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Foundations and Innovations in the Neuroscience of Addiction



Dedicated to the memory of Dr. Roger Brown, Associate Director of Neuroscience and Behavioral Research at the National Institute on Drug Abuse

A Two-Day Symposium, May 14-15, 2003
William H. Natcher Conference Center, NIH Campus
8:30 a.m. - 5:30 p.m.


Agenda

Wednesday, May 14, 2003

8:30 - 9:00 a.m. Registration
9:00 - 9:15 a.m. Introduction
Nora D. Volkow, M.D.
Director
National Institute on Drug Abuse
9:15 - 10:15 a.m. Specificity of Dopamine's Actions on Working Memory Circuitry
Patricia S. Goldman-Rakic, Ph.D. - Keynote Speaker
Yale University School of Medicine
10:15 - 10:45 a.m. Building Neural Representations of Habits
Ann M. Graybiel, Ph.D.
Massachusetts Institute of Technology
10:45 - 11:15 a.m. Break
11:15 - 11:45 a.m. Descending Modulation of Pain
Gerald F. Gebhart, Ph.D.
University of Iowa
11:45 a.m. - 12:15 p.m. Brain-Stimulation Reward, Morphine-Induced Oral Stereotypy, and Sensitization: Implications for Abuse
Conan Kornetsky, Ph.D.*
Boston University School of Medicine
12:15 - 1:30 p.m. Lunch On Own
1:30 - 2:00 p.m. Brain Reward Circuitry and Addiction
Roy A. Wise, Ph.D.*
National Institute on Drug Abuse
2:00 - 2:30 p.m. Social Experiences: Amines and Peptides in the Mesocorticolimbic System
Klaus A. Miczek, Ph.D.
Tufts University
2:30 - 3:00 p.m. Modeling the Addiction Process With Binge-Abstinence Patterns of Cocaine Self-Administration
David C.S. Roberts, Ph.D.
Wake Forest University School of Medicine
3:00 - 3:30 p.m. Break
3:30 - 4:00 p.m. Opponent-Process Properties of Self-Administered Cocaine
Aaron Ettenberg, Ph.D.
University of California, Santa Barbara
4:00 - 4:30 p.m. Cortico-Limbic-Striatal Circuitry and Reward Mechanisms: Insights for Addiction
Ann E. Kelley, Ph.D.
University of Wisconsin
4:30 - 5:00 p.m. Involvement of Cholinergic Neuronal Systems in Rodent Drug Self-Administration
James E. Smith, Ph.D.
Wake Forest University School of Medicine
5:00 - 5:30 p.m. Adaptations to Chronic Cocaine Exposure in a Nonhuman Primate Model
Linda J. Porrino, Ph.D.
Wake Forest University School of Medicine
5:30 p.m. Adjourn for the Day

Thursday, May 15, 2003

9:00 - 9:30 a.m. Neural Mechanisms of Opioid Analgesia
Howard L. Fields, M.D., Ph.D.*
University of California, San Francisco
9:30 - 10:00 a.m. Memory, Reward, and Substance Abuse
Sam A. Deadwyler, Ph.D.
Wake Forest University Health Sciences
10:00 - 10:30 a.m. Cocaine Effects on the Developing Brain: Current Status
John A. Harvey, Ph.D.
Drexel University College of Medicine
10:30 - 11:00 a.m. Break
11:00 - 11:30 a.m. Why Is Cocaine so Reinforcing?
Nora D. Volkow, M.D.
National Institute on Drug Abuse
11:30 -12:00 p.m. The Role of Basic Research in NIDA's Medications Development Program
Francis Vocci, Ph.D.
National Institute on Drug Abuse
12:00 - 1:15 p.m. Lunch On Own
1:15 - 1:45 p.m. Amphetamine Neurotoxicity Research: Accomplishments and Remaining Challenges
George A. Ricaurte, M.D., Ph.D.
Johns Hopkins Bayview Medical Center
1:45 - 2:15 p.m. LSD, Serotonin (5-HT), and the Evolution of a Behavioral Assay
James B. Appel, Ph.D.*
University of South Carolina
2:15 - 2:45 p.m. Neurobiological Mechanisms in the Transition From Drug Use to Drug Dependence
George F. Koob, Ph.D.
Scripps Research Institute
2:45 - 3:15 p.m. Break
3:15 - 3:45 p.m. Neurochemical and Behavioral Studies on Ethanol and Nicotine Interactions
Jörgen A. Engel, M.D., Ph.D.
Göteborg University
3:45 - 4:15 p.m. Sensitization of Midbrain Dopamine Neuron Reactivity and the Self-Administration of Psychomotor Stimulant Drugs
Paul Vezina, Ph.D.
University of Chicago
4:15 - 4:45 p.m. Drug Abuse Genetics: Monoamines and Beyond
George R. Uhl, M.D., Ph.D.
National Institute on Drug Abuse
4:45 p.m. Adjournment

* These speakers have been asked to provide an overview or special perspective of this research.


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