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National Institute on Drug Abuse

Director's Report to the National Advisory Council on Drug Abuse

September, 1996


Meetings/Conferences


NIDA co-sponsored the Conference On Drug Abuse (CODA) with the American Psychological Association, Science Directorate, as a satellite conference to APA's 104th Convention in Toronto, Ontario, August 9-13, 1996. The goal of CODA was to highlight the best in drug abuse and addiction research. The conference included approximately 100 coordinated drug abuse research activities including a special address by Dr. Alan Leshner, 16 keynote speeches, 5 continuing education training workshops, a reception, several grant application training workshops, program initiative workshops and other special programs as well as drug abuse symposia, paper, and poster sessions. The CODA Steering Committee worked with a contractor to develop a colorful site on the NIDA homepage. The site served as a useful tool for sharing information about the August Conference. A link was also created to the APA home page.

NIDA's Office of Science Policy and Communications organized a "Town Meeting"
co-sponsored by NIDA and the Ohio Department of Alcohol and Drug Addiction Services, "Strengthening Communities Through Prevention," in Columbus, on May 9, 1996. The meeting brought together local and state policy makers and professionals in the alcohol and drug abuse field to learn about effective, community-based prevention strategies/models from leading researchers.

On June 27-28, 1996 a CPDD satellite meeting on the "Use, Abuse, and Sequelae of Methamphetamine Abuse with Implications for Prevention, Treatment and Research" was held in San Juan, Puerto Rico. The meeting was sponsored by SAMHSA in collaboration with NIDA. Dr. Jerry Frankenheim, DBR and Dr. Dorynne Czechowicz, DCSR, presented information on NIDA's current portfolio of methamphetamine research. Dr. Frank Vocci, Acting Director, MDD, presented on medication development for psychostimulant abuse. NIDA funded grantees presented on the epidemiology of methamphetamine abuse and implications for prevention approaches; basic pharmacology and mechanisms of action; medical complications; treatment and prevention research. The NIDA representatives also participated in workgroup discussions of Basic Pharmacology and Mechanisms of Action; Medical complications and Management; and Treatment and Prevention. A report of the meeting, including the workgroup discussions, is being prepared by Dr. Scott Lucas, the methamphetamine meeting Chair.

A Hispanic Research Conference sponsored by NIDA was held as a satellite meeting at CPDD on June 21-22, 1996 in Puerto Rico. Presentations included sessions on patterns of drug abuse for Mexican-Americans and Puerto Ricans, recruiting and retaining Hispanic subjects in drug abuse and AIDS research, drug treatment careers among Hispanic populations, and social support and drug use.

NIDA's Hispanic Work Group met on June 20, 1996 in Puerto Rico. A highlight of the meeting was a panel presentation by young researchers who discussed the obstacles and supports encountered in developing research careers.

NIDA's Special Populations Office and the State University of New York at Old Westbury sponsored a Special Populations Research Development Workshop on "Morphine and Nitric Oxide" in Melville, L.I., NY on June 5-7, 1996. Approximately 20 faculty and trainee attendees took part in lectures and hands-on demonstrations of various imaging processing and analyses of nitric oxide, including computer-assisted microscopy, and learned about applications of these techniques in biomedical research.

NIDA's Special Populations Office sponsored a panel at the National Medical Association's Convention in Chicago on July 30, 1996. The panel focused on drug abuse in physicians.

NIDA's African American Researchers and Scholars Meeting was held in New Orleans on July 28, 1996. Participants discussed improving drug abuse research in African American communities, and on increasing involvement by African American and other ethnic minority researchers in research supported by NIDA and NIH.

A NIDA- and ORMH-supported conference on "Creating Partnerships and Collaborations between Minority Populations Researchers, Community-Based Drug Abuse Treatment and Research Programs" was held July 29-August 1, 1996 in New Orleans, LA. About 200 participants attended plenaries, workshops, and poster sessions on community-based research, collaboration between researchers, research institutions and community-based organizations, and technical assistance sessions on developing competitive research proposals.

NIDA's Special Populations Office cosponsored the American Psychological Association's "Diversity Project 2000 Summer Institute 1996" in Toronto on August 7-10, 1996. Twenty-five ethnic minority students from U.S. community colleges and their faculty sponsors attended this mentoring and leadership building program, which oriented students to career and higher education opportunities in psychology. As part of the Institute, NIDA presented a one-day program which focused on NIDA and NIH research programs, careers in psychology, and preparation for careers in drug abuse research.

NIDA's Services Research Branch sponsored a health services research seminar, "Financing and Costs of Drug Treatment," June 19 in the Parklawn Building. The seminar included presentations by NIDA-funded investigators Drs. Richard Frank, Constance Horgan, Dennis McCarty, and Michael French. Dr. Cartwright of the Services Research Branch chaired the session and presented a paper entitled "Drug Abuse Treatment Costs: Findings from a New Methodology".

On September 8-14 and in collaboration with the University of Miami, NIDA sponsored a workshop entitled "Andean Region Drug Abuse Epidemiology Methods and Research Development" in Miami, Florida. The workshop was co-chaired by Mario De La Rosa, Ph.D., of the Office of Special Populations, Moira O'Brien of DEPR, and J. Bryan Page, Ph.D., of the University of Miami. NIDA Deputy Director Richard A. Millstein, who had met with members of the planning committee last year in Rockville, gave the opening address to the researchers from Colombia, Venezuela, Peru, Ecuador, Bolivia, and Chile.

Robert Heimer, Ph.D., of Yale University was invited by NIDA, under the auspices of CRB/DEPR and the Office on AIDS, to present a lecture entitled "New Rigs for Old: Virologic and Molecular Epidemiologic Underpinnings of Needle/Syringe Exchange," held on the NIH campus on June 19. Dr. Heimer described his evaluation research to determine the effects of New Haven's Needle Exchange Program (NEP) on the spread of HIV. Using polymerase chain reaction and EIA, he and colleagues have demonstrated that the New Haven NEP has slowed the spread of HIV among IDUs by at least one third. Dr. Heimer also described their current work to elaborate the unobtrusive needle testing and syringe tracking methods used to assess NEP effects on the spread of HIV in order to determine transmission patterns of acute and chronic hepatitis infections.

The Behavioral Sciences Research Branch held a Question and Answer Session on Training and Funding Opportunities in the Basic Behavioral Sciences of Drug Abuse at the College on Problems of Drug Dependence meeting in San Juan, Puerto Rico in June 1996.

Alan I. Leshner, Ph.D. and Dr. Timothy Condon co-chaired the first annual NIDA Training Directors Meeting in Rockville, MD, May 1, 1996. Forty-two of NIDA's forty-four training directors were able to attend. During the morning session, NIDA staff briefed the Training Director's on current trends, opportunities and policies. In the afternoon, participants broke into work groups and focused on evaluating current training strategies and developing creative responses to emerging trends in the field. NIDA Deputy Director Richard Millstein and NIDA's Division Directors also attended.

NIDA Deputy Director Richard A. Millstein presented at and moderated an all-day symposium on drug abuse research findings held June 1, 1996 in Honolulu, Hawaii as a pre-conference satellite to the 1996 NASADAD Annual Meeting. Attendees were nearly 50 state alcohol and drug abuse program directors and their staff and local Hawaiian scientists and legislators.

NIDA Deputy Director Richard A. Millstein presented historical context remarks at the 20th anniversary meeting of the National Institute on Drug Abuse Community Epidemiology Work Group, held in New York City June 4-7, 1996.

NIDA Deputy Director Richard A. Millstein presented a keynote address on findings from drug abuse prevention research at the Cornell University Medical College Institute for Prevention Research's Conference on Multi-Ethnic Drug Abuse Prevention Research Findings and Implications for Practice, June 6 - 7, 1996, in New York City.

NIDA Deputy Director Richard A. Millstein represented NIH Director Dr. Harold Varmus and NIDA Director Dr. Alan I. Leshner at the National Leadership Forum on Preventing Substance Abuse and HIV held August 14-16, 1996 in Tampa, Florida. The Forum responded to the request of President Clinton at the December 6, 1995 White House Meeting on AIDS that CDC "convene a meeting of state and local people involved in both public health and drug prevention to develop an action plan that integrates HIV prevention and substance abuse prevention." Federal sponsors in addition to CDC were SAMHSA, HRSA, the Office of National AIDS Policy, the Office of National Drug Control Policy, and NIDA/NIH. National organizations co-sponsoring the meeting included NASADAD, the Association of State and Territorial Health Officials, the National Alliance of State and Territorial AIDS Directors, Join Together, the Partnership for a Drug-Free America, the National Prevention League, and the Community Anti Drug Coalitions of America.

Dr. Steven Gust, Acting Director of NIDA's Office on AIDS presented an "Overview of HIV/AIDS Research at the NIDA, NIH" and presented a NIDA/OoA poster session at the June CPDD Conference held in San Juan Puerto Rico.

Dr. Gust held a training session on NIDA research grants and research training opportunities in the area of drug abuse-related HIV/AIDS in May at the University of Minnesota.

Ms. J.C. Comolli of NIDA's Office on AIDS attended a July 31 meeting at the Office of National Drug Control Policy (ONDCP) with representatives from the National Alliance of State and Territorial AIDS Directors (NASTAD), and staff from the Office on National AIDS Policy and the HHS Office of Planning and Evaluation. NASTAD requested the meeting to present findings from the States on ways to reduce the spread of infectious diseases related to drug use and to present areas of collaboration at the state and local level.

Dr. Lula Beatty, Director of NIDA's Special Populations Office, was a panelist discussing federal initiatives and opportunities in violence and drug abuse prevention at the annual convention of the Association of Black Psychologists in Chicago on August 2, 1996.

Dr. David Johnson, DBR, BNRB, represented NIDA at a meeting entitled "Exploring Alternatives to Abstinence for Nicotine Dependence" sponsored by the Robert Wood Johnson Foundation in Newark, NJ on May 23, 1996.

Dr. Tom Aigner, DBR, BNRB, represented NIDA at the XVI Congress of the International Primatological Society in Madison, WI on August 11-16, 1996.

Dr. Jaylan S.Turkkan, Chief of the Behavioral Sciences Research Branch, Division of Basic Research, chaired the Federal Funding Poster Session at the San Francisco annual meeting of the American Psychological Society (June 29- July 2, 1996).

Dr. Jaylan Turkkan and Dr. Timothy Condon held a breakfast roundtable entitled "Cents and Sensibility: How to Support Your Career in Drug Abuse Research" at the American Psychological Society Meeting in San Francisco in July, 1996. They discussed research training and early research career support opportunities such as fellowships, career development awards, and the newly initiated NIDA B/START program.

Dr. Jaylan Turkkan gave a presentation as discussant in a symposium entitled "Laboratory Models of Drug Abuse" at the American Psychological Association annual meeting in Toronto, Canada in August. She also chaired a lecture session given by Dr. Robert Balster entitled "Scientific Perspectives on Inhalant Abuse".

Dr. David Shurtleff chaired a lecture session at the American Psychological Association given by Dr. Thomas Coates "Drug Abuse and HIV Transmission: What's Needed to Protect the Next Generation".

Dr. Cora Lee Wetherington hosted a NIDA hospitality suite event at the American Psychological Association annual meeting in Toronto, Canada entitled "Drug Abuse, Women and Gender Differences: Research Opportunities at NIDA".

Dr. Lynda Erinoff co-chaired a symposium at the College on Problems of Drug Dependence entitled "Using Molecular Biological Tools to Explore Behavior".

Dr. Cora Lee Wetherington was a discussant in a symposium entitled "Drugs of Abuse and Gender Differences" at the College on Problems of Drug Dependence meeting in San Juan, Puerto Rico.

On May 13, Dr. Frank Vocci presented at a Loyola University of Chicago sponsored symposium entitled Cocaine and the Amphetamines: Effects on Brain and Behavior. The title of Dr. Vocci's presentation was: "Neurobiological Advances in the Pharmacology of Cocaine: Implications for Medications Development."

On May 18, Joel Egertson, Senior Advisor to the Director, Medications Development Division, gave a presentation entitled "Expanding Drug Abuse Treatment: We're All In This Together" at the Maryland Addictions Directors Council (MADC) Conference on "Coping with Change: Getting a Grip" in Ocean City MD. Mr. Egertson discussed the work of the NIDA medications development program, and the role of pharmacotherapy in drug abuse treatment in an environment of managed care and cost containment in health care.

On June 5, Dr. Peter Cohen presented a seminar (organized by MDD) with Mercedis Serabian, Ph.D., on "Regulatory and Ethical Issues in the Development of an Anti-Cocaine Vaccine."

On June 19-22, Dr. Peter Cohen participated in the Eighth Annual Bioethics Summer Retreat, Copper Mountain, Colorado. Discussions included: "Screening Pregnant Women and Babies for HIV Infection: Privacy and its Limits" and "Perinatal AIDS: Maternal/Fetal Conflict".

On June 24, Drs. James Hill and Frank Vocci co-chaired a workshop at the College on Problems of Drug Dependence meeting in San Juan, Puerto Rico. The purpose of the workshop was to illustrate new statistical methods used in the evaluation of urine testing for illicit drugs as an efficacy marker for potential pharmacotherapies. Dr. K.-Y. Liang of Johns Hopkins University spoke of his longitudinal analysis methods and their application to the evaluation of illicit drug use in urine data in clinical trials involving new medications.

On June 24, Dr. Peter Bridge of MDD served as a discussant at the CPDD session on Substance Abuse Medication Development and HIV Infection.

On June 27, Dr. Frank Vocci presented the approaches to development of a medications for cocaine dependence to a satellite meeting on methamphetamine abuse. The meeting was co sponsored by CSAT and CPDD.

On August 12, Dr. Frank Vocci served as a discussant at a session entitled, "Current Trends in the Pharmacotherapy of Opiate Abuse" at the American Psychological Association meeting in Toronto, Canada.

Dr. Joseph Frascella, Chief of the Etiology and Clinical Neurobiology Branch, Division of Clinical and Services Research served as a moderator for the oral research presentations at the recent meeting, "Building International Research in Drug Abuse: Opportunities and Challenges" at the CPDD meeting in San Juan, Puerto Rico, on June 22, 1996.

Dr. Frascella was a faculty participant in the "NIDA Special Populations Research Training Workshop on Morphine and Nitric Oxide" held in Melville, New York, June 5 - 7, 1996. He gave a seminar entitled "Neuroscience Research at NIDA" as well as a seminar entitled "Critical Aspects of the Grant Process."

Dr. Mac Horton of the Etiology and Clinical Neurobiology Branch, Division of Clinical and Services Research, presented a workshop on "Neuropsychology of Drug Abuse: Assessment, Residual Effects and Ecological Validity" to the Psychology Staff and interns at Crownsville State Hospital Center, Crownsville, Maryland, on May 17, 1996.

Dr. Horton attended the 104th American Psychological Association Annual Convention in Toronto, Canada, August 8-13, 1996 and chaired a Symposium on "Neurobiological and Neuropsychological Assessment of Drug Abuse", a Poster Session on "Applied Research on Addictions," and an Invited Address by George De Leon, Ph.D, on "Therapeutic Community: Advances in Research and Practice."

Dr. Harold Gordon presented a paper at the 104th American Psychological Association Annual Convention in Toronto, Canada, August 8-13, 1996 entitled, "Environmental and Biological Interactions: Etiologies of Drug Abuse and Violence," which summarized data by NIDA grantees and others suggesting some common biological and environmental factors underlying both drug abuse and violent behavior. Dr. Gordon also chaired an Invited Address by Jack Henningfield, Ph.D, of NIDA's Division of Intramural Research on "Public Policy Foundation: Up in Smoke--Nicotine Research Travails."

On July 10, 1996 Dr. Dorynne Czechowicz, TRB, DCSR represented NIDA at an Institute of Medicine Planning Workshop on Attention Deficit Hyperactivity Disorder: Issues of Definition, Diagnosis, and Management which was held at the National Academy of Sciences, Washington, D.C. Federal representatives from NIDA, NIMH, NICHD, and the Department of Education Office of Special Education Programs participated in discussions of Federal Interests and Research Priorities.

Drs. Elizabeth Rahdert and Lisa Onken of the Division of Clinical and Services Research participated in the Annual Convention of the American Psychological Association (APA), held August 9-13, 1996, in Toronto, Canada. Dr. Rahdert organized and participated in the continuing education (C.E.) workshop entitled "Adolescent Drug Abuse Treatment Strategies" and the NIDA Child and Adolescent Workgroup hospitality suite hour entitled "Research and Clinical Applications in Child and Adolescent Drug Abuse: Dialog and Resources." She also chaired the symposium "Assessment Associated with Adolescent Drug Abuse Treatment" and served as the discussant on the symposium "Recent Findings on Adolescent Drug Abuse and Protective Factors." Dr. Onken organized and chaired the C.E. workshop entitled "Drug Addiction Treatment: Clinical Applications of Recent Research Advances."

Mr. Thomas Vischi and Dr. William S. Cartwright assisted in the planning of the Secretary's national conference, "Access and Opportunity: A National Leadership Conference on Managed Behavioral Health Care," May 14 and 15, 1996, Arlington, VA.

Dr. Frank Tims chaired a NIDA symposium, "Managed Care Research and Institutional Change," in conjunction with the annual meeting of the Association for Health Services Research in Atlanta, August 9. The symposium presented research on the implementation and impact of financing drug treatment services through managed care arrangements. Dr. William Cartwright served as a discussant in that symposium.

Dr. Bennett Fletcher attended the American Psychological Association meeting in Toronto August 9-13. He presented two papers, "A Brief History of Treatment Outcome Research in the United States" and "Drug Abuse Treatment and Services: Reducing Violence in the Community" (co-authored with Dr. Peter Delany), and also served as a discussant in a symposium presenting recent NIDA-funded research on treating special populations in therapeutic communities.

Timothy P. Condon, Ph.D., NIDA's Associate Director for Science Policy, and Theresa Levitin, Ph.D., Deputy Director, OEPR co-chaired a Grant Writing Workshop for young researchers at the College on Problems of Drug Dependence annual meeting in San Juan, Puerto Rico, April 23, 1996. Participants saw a "mock IRG" review and received a resource guide of information, contacts and selected articles.

Dr. Timothy Condon was invited to address the American Psychological Society's (APS) Annual Board Meeting, June 29 1996, during APS's 8th Annual Convention in San Francisco, California, June 29-July 2, 1996. He discussed NIDA's research portfolio and research training efforts.

At the Conference On Drug Abuse in Toronto, August 12, 1996, Drs. Condon, Levitin, and Turkkan hosted a grant writing workshop. Dr. Condon also co-hosted a session entitled "Seeking NIDA Funding on the Neurobiological Basis of Drug-Related Behavior" with Dr. Harold Gordon, DEPR. In addition, Ms. Carolyn Mosher, OSPC hosted a workshop on "NIDA's Innovative Science Education Program".

Dr. Condon was invited to address the Annual Meeting of the American Academy of Child and Adolescent Psychiatry's (AACAP) standing Research Workgroup, on August 14, 1996, in Washington, D.C. He spoke about NIDA's research portfolio, research training, and efforts to recruit child and adolescent psychiatrists into drug abuse and addiction research.

Dr. Cora Lee Wetherington, NIDA's Women's Health Coordinator, co-chaired a session, "Drugs of Abuse and Gender Differences" at the annual CPDD meeting in San Juan. She also served as the discussant for the symposium.

Dr. Cora Lee Wetherington hosted a hospitality hour, "Drug Abuse, Women, and Gender Differences: Research Opportunities at NIDA" at the NIDA/APA organized Conference on Drug Abuse at the annual meeting of the American Psychological Association in Toronto.

Drs. Zili Sloboda, William Bukoski and Rebecca Ashery represented NIDA's Division of Epidemiology and Prevention Research at the Society for Prevention Research meeting held in San Juan, Puerto Rico. In conjunction with this meeting Dr. Ashery also held a small meeting with experts in the field to examine the issue of child monitoring for family prevention intervention.

At the NIDA/American Psychological Association Science Directorate co-sponsored Conference on Drug Abuse (Toronto, Ontario, August 9-13, 1996) Meyer Glantz, Ph.D. of DEPR chaired several sessions of etiology researchers to explore more formal efforts to integrate and facilitate the activities and community of etiology researchers. Several initiatives were proposed and these will be explored further and developed by NIDA's Resiliency and Risk/ Etiology Workgroup during the coming year. Included is an increased presence and involvement of etiology research in the activities and mission of the Society for Prevention Research.

Richard H. Needle, Ph.D., M.P.H., presented highlights from the research portfolio of the Community Research Branch, DEPR for the August 2, 1996 inaugural of the new location of the National Development and Research Institutes, Inc. in New York City. NDRI moved from Beach Street to the Two World Trade Center.


Richard H. Needle, Ph.D., M.P.H., appeared on a WORLDNET broadcast to Latin America on August 8 which focused on "Illegal Narcotics and AIDS: Ties that Bind." Dr. Needle, along with Dr. Larry Bruni, a Washington-area physician known for his work with HIV-positive patients, engaged in an interactive, question-and-answer discussion with overseas panelists from Peru, Ecuador, and Barbados. The WORLDNET Dialogue program was the seventh in a series on Narcotics Issues that have been produced by the U.S. Information Agency Television and Film Service. Prior programs have addressed the environmental impact of cocoa production, the economic impact of money laundering in Latin America, drug prevention programs for youth, and drug abuse prevention and treatment for the general population.

Dr. Richard H. Needle, Ph.D., M.P.H., gave a presentation on research priorities in community based prevention of the risk behaviors associated with drug abuse, HIV/AIDS, and other infectious diseases, at the Institute for Health Care Policy at Georgetown University Medical Center in Washington, D.C., on August 12.

Dr. Leslie Cooper, ERB/DEPR, recently served as the Co-Chair for the Healthy People 2000 Progress Report Sub-Workgroup for Priority Area 14 (Maternal and Infant Health) on Substance Abuse. She also served as an active member of the Healthy People 2000 Progress Review for the Black Americans Sub-Workgroups for both Research and Health Services.

Dr. Coryl Jones, ERB/DEPR, has participated in the steering committees for several national efforts focused on child abuse and on domestic violence. One of the results will be the National Conference on Child Abuse and Neglect to be held in Washington, DC, September 16-21, 1996. Another activity is the coordinating committee of agencies providing research support on child abuse and on domestic violence.

Mario De La Rosa, Ph.D., formerly with CRB/DEPR and now with NIDA's Office of Special Populations, gave two presentations at the NIDA-sponsored Hispanic Drug Abuse and AIDS Research Conference, held in conjunction with the annual meeting of the College on Problems of Drug Dependency in San Juan, Puerto Rico in June. One presentation was on "The Role of Social Support Systems in Drug Use Behavior of Hispanics," and the second was on "The State of Drug Abuse Research among Hispanics."

Susan Coyle, Ph.D., of CRB/DEPR represented NIDA at the American Sociological Association's 5th Annual Research Support Forum. The forum, held August 17-18 during ASA's annual meeting in New York City, included a poster session for participants to talk one-on-one with Federal program officials about research priorities, research grant application procedures, and specific areas of research interest and concern.

Peter Hartsock, Ph.D., served on the Advisory Committee for the National Council on International Health's Annual Conference in Washington, D.C., June 9-12. The theme of the conference was new and emerging infectious diseases (EREIDs). In recognition of the
increasing health threat and global importance of EREIDs, Vice President Albert Gore and DHHS Secretary Donna Shalala released a Presidential Decision Directive at the conference that pledged additional Federal support for new research in this area.

Mario De La Rosa, Ph.D., of NIDA's Office of Special Populations, gave a presentation on "Developing a Conceptual Model to Understand the Drug Use/Crime Relationship" at the American Psychological Association annual meeting in Toronto, Canada on August 11, 1996.

Dr. Edythe D. London, DIR, presented a paper entitled, "Cocaine-Related Cues Elicit Craving and Activate Cortical Circuits Relevant to Episodic Memory" at the 51st annual meeting of the Society of Biological Psychiatry, New York, NY, May 1-5, 1996.

Dr. Edythe D. London presented a lecture entitled, "Correlation of Cue-Elicited Cocaine Craving with Metabolic Activation in Prefrontal Cortex and Medial Temporal Lobe" at the annual meeting of the College on Problems of Drug Dependence, San Juan, PR, June 22-27, 1996.

Dr. Monique Ernst, DIR, presented papers entitled, "Influence of Sex and Age on Brain Glucose Metabolism in Control and ADHD Adults" and "Low Dopamine Activity in Lesch-Nyhan Disease. An 18F-fluorodopa PET Study" at the Annual Meeting of the Society for Nuclear Medicine, Denver, CO, June 1996.

Dr. Alexis Thompson, DIR, presented a paper entitled, "Evidence that Kappa-Opioid Agonists Induce Long-Term Alterations in Dopamine Uptake and Release" at the International Narcotics Research Conference, Long Beach, CA, July 21-26, 1996.

Dr. Alexis Thompson presented a paper entitled, "Interaction of Kappa-Opioid Agonists with Cocaine: Characterization by Quantitative Microdialysis" at the annual meeting of the College on Problems of Drug Dependence, San Juan, PR, June 22-27, 1996.

Dr. Bruce Vaupel, DIR, presented a paper entitled, "Rate of Morphine Administration Affects Subjective Responses of Experienced Heroin Users" at the International Narcotics Research Conference, Long Beach, CA, July 21-26, 1996.

Dr. Ronald Herning, DIR, presented a paper entitled, "Electrophysiological Findings in Substance Abuse" at the 3rd annual Psychiatric Electrophysiological Association in Miami, FL, May 1996.

Dr. Tsung Ping Su, DIR, presented a paper entitled, "Delta Opioid Peptide, DADLE, Attenuates METH-Induced DA Neurotoxicity in Mice" at the 1996 International Narcotics Research Conference, Long Beach, CA, July 21-26, 1996.

Dr. Jean Lud Cadet, DIR, presented a paper entitled, "Methamphetamine Induces Apoptosis in Neural Cells" at the annual meeting of the College on Problems of Drug Dependence, San Juan, PR, June 22-27, 1996.

Dr. Karen Bolla, DIR, presented a paper entitled, "Differential Effects of Withdrawal on Neurocognitive Functioning in Cocaine and Cocaine and Alcohol Abusers" at the annual meeting of the College on Problems of Drug Dependence, San Juan, PR, June 22-27, 1996.

Dr. Ronald Herning presented a paper entitled, "Gender Differences in Cocaine Dependence: Preliminary Neuropsychiatric Findings" at the annual meeting of the College on Problems of Drug Dependence, San Juan, PR, June 22-27, 1996.

Dr. Hema Mann, DIR, presented a paper entitled, "Multidrug Resistant (mdrla) Knockout Mice are Differentially Affected by Methamphetamine (METH) in Methylenedioxy-Methamphetamine (MDMA)", at the annual meeting of the College on Problems of Drug Dependence, San Juan, PR, June 22-27, 1996.

David A. Gorelick, M.D., Ph.D., Chief, Treatment Branch, DIR, gave grand rounds at the Neurology Service, West Los Angeles VA Medical Center, on Aug. 16, 1996. His topic was "Neurologic Consequences of Cocaine Use."

Jonathan L. Katz, DIR, was invited to present a paper entitled "Dopamine Uptake Inhibitors, Agonist Efficacy and Cocaine Abuse Treatments" as part of a symposium: Agonist Efficacy, Drug Dependence, and Medications Development at the Annual meeting of the College on Problems of Drug Dependence.

Sari Izenwasser, DIR, was invited to give a series of lectures to graduate students in the Department of Pharmacology at George Washington University School of Medicine.

Sari Izenwasser was selected to present a paper entitled "Regulation of Dopamine D2 Receptor Function by k-opioid Agonists: Biochemical and Neurochemical Studies" as part of a symposium: Opioid-Dopamine Interactions at the International Narcotics Research Conference.


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