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Workshop on Clinical Consequences of Marijuana

August 1314, 2001
Neuroscience Center, Conference Room C
6001 Executive Boulevard
Rockville, Maryland

Presented by
Center on AIDS and Other Medical Consequences of Drug Abuse
Division of Neuroscience and Behavioral Research
National Institute on Drug Abuse
National Institutes of Health


Agenda (Click on titles to view abstracts)

Monday, August 13, 2001

8:15 a.m. - 8:30 a.m. Registration and Breakfast
8:30 a.m. - 8:45 a.m. Welcome
Jag H. Khalsa, Ph.D., Health Scientist Administrator, Center on AIDS and Other Medical Consequences of Drug Abuse (CAMCODA), National Institute on Drug Abuse (NIDA)

Rao S. Rapaka, Ph.D., Chief, Chemistry and Physiological Systems Research Branch, Division of Neuroscience and Behavioral Research, NIDA

8:45 a.m. - 9:00 a.m. Introduction
Sander G. Genser, M.D., M.P.H., Head, Medical Consequences Unit, CAMCODA, NIDA

Henry L. Francis, M.D., Director, CAMCODA

9:00 a.m. - 9:15 a.m. Opening Remarks
Alan I. Leshner, Ph.D.. Director, NIDA

Marijuana and Health (General)

9:15 a.m. - 9:20 a.m. Introduction
Billy R. Martin, Ph.D., Louis and Ruth Harris Professor and Chair, Department of Pharmacology and Toxicology, Virginia Commonwealth University
9:20 a.m. - 9:50 a.m. Role of Cannabinoid Receptors in Health
Raphael Mechoulam, M.Sc., Ph.D., Professor, Hebrew University, Jerusalem, Israel

Central Nervous System
Chair: Raphael Mechoulam, M.Sc., Ph.D., Professor, Hebrew University

9:50 a.m. - 10:20 a.m. Marijuana Withdrawal Syndrome in the Animal Model
Billy R. Martin, Ph.D., Louis and Ruth Harris Professor and Chair, Department of Pharmacology and Toxicology, Virginia Commonwealth University
10:20 a.m. - 10:50 a.m. Long-Term Neurocognitive Consequences of Marijuana: A Meta-Analytic Study
Igor Grant, M.D., Professor and Executive Vice Chair, Department of Psychiatry, University of California, San Diego
10:50 a.m. - 11:00 a.m. Break
11:00 a.m. - 11:15 a.m. Neuropsychological Performance in Long-Term Cannabis Users
Harrison G. Pope, Jr., M.D., Professor of Psychiatry, Harvard Medical School
11:15 a.m. - 11:30 a.m. Discussion
12:00 noon - 1:00 p.m. Lunch (on your own)

Cardiopulmonary-Respiratory Consequences of Marijuana
Co-Chair: Reese T. Jones, M.D., Professor of Psychiatry, University of California, San Francisco (UCSF)
Co-Chair: Donald P. Tashkin, M.D., Professor of Medicine, Pulmonary and Critical Care Division, University of California, Los Angeles (UCLA)

1:00 p.m. - 1:30 p.m. Pulmonary/Respiratory Consequences of Marijuana
Donald P. Tashkin, M.D., Professor of Medicine, Pulmonary and Critical Care Division, UCLA
1:30 p.m. - 1:45 p.m. Marijuana Use and Increased Risk of Squamous Cell Carcinoma of the Head and Neck
Zuo-Feng Zhang, M.D., Ph.D., Professor of Epidemiology and Director, Cancer Epidemiology Training Program, UCLA
1:45 p.m. - 2:15 p.m. Marijuana Use Is Not Associated With Head, Neck, or Lung Cancer in Adults Younger Than 55 Years: Results of a Case Cohort Study
Daniel E. Ford, M.D., M.P.H., Associate Professor of Medicine, Epidemiology and Health Policy and Management, Johns Hopkins University School of Medicine
2:15 p.m. - 2:45 p.m. Ongoing Case-Control Study of Marijuana Use and Cancer
Hal Morgenstern, Ph.D., Professor of Epidemiology, UCLA
2:45 p.m. - 3:00 p.m. Discussion
3:00 p.m. - 3:15 p.m. Break
3:15 p.m. - 3:45 p.m. Cardiovascular Effects of Marijuana: A Review
Reese T. Jones, M.D., Professor of Psychiatry, UCSF
3:45 p.m. - 4:15 p.m. Cardiovascular and Medical Complications of Marijuana: A Retrospective Cohort Study
Arthur L. Klatsky, M.D., Senior Consultant in Cardiology, Kaiser Permanente Medical Center

Endocrine/Reproductive and Developmental Effects of Marijuana

Co-Chair: Adrian S. Dobs, M.D., M.H.S., Professor of Medicine and Oncology, Johns Hopkins University
Co-Chair: Peter Fried, Ph.D., Professor, Carleton University, Ottawa, Canada
4:15 p.m. - 4:45 p.m. Endocrine Effects of Marijuana
Adrian S. Dobs, M.D., M.H.S., Professor of Medicine and Oncology, Johns Hopkins University
4:45 p.m. - 5:15 p.m. Aberrant Ligand-Receptor Signaling With Cannabinoids Affects Preimplantation Embryo Development and Implantation
Sudhansu K. Dey, Ph.D., University Distinguished Professor, Department of Molecular and Integrative Physiology, University of Kansas Medical Center
5:15 p.m. - 5:30 p.m. Discussion/Summary of the First Day

Tuesday August 14, 2001

8:15 a.m. - 8:30 a.m. Registration and Breakfast
8:30 a.m. - 9:00 a.m. Reproductive Effects of Marijuana: Sperm Fertility
Herbert Schuel, Ph.D., Professor of Anatomy and Cell Biology, State University of New York, Buffalo
9:00 a.m. - 9:30 a.m. Developmental Effects of Prenatal Exposure to Marijuana
Peter Fried, Ph.D., Professor of Psychology, Carleton University

Immune System, Infections (HIV), and Marijuana
Chair: Donald I. Abrams, M.D., Professor of Clinical Medicine, UCSF

9:30 a.m. - 10:00 a.m. Immune Function in Marijuana Smokers
Michael D. Roth, M.D., Professor of Pulmonary and Critical Care Medicine, UCLA
10:00 a.m. - 10:30 a.m. Marijuana and Immune Function in HIV/AIDS Patients
Donald I. Abrams, M.D., Professor of Clinical Medicine, UCSF
10:30 a.m. - 11:00 a.m. Consequences of Smoked Marijuana in Healthy and HIV-Infected Marijuana Smokers
Margaret Haney, Ph.D., Assistant Professor of Clinical Behavioral Biology, Columbia University
11:00 a.m. - 11:15 a.m. Discussion
11:15 a.m. - 11:30 a.m. Break

Treatment for Marijuana Complications

11:30 a.m. - 12:00 noon Behavioral Consequences of Marijuana Dependence
Alan J. Budney, Ph.D., Associate Professor of Psychiatry and Psychology, University of Vermont
12:00 noon - 12:15 p.m. Discussion
12:15 p.m. - 1:15 p.m. Lunch
1:15 p.m. - 3:00 p.m. Breakout Sessions

Group I (CNS and Cardiopulmonary Consequences) Open Discussion
Moderators: Billy R. Martin, Ph.D., and Donald P. Tashkin, M.D.

Group II (Endocrine, Reproductive, and Immune Systems) Open Discussion
Moderators: Peter Fried, Ph.D., and Donald I. Abrams, M.D.

3:00 p.m. - 4:00 p.m. Roundtable/Open Panel Discussion and Recommendations for Future Research
Moderator: Billy R. Martin, Ph.D.
4:00 p.m. Adjournment

 

[Introduction] [Abstracts] [Recommendations for Future Research] [Participant List]

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