p.m.
Lunch (on your own)
1:15 p.m. -
1:45 p.m.
Basics of Antibody Catalysis Kim D. Janda, Ph.D.
The Scripps Research Institute
1:45 p.m. -
2:15 p.m.
Discussion
Antibodies Session I
Chair, Richard Hawks, Ph.D.
Medications Development Division
National Institute on Drug Abuse
2:15 p.m. -
2:30 p.m.
A Little Chemistry and Molecular Biology in Regards to Immunopharmacological Protocols in the Abatement of Cocaine Abuse and Addiction Kim D. Janda, Ph.D.
The Scripps Research Institute
2:30 p.m. -
3:00 p.m.
Immunization as a Therapeutic Strategy Against Cocaine Abuse M. Rocio A. Carrera
The Scripps Research Institute
3:00 p.m. -
3:15 p.m.
Break
3:15 p.m. -
3:45 p.m.
Therapeutic Vaccine for the Treatment of Cocaine Addiction Barbara S. Fox, Ph.D.
ImmuLogic Pharmaceutical Corporation
3:45 p.m. -
4:15 p.m.
Evaluation of Anti-Cocaine Antibodies and a Cocaine Vaccine in a Rat Self-Administration Model Kathleen M. Kantak, Ph.D.
Boston University
4:15 p.m. -
4:45 p.m.
Towards a Passive Immunotherapy for Cocaine Addiction Andrew B. Norman, Ph.D.
University of Cincinnati School of Medicine
4:45 p.m. -
5:15 p.m.
Development of a Vaccine for Treatment of Nicotine Dependence Marion Kasaian, Ph.D.
ImmuLogic Pharmaceutical Corporation
5:15 p.m. -
5:45 p.m.
Discussion
5:45 p.m. Adjournment
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Tuesday, April 28, 1998
Antibodies Session II
Chair, David McCann, Ph.D.
Medications Development Division
National Institute on Drug Abuse
8:30 a.m. -
9:00 a.m.
Is a Cocaine Anti-Idiotypic Vaccine Feasible? Mariangela Segre, D.Sc.
University of Illinois
9:00 a.m. -
9:30 a.m.
Effects of Active Immunization on Nicotine Distribution in Rats Paul Pentel, M.D.
University of Minnesota
9:30 a.m. -
10:00 a.m.
Use of a Drug Class-Specific Monoclonal Fab to Treat Phencyclidine Abuse and Overdose In a Rat Model S. Michael Owens, Ph.D.
University of Arkansas for Medical Sciences
10:00 a.m. -
10:15 a.m.
Discussion
10:15 a.m. -
11:00 a.m.
Poster Presentations and Break
Enzyme Enhancements Session
Chair, Betty Tai, Ph.D.
Medications Development Division
National Institute on Drug Abuse
11:00 a.m. -
11:30 a.m.
Enhancing Cocaine Metabolism With Butyrylcholinesterase as an Approach to Cocaine Addiction Treatment David A. Gorelick, M.D., Ph.D.
National Institute on Drug Abuse
11:30 a.m. -
12:00 p.m.
Attenuation of Cocaine's Activity by Butyrylcholinesterase (BChE) Gilberto N. Carmona
National Institute on Drug Abuse
12:00 p.m. -
1:00 p.m.
Lunch (on your own)
1:00 p.m. -
1:30 p.m.
Effect of JTP-4819 on Cocaine Metabolism Kazuo Matsubara, M.D.
Asahikawa Medical College Hospital
1:30 p.m. -
2:00 p.m.
The Development of Xenobiotic Scavengers by Protein Engineering Clarence A. Broomfield, Ph.D.
U.S. Army Medical Research Institute of Chemical Defense
2:00 p.m. -
2:30 p.m.
An Improved Cocaine Hydrolase: The A328Y Mutant of Human Butyrylcholinesterase Is Fourfold More Efficient Oksana Lockridge, Ph.D.
University of Nebraska Medical Center
2:30 p.m. -
2:45 p.m.
Novel Cocaine Esterases John Cashman, Ph.D.
Human BioMolecular Research Institute
2:45 p.m. -
3:15 p.m.
Discussion
3:15 p.m. Closing and Adjournment

[Index]


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