| Monday, July 27 |
| Introduction |
| Welcome
Alan I. Leshner, Ph.D.
National Institute on Drug Abuse, NIH
Nancy J. Kaufman, R.N.
The Robert Wood Johnson Foundation |
| Co-Chair Remarks
Timothy P. Condon, Ph.D.
Jaylan S. Turkkan, Ph.D.
National Institute on Drug Abuse, NIH |
| Section I: History and Pharmacology |
| Introduction
Jack E. Henningfield, Ph.D.
Johns Hopkins School of Medicine & Pinney Associates
Slides |
| Nicotine Delivery Systems
John Slade, M.D.
Robert Wood Johnson Medical School
University of Medicine and Dentistry of New Jersey
Slides |
| Pharmacology of Nicotine
Jack E. Henningfield, Ph.D.
Johns Hopkins School of Medicine & Pinney Associates
Slides |
| Questions and Answers |
| |
| Section II: Nicotine-Individual Risk Factors for Initiation |
| Introduction
Richard R. Clayton, Ph.D.
Center for Prevention Research
University of Kentucky |
| Ethnicity, Gender and Risk Factors for Smoking Initiation
Robin Mermelstein, Ph.D.
Health Research and Policy Center
University of Illinois at Chicago
Slides |
| Child and Adolescent Psychopathology as Risk Factors for Tobacco Use
Robert J. McMahon, Ph.D.
Child Clinical Psychology Program
University of Washington
Slides |
| The Genetic Epidemiology of Smoking
Kenneth S. Kendler, M.D.
Medical College of Virginia
Virginia Commonwealth University
Slides |
| Nicotine Metabolism Variability and Nicotine Addiction
Karen Ahijevych, Ph.D.
College of Nursing
Ohio State University
Slides |
| A Common Genetic Defect in Nicotine Metabolism Decreases Smoking
Rachel Tyndale, Ph.D.
Department of Pharmacology
University of Toronto
Slides |
| Discussion
Moon S. Chen, Jr., Ph.D., M.P.H.
School of Public Health
Ohio State University |
| Discussion
Gary E. Swan, Ph.D.
Center for Health Sciences
SRI International
Slides |
| Questions and Answers |
| |
| Keynote Address |
| Introduction of Keynote Address
Alan I. Leshner, Ph.D.
National Institute on Drug Abuse, NIH
Harold E. Varmus, M.D.
Director, National Institutes of Health |
| Keynote Address
Vice President Al Gore |
| Section III: Nicotine-Environmental Risk Factors for Initiation |
| Introduction
Nancy J. Kaufman, R.N., Chair
Robert Wood Johnson Foundation |
| Economics
Frank J. Chaloupka, Ph.D.
Department of Economics
University of Illinois at Chicago
Slides |
| Advertising and Promotion
John P. Pierce, Ph.D.
Cancer Prevention and Control Program
University of California at San Diego
Slides |
| Access to Tobacco
Nancy A. Rigotti, M.D.
Massachusetts General Hospital
Harvard Medical School
Slides |
| Effective Prevention Programs for Tobacco Use
Mary Ann Pentz, Ph.D.
Norris Cancer Center
University of Southern California |
| Discussion
Warren Bickel, Ph.D.
Human Behavioral Pharmacology Lab
University of Vermont
Slides |
| Discussion
Brian A. Flay, Ph.D.
School of Public Health
University of Illinois at Chicago
Slides |
| Questions and Answers |
| Closing Remarks
Alan I. Leshner, Ph.D.
National Institute on Drug Abuse, NIH |
|
| Tuesday, July 28 |
| Opening Remarks
Alan I. Leshner, Ph.D.
National Institute on Drug Abuse, NIH Jaylan S. Turkkan, Ph.D.
National Institute on Drug Abuse, NIH |
| Section IV: Biology of Nicotine Addiction |
| Introduction
Neil E. Grunberg, Ph.D.
Department of Medical and Clinical Psychology
Uniformed Services University of the Health Sciences |
| Neuropharmacology and Biology of Neuronal Nicotinic Receptors
Kenneth S. Kellar, Ph.D.
Department of Pharmacology
Georgetown University School of Medicine
Slides |
| Molecular Biology and Knockouts of Nicotinic Receptors
Marina Picciotto, Ph.D.
Department of Psychiatry
Yale University School of Medicine
Slides |
| Brain Chemistry and Imaging
Nora D. Volkow, M.D.
Medical Department
Brookhaven National Laboratory
Slides |
| Nicotine Reinforcement in Animals and Humans
Kenneth A. Perkins, Ph.D.
Western Psychiatric Institute and Clinic
University of Pittsburgh Medical Center
Slides |
| Discussion
William A. Corrigall, Ph.D.
Biobehavioural Research Department
Addiction Research Foundation
Slides |
| Questions and Answers |
| |
| Section V: Psychobiology of Nicotine Addiction |
| Introduction
Neil E. Grunberg, Ph.D.
Department of Medical and Clinical Psychology
Uniformed Services University of the Health Sciences |
| Behavior/Cognitive Effects of Smoking
Stephen Heishman, Ph.D.
Intramural Research Program
National Institute on Drug Abuse, NIH
Slides |
| Comorbidity and Smoking
John Hughes, M.D.
Department of Psychiatry, Psychology & Family Practice
University of Vermont
Slides |
| Individual Differences in Smoking and Nicotine Addiction
Saul Shiffman, Ph.D.
Department of Psychology
University of Pittsburgh
Slides |
| Discussion
M. Marlyne Kilbey, Ph.D.
Department of Psychology
Wayne State University
Slides |
| Discussion
Neal L. Benowitz, M.D.
Division of Clinical Pharmacology and Experimental Therapeutics
University of California at San Francisco
Slides |
| Questions and Answers |
| |
| Section VI: Treatment of Nicotine Dependence |
| Introduction
John Hughes, M.D.
Department of Psychiatry, Psychology & Family Practice
University of Vermont |
| Psychological Interventions
Sharon M. Hall, Ph.D.
Department of Psychiatry
University of California at San Francisco
Slides |
| New Medications for Nicotine Dependence Treatment
Richard D. Hurt, M.D.
Nicotine Dependence Center
Mayo Clinic
Slides |
| Combined Treatments
Maxine L. Stitzer, Ph.D.
Bayview Medical Center
Johns Hopkins University School of Medicine
Slides |
| Primary Care Based Interventions
Judith K. Ockene, Ph.D., M.Ed.
Division of Preventive and Behavioral Medicine
University of Massachusetts Medical Center
Slides |
| Treatment of Special Populations
Dorothy Hatsukami, Ph.D.
Department of Psychiatry
University of Minnesota
Slides |
| Interventions for Treatment Resistant Smokers
Karl Olav Fagerstrom, Ph.D.
Fagerstrom Consulting
Slides |
| Discussion
Paul M. Cinciripini, Ph.D.
M.D. Anderson Cancer Center
University of Texas
Slides |
| Discussion
Jasjit S. Ahluwalia, M.D., M.P.H., M.S.
Department of Preventive Medicine
University of Kansas Medical Center |
| Questions and Answers |
| Conference Overview |
| Conclusion: Nicotine Addiction
David B. Abrams, Ph.D.
Miriam Hospital
Brown University School of Medicine
Slides |
| Closing Remarks
Alan I. Leshner, Ph.D.
National Institute on Drug Abuse, NIH |