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NIDA Home > Publications > Director's Reports > May, 2007 Index    

Director's Report to the National Advisory Council on Drug Abuse - May, 2007



Program Activities

New NIDA PAs

On February 16, 2007, NIDA issued the PA entitled NIDA Research Education Grants in Drug Abuse and Addiction (R25) (PAR-07-221). This FOA invites applications focused on research education and research curriculum development and/or program building in the area of drug abuse and addiction research. The focus should be primarily on clinical research, with preclinical research included to directly inform or provide a mechanistic foundation and/or for the purposes of supporting translational research training.

On February 21, 2007, NIDA issued the PA entitled Neuroscience Research on Drug Abuse (R01) (PA-07-226). Through this PA, the National Institute on Drug Abuse (NIDA) requests research grant applications in the areas of neuroscience and behavioral neuroscience research that are relevant to the understanding of the process(es) and mechanisms underlying drug abuse and addiction, including use, dependence, addiction, withdrawal, and treatment, and may be conducted using model systems, animals, and/or humans.

On February 21, 2007, NIDA issued the PA entitled Neuroscience Research on Drug Abuse (R21) (PA-07-227). Through this PA, the National Institute on Drug Abuse (NIDA) requests research grant applications in the areas of neuroscience and behavioral neuroscience research that are relevant to the understanding of the process(es) and mechanisms underlying drug abuse and addiction, including use, dependence, addiction, withdrawal, and treatment, and may be conducted using model systems, animals, and/or humans.

On February 22, 2007, NIDA issued the PA entitled Neuroscience Research on Drug Abuse (R03) (PA-07-228). Through this PA, NIDA requests research grant applications in the areas of neuroscience and behavioral neuroscience research that are relevant to the understanding of the process(es) and mechanisms underlying drug abuse and addiction, including use, dependence, addiction, withdrawal, and treatment, and may be conducted using model systems, animals, and/or humans.

On February 23, 2007, NIDA issued a PA entitled Collaborative Clinical Trials in Drug Abuse (R01) (PAR-07-232). Through this PA NIDA seeks to increase the collaboration of investigators at different sites in order to address critical issues in the treatment of substance-related disorders that require sample sizes greater than a single site can reasonably attain. The expectation for the collaborative effort is that there will be implementation of common clinical trials across different sites in order to study patient outcomes, patient factors, provider factors, setting characteristics, interactions of these, or other effects where pooled samples are appropriate and necessary for the hypotheses under consideration.

On March 22, 2007, NIDA issued a PA entitled Medications Development for the Treatment of Amphetamine and Amphetamine-Like Related Disorders (R01) (PA-07-333). The goal of this program announcement is to encourage preclinical and clinical research directed towards the identification, evaluation and development of safe and effective medications for the treatment of Amphetamine and Amphetamine-like Related Disorders (ARDs), most importantly methamphetamine abuse and methamphetamine dependence. According to the DSM-IV-TR, the class of amphetamine and amphetamine-like substances includes all substances with a substituted-phenylethylamine structure, such as amphetamine, dextroamphetamine, methamphetamine, and MDMA (3,4-methylenedioxymethamphetamine). Also included are those substances that are structurally different but have amphetamine-like action, such as methylphenidate, some agents used as appetite suppressants, and khat. Amphetamines, amphetamine-like substances and methamphetamine especially, are highly addictive central nervous system stimulants that can be injected, snorted, smoked, or ingested orally. Of all the ARDs, prevalence data is most readily available for methamphetamine abuse and dependence. This data indicates that methamphetamine use continues to be a major public health concern in the United States for all segments of the population. Methamphetamine is unique in that it can be easily manufactured in clandestine laboratories using store-bought materials and is the most prevalent synthetic drug manufactured in the United States. The ease of manufacturing methamphetamine and its highly addictive potential has caused the use of the drug to greatly increase throughout the Nation. The methamphetamine problem was originally concentrated in the West of the United States, but has since spread throughout almost every major metropolitan area in the country, due to the low cost, high availability, and addictive properties of this substance. There are currently no effective pharmacological treatments for ARDs and there has been limited research focused on the identification and development of medications to treat these disorders, as well as research on the health effects of chronic abuse. For these reasons, the NIDA is encouraging research in this area.

On March 22, 2007, NIDA issued a PA entitled Medications Development for the Treatment of Amphetamine and Amphetamine-Like Related Disorders (R21) (PA-07-334). The goal of this program announcement is to encourage preclinical and clinical research directed towards the identification, evaluation and development of safe and effective medications for the treatment of Amphetamine and Amphetamine-like Related Disorders (ARDs), most importantly methamphetamine abuse and methamphetamine dependence. According to the DSM-IV-TR, the class of amphetamine and amphetamine-like substances includes all substances with a substituted-phenylethylamine structure, such as amphetamine, dextroamphetamine, methamphetamine, and MDMA (3,4-methylenedioxymethamphetamine). Also included are those substances that are structurally different but have amphetamine-like action, such as methylphenidate, some agents used as appetite suppressants, and khat. Amphetamines, amphetamine-like substances and methamphetamine especially, are highly addictive central nervous system stimulants that can be injected, snorted, smoked, or ingested orally. Of all the ARDs, prevalence data is most readily available for methamphetamine abuse and dependence. This data indicates that methamphetamine use continues to be a major public health concern in the United States for all segments of the population. Methamphetamine is unique in that it can be easily manufactured in clandestine laboratories using store-bought materials and is the most prevalent synthetic drug manufactured in the United States. The ease of manufacturing methamphetamine and its highly addictive potential has caused the use of the drug to greatly increase throughout the Nation. The methamphetamine problem was originally concentrated in the West of the United States, but has since spread throughout almost every major metropolitan area in the country, due to the low cost, high availability, and addictive properties of this substance. There are currently no effective pharmacological treatments for ARDs and there has been limited research focused on the identification and development of medications to treat these disorders, as well as research on the health effects of chronic abuse. For these reasons, the NIDA is encouraging research in this area.

On March 30, NIDA issued a PA entitled NIDA Mentored Clinical Scientists Development Program Award in Drug Abuse and Addiction (K12) (PAR-07-346). The goal of NIH-supported career development programs is to help ensure that a diverse pool of highly trained scientists is available in adequate numbers and in appropriate research areas to address the Nation's biomedical, behavioral, and clinical research needs. The purpose of the NIDA Mentored Clinical Scientists Development Award in Drug Abuse and Addiction (K12) is to support the career development of clinical investigators who have made a commitment to research independence.

On April 3, 2007, NIDA issued a PA entitled AIDS-Science Track Award for Research Transition (R03) (PA-07-349). HIV/AIDS research is a major focus at NIDA, and this funding opportunity announcement (FOA) is designed to facilitate the entry of new investigators and early career investigators to the area of drug abuse research on HIV/AIDS. This FOA, AIDS--Science Track Award for Research Transition (A-START), solicits Small Research Grant (R03) applications to support feasibility, secondary data analysis, and small, self-contained studies on drug abuse and HIV/AIDS. This funding opportunity announcement (FOA) seeks to facilitate the entry of both newly independent and early career investigators to the area of drug abuse research on HIV/AIDS.

On April 24, 2007, NIDA issued a PA entitled Medications Development for the Treatment of Cannabis-Related Disorders (R01) (PA-07-365). This Funding Opportunity Announcement (FOA) solicits new or competing renewal Research Project Grant (R01) applications from institutions/ organizations that propose to conduct preclinical and clinical research directed towards the identification, evaluation and development of safe and effective medications for the treatment of Cannabis Related Disorders (CRDs) and their medical and psychiatric consequences. They include the Cannabis Use Disorders (CUDs) such cannabis abuse and dependence, the Cannabis Induced Disorders (CIDs) such as intoxication, psychosis, and anxiety, as well as the comorbidity of these disorders with other medical and psychiatric disorders (e.g., depression). Cannabis use includes marijuana, hashish, and other tetrahydrocannabinol (THC) containing substances. NIDA is encouraging research in this area because there is a high prevalence of marijuana use in the general population accompanied with an increasing misperception that its use poses low health risk, there is limited research in this area, and there are no effective pharmacological treatments available for these disorders.

On April 25, 2007, NIDA issued a PA entitled Medications Development for the Treatment of Cannabis-Related Disorders (R21) (PA-07-366). This funding opportunity announcement (FOA) solicits Exploratory/Developmental (R21) grant applications from applicant organizations that propose to conduct preclinical and clinical research directed towards the identification, evaluation and development of safe and effective medications for the treatment of Cannabis Related Disorders (CRDs) and their medical and psychiatric consequences. They include the Cannabis Use Disorders (CUDs) such cannabis abuse and dependence, the Cannabis Induced Disorders (CIDs) such as intoxication, psychosis, and anxiety, as well as the comorbidity of these disorders with other medical and psychiatric disorders (e.g., depression). Cannabis use includes marijuana, hashish, and other tetrahydrocannabinol (THC) containing substances. NIDA is encouraging research in this area because there is a high prevalence of marijuana use in the general population accompanied with an increasing misperception that its use poses low health risk, there is limited research in this area, and there are no effective pharmacological treatments available for these disorders.

International Program Announcement Expanded to R03 and R21 Grants

NIDA has expanded its Program Announcement (PA) on International Research Collaboration on Drug Addiction to use two additional funding mechanisms. In addition to the traditional Research Project Grants, known as R01 awards, scientists are now invited to submit grant applications that propose international collaborative research using the Small Grant Award, also known as an R03, and the Exploratory/Developmental Research Grants, or R21 awards. NIDA issues PAs to formally express ongoing interest in funding a particular area of science. Applications under the three PAs on International Research Collaboration may be for new or continuing funding and must:

Take advantage of special opportunities that exist outside the United States - such as unusual talent, resources, populations, or environmental conditions.

Be conducted by U.S. investigators in collaboration with non-U.S.-based investigators.

Address NIDA's scientific priority areas, which currently include linkages between HIV/AIDS and drug abuse, adolescent and prenatal tobacco exposure, methamphetamine abuse, inhalant abuse, and drugged driving.

Specific application requirements and deadlines differ for the three grant mechanisms and are available in the NIH Guide for Grants and Contracts:

R01: PA-07-275 (http://grants.nih.gov/grants/guide/pa-files/PA-07-275.html).

R03: PA-07-311 (http://grants.nih.gov/grants/guide/pa-files/PA-07-311.html).

R21: PA-07-310 (http://grants.nih.gov/grants/guide/pa-files/PA-07-310.html).

PAs and RFAs with Other NIH Components/Agencies

On March 23, 2007, NIDA, in collaboration with numerous other NIH components, issued a PA entitled International Research Collaboration - Basic Biomedical (FIRCA-BB) (R03)(PA-07-335). This funding opportunity facilitates collaborative basic biomedical research between scientists supported by the National Institutes of Health (NIH) and investigators in developing countries. For behavioral and social sciences research, see the companion Funding Opportunity Announcement (FOA), Fogarty "International Research Collaboration - Behavioral, Social Sciences" Research Award program (FIRCA-BSS) (PAR-06-437).

On March 27, 2007, NIDA, in collaboration with NIMH and NINR, issued a PA entitled HIV Treatment Adherence Research (R01) PA-07-338. This funding opportunity announcement (FOA) invites grant applications from applicant organizations to advance scientific research and intervention regarding HIV treatment adherence.

On March 27, 2007, NIDA, in collaboration with NIMH and NINR, issued a PA entitled HIV Treatment Adherence Research (R03) PA-07-339. This funding opportunity announcement (FOA) invites grant applications from applicant organizations to advance scientific research and intervention regarding HIV treatment adherence.

On March 27, 2007, NIDA, in collaboration with NIMH and NINR, issued a PA entitled HIV Treatment Adherence Research (R21) PA-07-340. This funding opportunity announcement (FOA) invites grant applications from applicant organizations to advance scientific research and intervention regarding HIV treatment adherence.

On March 29, 2007, NIDA in conjunction with numerous other NIH components, issued a PA entitled Innovations in Biomedical Computational Science and Technology (R01) (PA-07-344). The NIH is interested in promoting research and developments in computational science and technology that will support rapid progress in areas of scientific opportunity in biomedical research. As defined here, biomedical computing or biomedical information science and technology includes database design, graphical interfaces, querying approaches, data retrieval, data visualization and manipulation, data integration through the development of integrated analytical tools, and tools for electronic collaboration, as well as computational and mathematical research including the development of structural, functional, integrative, and analytical models and simulations.

On March 29, 2007, NIDA, in collaboration with NIEHS, issued a PA entitled Mechanism for Time-Sensitive Research Opportunities (R21) (PA-07-345). This Funding Opportunity Announcement (FOA) is intended to support substance abuse services research or hazard exposure - related research in rapidly evolving areas (e.g., changes in service systems, health care financing, policy, etc) where opportunities for empirical study are, by their very natures, only available through expedited award of support.

On April 2, 2007, NIDA, in collaboration with numerous other NIH components, issued a PA entitled AIDS International Training and Research Program (D43) (PAR-07-348). The purpose of this Funding Opportunity Announcement (FOA) is to invite applications from eligible institutions for innovative, collaborative research training programs that would contribute to the long-term goal of building sustainable research capacity in HIV-related conditions at institutions in low- and middle-income countries.

On February 21, 2007, NIDA, in collaboration with NIMH and NICHD, issued a PA entitled Developmental Psychopharmacology (R21) (PA-07-222). The purpose of this Funding Opportunity Announcement (FOA) is to request research applications to examine the neurobiological impact of psychotherapeutic medications upon the immature brain, with particular emphasis upon mapping the precise developmental profile of physiological response to psychotropic agents used in the treatment of mental disorders in children. Appropriate research includes studies in model systems, including animals, and in human populations.

On February 23, 2007, NIDA, in collaboration with numerous other NIH components issued a PA entitled Continued Development and Maintenance of Software (R01) (PAR-07-235). Biomedical research laboratories increasingly undertake a software development project to solve a problem of interest to that laboratory. These software packages sometimes become useful to a much broader community of users that can include translational and clinical researchers. The goal of this program announcement is to support the continued development, maintenance, testing and evaluation of existing software. The proposed work should apply best practices and proven methods for software design, construction, and implementation to extend the applicability of existing biomedical informatics/computational biology software to a broader biomedical research community.

On March 15, 2007, NIDA, in collaboration with NIAAA, issued a PA entitled Women and Sex/Gender Differences in Drug and Alcohol Abuse/Dependence (R01) (PA-07-329). The purpose of this Funding Opportunity Announcement (FOA) is to promote research on women and sex/gender differences in drug/alcohol abuse and dependence.

On March 15, 2007, NIDA, in collaboration with NIAAA, issued a PA entitled Women and Sex/Gender Differences in Drug and Alcohol Abuse/Dependence (R03) (PA-07-330). The purpose of this Funding Opportunity Announcement (FOA) is to promote research on women and sex/gender differences in drug/alcohol abuse and dependence.

On March 15, 2007, NIDA, in collaboration with NIAAA, issued a PA entitled Women and Sex/Gender Differences in Drug and Alcohol Abuse/Dependence (R21) (PA-07-331). The purpose of this Funding Opportunity Announcement (FOA) is to promote research on women and sex/gender differences in drug/alcohol abuse and dependence.

On Feburary 3, 2007, NIDA issued a Request for Information (RFI) entitled Community Input for Nominating Single Nucleotide Polymorphisms or Genes Associated with Drug Abuse and Related Psychiatric Co-morbidities to Develop a Custom SNP Neuroarray (NOT-DA-07-010). The purpose of this RFI is to solicit community input to develop and generate a single nucleotide polymorphism (SNP) array platform for studies investigating the genetics and pharmacogenetics of drug abuse and addiction and related psychiatric disorders. The Neuroarray would be made available competitively through standard NIH mechanisms to advance the understanding of genetic vulnerability to these specific public health disorders, and the genetic profiles of patients for targeted/tailored pharmacotherapies.

Response to PAs/RFAs

There has been a substantial response to the NIH Roadmap RFA entitled Facilitating Interdisciplinary Research via Methodological and Technological Innovation in the Behavioral and Social Sciences. http://grants.nih.gov/grants/guide/rfa-files/RFA-RM-07-004.html. NIDA is partnering with OBSSR on this Roadmap initiative, and is the lead Institute. Dr. Lisa Onken of DCNBR has been leading the effort on this RFA. The applications will be reviewed in June 2007.

Other Program Activities

Clinical Trials Network (CTN) Update

The CCTN received proposals in response to a NIH SBIR Contract Solicitation for Topic 089, Development of Practical Training Materials for Evidence-Based Treatment. A review meeting was held on March 13, 2007. Two awards are planned for this solicitation.

A total of 27 protocols have been initiated since 2001. A total of 7,732 participants enrolled in studies as of February 28, 2007. Of these studies, 19 have completed enrollment and locked the data; two completed enrollment and are in the follow-up phase; and four are currently enrolling. Two new protocols are in the development phase.

Primary outcome papers are published and dissemination materials have been developed with CSAT's ATTC on the following:

Protocol CTN 0001, Buprenorphine/Naloxone versus Clonidine for Inpatient Opiate Detoxification

Protocol CTN 0002, Buprenorphine/Naloxone versus Clonidine for Outpatient Opiate Detoxification

Protocol CTN 0005, MI (Motivational Interviewing) To Improve Treatment Engagement and Outcome in Subjects Seeking Treatment for Substance Abuse

Protocol CTN 0006, Motivational Incentives for Enhanced Drug Abuse Recovery: Drug Free Clinics

Protocol CTN 0007, Motivational Incentives for Enhanced Drug Abuse Recovery: Methadone Clinics

The following protocols have locked the data:

Protocol CTN 0003, Bup/Nx: Comparison of Two Taper Schedules

Protocol CTN 0004, MET (Motivational Enhancement Treatment) To Improve Treatment Engagement and Outcome in Subjects Seeking Treatment for Substance Abuse

Protocol CTN 0008, A Baseline for Investigating Diffusion of Innovation

Protocol CTN 0009, Smoking Cessation Treatment with Transdermal Nicotine Replacement Therapy in Substance Abuse Rehabilitation Programs

Protocol CTN 0010, (Buprenorphine/Naloxone Facilitated Rehabilitation for Opioid Dependent Adolescents/Young Adults)

Protocol CTN 0011, A Feasibility Study of a Telephone Enhancement Procedure (TELE) to Improve Participation in Continuing Care Activities

Protocol CTN 0012, Characteristics of Screening, Evaluation, and Treatment of HIV/AIDS, Hepatitis C Viral Infection, and Sexually Transmitted Infections in Substance Abuse Treatment Programs

Protocol CTN 0013, (Motivational Enhancement Therapy to Improve Treatment Utilization and Outcome In Pregnant Substance Abusers)

Protocol CTN 0016, Patient Feedback: A Performance Improvement Study in Outpatient Addiction Treatment

Protocol CTN 0017, (HIV and HCV Intervention in Drug Treatment Settings)

Protocol CTN 0018, (Reducing HIV/STD Risk Behaviors: A Research Study for Men in Drug Abuse Treatment)

Protocol CTN 0019, (Reducing HIV/STD Risk Behaviors: A Research Study for Women in Drug Abuse Treatment)

Protocol CTN 0020, (Job Seekers Training for Substance Abusers). This study was also conducted in a Navajo American Indian site, the Na'nizhoozhi Center, Inc. in Gallup, New Mexico, the first CTN study to be conducted there.

Protocol CTN 0021, (Motivational Enhancement Treatment to Improve Treatment Engagement and Outcome for Spanish-Speaking Individuals Seeking Treatment for Substance Abuse). This is the first Spanish-only protocol in the CTN.

These protocols have ended new enrollment and are in either follow-up or data-lock phase:

Protocol CTN 0014, Brief Strategic Family Therapy for Adolescent Drug Abusers (BSFT), has been implemented at eight sites. The study reached its enrollment target of 480 randomized participants in January 2007.

Protocol CTN 0015, (Women's Treatment for Trauma and Substance Use Disorder: A Randomized Clinical Trial) began in March 2004. The study reached its enrollment target in October 2005, and follow-up continues until spring 2007.

Four protocols are currently enrolling:

Protocol CTN 0027, Starting Treatment with Agonist Replacement Therapies (START) is a randomized, open-label, multi-center study that was developed in collaboration with the Division of Pharmacotherapies & Medical Consequences of Drug Abuse (DPMCDA). Enrollment began in April 2006. As of February 28, 2007, there were 216 randomized participants.

Protocol CTN 0028, Randomized Controlled Trial of Osmotic-Release Methylphenidate (OROS MPH) for Attention Deficit Hyperactivity Disorder (ADHD) in Adolescents with Substance Use Disorders (SUD). Enrollment is now open at 11 sites. Sixty-five participants have been randomized.

Protocol CTN 0029, A Pilot Study of Osmotic-Release Methylphenidate (OROS MPH) in Initiating and Maintaining Abstinence in Smokers with Attention Deficit Hyperactivity Disorder (ADHD). This study is being carried out at six community treatment sites across five Nodes. There are a total of 165 randomized participants.

Protocol CTN 0030, Prescription Opioid Addiction Treatment Study (POATS) is a randomized 2-phase, open-label, multi-center study in outpatient treatment settings. Pre-screening began in May 2006. The study is being carried out in 11 sites. Sixty-eight participants have been randomized.

Two protocols are in the development phase:

Protocol CTN 0031, Stimulant Abuser Groups to Engage in 12-Step (STAGE-12): Evaluation of a Combined Individual-Group Intervention to Reduce Stimulant and Other Drug Use by Increasing 12-Step Involvement. The DSMB approved the protocol on January 29, 2007. The process for selecting Community Treatment Programs (CTPs) to serve as research sites has proceeded in two waves for implementation. Three CTPs were selected for Wave 1, based on combined ranking of interviews and Executive Committee consensus. The three CTPs selected for Wave 1 are Maryhaven from the Ohio Valley Node, ChangePoint from the Oregon/Hawaii Node, and Recovery Centers of King County from the Washington Node. Currently, the protocol Executive Committee is working to finalize the Standard Operations Manual and the Therapy Training Manual.

Protocol CTN 0032, HIV Rapid Testing and Counseling Protocol. This protocol is under development. This study seeks to evaluate the most effective strategy to ensure that persons in drug treatment programs are tested for HIV and receive their HIV test results. The Centers for Disease Control and Prevention (CDC) has made it a priority to bring HIV rapid testing and counseling into outpatient health care settings for high-risk populations. Protocol 0032 was approved for development in late November 2006, and the protocol team meets regularly by conference call. The DSMB is being formed for possible submission of the completed protocol during summer/fall 2007.

In addition to the primary CTN trials, there are currently 28 funded studies supported by independent grants that use CTN studies as a platform.

NIDA's New and Competing Continuation Grants Awarded Since February 2007

Abrams, Donald I. -- University of California San Francisco
Opioid and Cannabinoid Pharmacokinetic Interactions

Abrantes, Ana M. -- Butler Hospital, Providence, RI
Behavioral Exercise Intervention For Smoking Cessation

Aharonovich, Efrat -- Columbia University Health Sciences
Cognition In Cocaine Dependence: Assessment & Therapy

Ahijevych, Karen L. -- Ohio State University
Menthol, Ethnicity and Nicotine Dependence

Akbarian, Schahram -- University of Massachusetts Medical School Worcester
Dopaminergic Signaling Modifies Stratial Histones

Aldrich, Jane V. -- University of Kansas Lawrence
Affinity Labels For Opioid Receptors

Aldrich, Jane V. -- University of Kansas Lawrence
Peptidic Ligands For Kappa Opioid Receptors

Aldridge, J. Wayne -- University of Michigan at Ann Arbor
Neural Coding of Reward In Ventral Forebrain

Alger, Bradley E. -- University of Maryland Baltimore Professional School
Endocannabinoids and GABAergic Control Of Plasticity

Allen, Sharon S. -- University of Minnesota Twin Cities
Menstrual Phase and Depression Symptoms In Acute Smoking Abstinence

Amen, Shelley L. -- Medical College of Wisconsin
Glutamate-Mediated Attenuation Of Cocaine Craving

Angulo, Jesus A. -- Hunter College
Methamphetamine and the Striatal Nk-1 Receptors

Aragona, Brandon J. -- University of North Carolina Chapel Hill
Dopamine, Accumbens Signaling & Associative Learning

Aston-Jones, Gary S. -- Medical University of South Carolina
Alterations In Reward Processing During Drug Abstinence

Balda, Mara A. -- University of Miami-Medical School
The Roles Of NNOS, Ontogeny, and Gender In Cocaine Sensitization

Balster, Robert L. -- Virginia Commonwealth University
The Behavioral Pharmacology Of Phencyclidine

Bank, Lewis I. -- Oregon Social Learning Center, Inc.
Motivational Parent Training In Community Corrections

Bannon, Michael J. -- Wayne State University
Cocaine-Binding Dopamine Transporter: Molecular Biology

Barker, Eric L. -- Purdue University West Lafayette
Psychostimulant Recognition By Serotonin Transporters

Barres, Ben A. -- Stanford University
Role Of Glia In the Formation Of Functional Synapses

Bartlett, Selena E.. -- Multispan, Inc.
Targeting Opioid Receptor Heterodimers For Pain Treatment

Baumann, Stephen B. -- Psychology Software Tools, Inc.
Virtual Reality and Functional MRI To Study Drug Craving

Bauzo, Rayna M. -- Emory University
Role Of Glutamate In Cocaine Behavioral Pharmacology

Bayer, Barbara M. -- Georgetown University
Lymphocyte Activity During Stress: Effects Of Morphine

Bechara, Antoine -- University of Iowa
Residual Effects Of Ecstasy On Decision-Making & Driving

Beckham, Jean C. -- Duke University
Optimal Smoking Cessation Treatment In PTSD

Beckham, Jean C. -- Duke University
The Effect Of Smoking On Startle & PPI In PTSD

Beckstead, Michael J. -- Oregon Health & Science University
Methamphetamine Effects On Dendrodendritic Dopamine Transmission In the VTA

Beeler, Jeff A. -- University of Chicago
Genetic Manipulation Of Phasic Dopaminergic Activity

Belousov, Andrei B. -- Tulane University of Louisiana
Cholinergic Regulation In the Hypothalamus

Benavides, David R. -- University of Texas Southwest Medical Center, Dallas
Minority Predoctoral Fellowship Program

Bergman, Jack -- Mc Lean Hospital, Belmont, MA
Behavioral Effects and Abuse Of Dopaminergic Drugs

Berridge, Craig W.-- University of Wisconsin Madison
Neurochemistry Of Amphetamine Induced Arousal

Bickel, Warren K. -- University of Arkansas Medical Sciences Little Rock
Improving Combined Buprenorphine-Behavioral Treatment

Bidlack, Jean M. -- University of Rochester
Opioid Receptors On Lymphocytes and Brain

Biederer, Thomas -- Yale University
Mechanisms Of Syncam-Induced Synapse Formation

Bierut, Laura J. -- Washington University
Case Control Candidate Gene Study Of Addiction

Bisaga, Adam M. -- New York State Psychiatric Institute
Memantine Naltrexone Treatment For Opioid Dependence

Blackler, Adele R. -- University of Colorado Denver/Health Sciences Center Aurora
Proteomic Characterization Of The Dopamine Transporter

Blakely, Randy D. -- Vanderbilt University
Regulation Of Serotonin Transporters

Blanco, Carlos -- New York State Psychiatric Institute
Smart: Improving Detection & Outcome Of Psychiatric Comorbidity In Drug Treatment

Blendy, Julie A. -- University of Pennsylvania
Molecular Genetic Analysis Of Drug Addiction

Blough, Bruce E. -- Research Triangle Institute
Potential Treatment Medications For Drug Abuse

Boeri, Miriam W. -- Kennesaw State University
Methamphetamine Use In the Suburbs: An Exploratory Study

Bonci, Antonello -- Ernest Gallo Clinic and Research Center
CRF Modulation Of NMDA Currents & Behavior In the VTA

Bonci, Antonello -- Ernest Gallo Clinic and Research Center
Synaptic Plasticity In the VTA After Behavioral Sensitization & Cocaine Self-Administration

Borenstein, Michael -- Biostatistical Programming Associates, Inc.
Forest Plots For Meta Analysis

Borenstein, Michael -- Biostatistical Programming Associates, Inc.
Power Analysis For Meta Analysis

Bosco, Giovanni -- University of Arizona
Fos, Jun & Synaptic Plasticity

Bost, Kenneth L. -- University of North Carolina Charlotte
Alters Immunity To Infections Of the Peripheral and Central Nervous Systems

Boudreau, Amy C. -- Rosalind Franklin University of Medicine & Science
Cocaine-Induced Plasticity In the Nucleus Accumbens

Boudreaux, Edwin D. -- Polaris Health Directions, Inc.
The Computer Assisted Brief Intervention For Tobacco (CABIT)

Bouhamdan, Mohamad -- Wayne State University
Rgs9-2 Protein: Novel Partners and Functional Roles

Bourgois, Philippe -- University of California San Francisco
The Logics For HIV Risk Among Homeless Heroin Injectors

Boutros, Nashaat N. -- Wayne State University
Cortical Excitability In Cocaine-Dependent Subjects

Bradberry, Charles W. -- University of Pittsburgh at Pittsburgh
CNS Consequences Of Chronic Cocaine Self-Administration

Brady, Kathleen T. -- Medical University of South Carolina
South Carolina Consortium Of the Clinical Trials Network

Brady, Kathleen T. -- Medical University of South Carolina
Drug Abuse Research Training (DART) Program

Brady, Kathleen T. -- Medical University of South Carolina
South Carolina Consortium Of the Clinical Trials Network

Bridges, Robert S. -- Tufts University Boston
Parenting and the Brain

Bromberg, Jonas I. -- Inflexxion, Inc.
Web-Based Support To Self-Manage Migraine Pain

Brook, Judith S. -- New York University School of Medicine
Drug Use and Problem Behaviors In Minority Youth

Brook, Judith S. -- New York University School of Medicine
Etiology and Consequences Of Adolescent Drug Use (K05)

Brooner, Robert K. -- Johns Hopkins University
Services Research: Psychiatric Comorbidity In Drug Abuse

Brown, Alison H. -- University of California Los Angeles
Women, Methamphetamine and Sex

Brown, Lawrence S. -- Addiction Research and Treatment Corp
Electronic Information System To Enhance Practice At An Opioid Treatment Program

Bruno, John P. -- Ohio State University
High-Speed Detection Of Stimulant-Induced Cortical ACH Release

Buch, Shilpa J. -- University of Kansas Medical Center
HIV-Encephalitis and Cocaine Abuse: Mechanism Of Synergy and Therapy

Bucholz, Kathleen K. -- Washington University
Gene Environment In Outcomes Of Offspring Of Twins With Substance Use Disorders

Bunt, Gregory -- Daytop Village
International Society Of Addiction Medicine Conference

Burdzovic Andreas, Jasmina -- Brown University
Substance Use In Adolescents From High-Risk Neighborhoods: Risk and Protection

Burke, Kathryn A. -- University of Maryland Baltimore Professional School
Associative Basis Of Conditioned Reinforcement

Butelman, Eduardo R. -- Rockefeller University
Kappa-Agonist Effects Of the Hallucinogen Salvinorin A

Cabral, Guy A. -- Society on Neuroimmune Pharmacology
13th-17th Conferences: Drug Abuse, Immune Modulation and AIDS

Cabral, Guy A. -- Virginia Commonwealth University
Cannabinoid Modulation Of Macrophage Function

Caggiula, Anthony R. -- University of Pittsburgh at Pittsburgh
Effects Of Self Administered Versus Noncontigent Nicotine

Campbell, William. B -- Medical College of Wisconsin
Biochemistry Of Anandamide, and Endogenous Cannabinoid

Capaldi, Deborah M. -- Oregon Social Learning Center, Inc.
Risk For Dysfunctional Relationships For Young Adults

Carlezon, William A. -- McLean Hospital, Belmont, MA.
Biobehavioral Mechanisms Of Drug Reward and Addiction

Carr, Kenneth D. -- New York University School of Medicine
CNS Mechanisms That Modulate Reward

Carroll, Kathleen M. -- Yale University
Maximizing CBT's Efficacy With Medication & CM

Carroll, Marilyn E. -- University of Minnesota Twin Cities
Primate Model Of Drug Abuse: Intervention Strategies

Carroll, Marilyn E. -- University of Minnesota Twin Cities
Animal Models For the Prevention and Treatment Of Drug Abuse

Caster, Joseph M. -- Duke University
Adolescent Vulnerbility To Neuroplastic Changes Induced By High Dose Cocaine

Chamberlain, Patricia -- Oregon Social Learning Center, Inc.
Preventing Behavior and Health Problems In Foster Teens

Chambers, Robert Andrew -- Indiana University-Purdue University at Indianapolis
Integrated Neurobiology Of Addiction and Mental Illness

Chang, Linda -- University of Hawaii at Manoa
Neuroimaging and Mentoring In Drug Abuse Research

Chang, Sulie L. -- Seton Hall University
Morphine Actions On the Immune System

Chang, Sulie L. -- Seton Hall University
Opiate's Effects On the Inflammation and Cytotoxicity In HIV-1 Transgenic Rat

Chavkin, Charles -- University of Washington
Regulation Of Opioid Signaling By Tyr-Phosphorylation

Chavkin, Charles -- University of Washington
Opioid Mediation Of Stress-Potentiated Cocaine Response

Cinciripini, Paul M. -- University of Texas MD Anderson Cancer Center
A Mood Management Intervention For Pregnant Smokers

Clark, Ann S. -- Dartmouth College
AAS and the Neurobiology Of Social Behaviors

Clatts, Michael C. -- National Development & Research Institutes
Ethno-Epidemiology In An Emergent MSM Risk Environment

Cochran, Susan D. -- University of California Los Angeles
Drug Use, HIV, and Other Comorbidities In A Vulnerable Population

Cohen, Mardge H. -- Hektoen Institute For Medical Research
Chicago Consortium Women's Interagency HIV Study Lll

Colbern, Deborah L. -- Beemnet, Inc.
National Kids Judge! Neuroscience Fairs Partnership

Colder, Craig R. -- State University of New York at Buffalo
Motivation In Context: Risk For Early Substance Use

Colfax, Grant N. -- San Francisco Department of Public Health
Club-Drugs and HIV Risk Behavior In High-Risk Men

Collins, Allan C. -- University of Colorado at Boulder
Studies With Nicotinic Null Mutant Mice

Comer, Sandra D. -- New York State Psychiatric Institute
Precription Opioid Effects In Drug and Non-Drug Abusers

Conger, Rand D. -- Iowa State University
Economic Stress & Child Development Across 3 Generations

Cooper, Donald C. -- University of Texas Southwest Medical Center/Dallas
DNA Microarray Analysis Of Neuronal Excitability

Corbin, Joshua G. -- Children's Research Institute
Development Of the Basal Telencephalic Limbic System

Cottler, Linda B. -- Washington University
Prescription Drug Misuse, Abuse and Dependence

Coviello, Donna M. -- University of Pennsylvania
Employment Intervention For Offenders

Cravatt, Benjamin F. -- Scripps Research Institute
FAAH: Structure, Function, and In Vivo Inhibition

Crowley, Thomas J. -- University of Colorado Denver/Health Science Center Aurora
Substance Dependent Adolescents: Imaging Risk-Taking

Dackis, Charles -- University of Pennsylvania
Modafinil Treatment For Cocaine Dependence

Dallery, Jesse -- University of Florida
Effects Of Nicotine On Environmental Stimuli

Dallery, Jesse -- University of Florida
A Home-Based Behavioral Treatment For Cigarette Smoking

Davies, Robert D. -- University of Colorado Denver/Health Science Center Aurora
Martial Arts As Early Intervention For Teen Drug Abuse

Davis, Thomas P. -- University of Arizona
Blood-To-CNS Drug Uptake In Pain/Rheumatoid Arthritis

Day, Nancy L. -- University of Pittsburgh at Pittsburgh
Prenatal Marijuana Exposure: Long-Term Outcomes

De Wit, Harriet -- University of Chicago
Drug Abuse and Impulsivity: Human Laboratory Models

Deadwyler, Samuel A. -- Wake Forest University Health Sciences
Hippocampus Correlates Of Drug Abuse In Rats

Decharms, Christopher -- Omneuron, Inc.
Measurement and Control Of Patterned Brain Activation Using Real Time FMRI

Deleo, Joyce A. -- Dartmouth College
Alternatives To Opioids For Chronic Pain: Part IV

Deren, Sherry -- National Development & Research Institutes
High Risk Drug Use & HIV-Learning From The NYC Epidemic

Desbiens, Sophie C. -- Boston University Medical Campus
CREB Mediated GABA-B Receptor Regulation In the Nucleus Accumbens

D'esposito, Mark -- University of California Berkeley
Dopaminergic Modulation Of Frontostriatal Function

Diamond, Adele D. -- University of British Columbia
Cognitive Functions Linked To Frontal Lobe

Diantonio, Aaron -- Washington University
Molecular Pathways Regulating Synaptic Growth

Dietz, David M. -- Florida State University
Individual Differences In Sensitization To Amphetamine

Dimeff, Linda A. -- Behavioral Tech Research, Inc.
Computer Based Training In DBT-S Behavioral Analysis

Dominguez, Hector D. -- San Diego State University
Behavioral Effects Of Neonatal Methamphetamine Exposure

Dorn, Lorah D. -- Children's Hospital Medical Center, Cincinnati
Smoking and Metabolic Complications In Adolescent Girls

D'souza, Deepak C. -- Yale University
Neurobiology Of Cannabis Effects

Dunlap, Eloise E. -- National Development & Research Institutes
Disruption and Reformulation Of Illicit Drug Markets Among New Orleans Evacuees

Dykstra, Linda A. -- University of North Carolina Chapel Hill
Opioid Analgesics: Pharmacological & Behavioral Factors

Eby, Lillian T. -- University of Georgia
Clinical Supervision and Turnover In Substance Abuse Treatment

Eisch, Amelia J. -- University of Texas Southwest Medical Center, Dallas
Regulation Of Adult Neurogenesis By Opiates

Ellinwood, Everett H. -- Duke University
Cocaine Withdrawal: A Window Of Treatment Opportunity

Elmer, Gregory I. -- University of Maryland Baltimore Professional School
Microarray Analysis Of Morphine's Behavioral Effects

Epperson, Cynthia N. -- Yale University
Sex, GABA and Nicotine: A 1h-MRS Study

Ettenberg, Aaron -- University of California Santa Barbara
Mechanisms Of Opiate and Stimulant Drug Reinforcement

Evans, Suzette M. -- New York State Psychiatric Institute
Vulnerability To Anxiolytic Abuse In Women

Fanous, Sanya -- Tufts University Boston
Social Defeat Stress and Cross-Sensitization: The Role Of Mesocorticolimbic BDNF

Fantegrossi, William E. -- Emory University
Effects Of Self-Administered On Brain and Behavior In Rhesus Monkeys

Feelisch, Martin -- Boston University Medical Campus
A Nitric Oxide(No)-Based Metabonomic Approach To Investigate Tobacco Addiction

Fendrich, Michael -- University of Wisconsin Milwaukee
Secondary Analysis Of Substance Use In Men

Ferguson, Susan M. -- University of Washington
Role Of 5HT6 Receptors In Drug Reward

Feske, Ulrike -- University of Pittsburgh at Pittsburgh
Drug Abuse and Risky Sex In Borderline Personality

Field, Julie R. -- Vanderbilt University
Structure-Guided Analysis Of the Serotonin Transporter

Filizola, Marta -- Weill Medical College of Cornell University
Opioid Receptor Oligomerization: Prediction & Validation

Filizola, Marta -- Weill Medical College of Cornell University
Informatics Of GPCR Dimers In Drug Abuse Mechanisms

Finn, Peter R. -- Indiana University Bloomington
Attention-Biases and Hot Cognition In Drug Dependence

Firpo, Meri T. -- University of Minnesota Twin Cities
Essential Human Embryonic Stem Cell Culture Methods

Fite, Paula J. -- State University of New York at Buffalo
Pathways From Subtypes Of Aggression To Substance Use

Fleckenstein, Annette -- University of Utah
Psychostimulants and Monoamine Transporters

Fleckenstein, Annette -- University of Utah
Drug Abuse and Regulatory Enzymes Of Biogenic Amines

Fleckenstein, Annette -- University of Utah
K02 Application

Foltin, Richard W. -- New York State Psychiatric Institute
Anorectic Drugs: Abuse and Behavioral Mechanisms Of Action

Fontanilla, Dominique A. -- University of Wisconsin Madison
Characterization Of the Sigma-1 Receptor

Forrester, Janet E. -- Tufts University Boston
Nutritional Status In HIV Hispanic Drug Abusers

Fowler, Melissa A. -- University of Texas Southwest Medical Center, Dallas
TRPC Channels In Dopamine Regulation Of Prefrontal Cortical Excitability

Fox, Nathan A. -- University of Maryland
Early Temperament and Social Behavior In Adolescence

France, Charles P. -- University of Texas Health Sciences Center San Antonio
Behavioral Pharmacology Of Drug Dependence

French, Michael T. -- University of Miami Coral Gables
Economic Evaluation Methods: Development and Application

Friedman, Jeffrey M. -- Rockefeller University
Mapping Neural Circuits Using Pseudorabie Virus Vectors

Fuchs Lokensgard, Rita A. -- University of North Carolina Chapel Hill
Neural Bases Of Drug Context-Induced Cocaine Seeking

Gabuzda, Dana H. -- Dana-Farber Cancer Institute
Monocyte Viral Reservoirs In HIV-1 Dementia

Galloway, Matthew P. -- Wayne State University
High Field MRS Assessment Of Stimulant Exposure In Rats

Garner, Craig C. -- Stanford University
Sap97 Isoforms In Trafficking Synaptic Glur1

Garvey, Arthur J. -- Harvard University Medical School
Front-Loaded Counseling To Treat Tobacco Addiction

Gebhart, Gerald F. -- University of Pittsburgh at Pittsburgh
Mediators and Modulation Of Nociception

Gelberg, Lillian -- University of California Los Angeles
Homeless Women: Drugs, Race/Ethicity, and Health Care

Gelernter, Joel E. -- Yale University
Approaches To the Genetics Of Substance Dependence

Gerak, Lisa R. -- University of Texas Health Science Center San Antonio
Behavioral Effects Of Neuroactive Steroids

Gewirtz, Jonathan C. -- University of Minnesota Twin Cities
Neural Substrates Of Anxiety In Acute Opiate Dependence

Gifford, Elizabeth J. -- Duke University
Multilevel Modeling Of Inpatient Care: Comorbid Youth

Gilbert, David G. -- Southern Illinois University Carbondale
NRT & Bupropion Mechanisms Of Efficacy In Smokers

Glass, Michael J. -- Weill Medical College of Cornell University
Opioids and Conditional Amygdala NMDA Receptor Knockout

Glennon, Richard A. -- Virginia Commonwealth University
Chemical/Behavioral Studies On Hallucinogenic Agents

Glenzer, Vicky Ann -- Oregon Center For Applied Science, Inc.
Internet Stepparent Training For Parents Of Adolescents

Goeders, Nicholas E. -- Louisiana State University Health Science Center Shreveport
Environmental Influences On Cocaine Self-Administration

Gordon, Judith S. -- Oregon Research Institute
Tobacco Cessation Via Doctors Of Chiropractic

Grace, Anthony A. -- University of Pittsburgh at Pittsburgh
Stress-Induced Alterations In Amygdala-LC Interactions

Greengard, Paul -- Rockefeller University
Drugs Of Abuse
-- Role Of Protein Phosphorylation

Greenwell, Thomas N. -- Scripps Research Institute
Role Of the Bed Nucleus In Opiate Dependence

Grella, Christine E. -- University of California Los Angeles
Gender Differences In A Follow-Up Of Opiate Users In California

Guydish, Joseph R. -- University of California San Francisco
Organizational Change and Nicotine Dependence Treatment

Gwaltney, Chad J. -- Brown University
Ecological Momentary Assessment Of Adolescent Smoking Cessation

Haber, Suzanne N. -- University of Rochester
Reward, Compulsions and Habit Formation

Hammond, Donna L. -- University of Iowa
Opioid Mechanisms Of Analgesia

Hampson, Robert E. -- Wake Forest University Health Sciences
Cannabinoid Effects On Sensory Processing In Brain

Hanlon, Colleen A. -- Wake Forest University Health Sciences
Neuroimaging Of Motor Control In Chronic Cocaine Users

Hanson, Glen R. -- University of Utah
Pharmacology and Toxicology Of Methamphetamine Abuse

Hanson, Glen R. -- University of Utah
Neurochemical Alterations By Designer Drugs

Harden, Kathryn P. -- University of Virginia Charlottesville
Religiosity and Adolescent Problem Behavior

Hargreaves, Kenneth M. -- University of Texas Health Science Center San Antonio
Peripheral Mechanisms Of Opioid Analgesia

Hargreaves, Kenneth M. -- University of Texas Health Science Center San Antonio
Cannabinoid Modulation Of Capsaicin-Sensitive Nociceptors

Harris, Kathleen Mullan -- University of North Carolina Chapel Hill
The National Longitudinal Study Of Adolescent Health

Harrod, Steven B. -- University of South Carolina at Columbia
Prenatal Iv Nicotine: Long-Term Vulnerability To Stimulant Drugs

Hawkins, J. David -- University of Washington
Substance Use and the Consolidation Of Adult Roles

Hayashi, Yasunori -- Massachusetts Institute of Technology
Optical Detection Of the Molecular Processes Underlying Hippocampal LTP

Heatherton, Todd F. -- Dartmouth College
Effects Of Social Context On the Neural Correlates Of Cue Reactivity

Heberlein, Ulrike A. -- University of California San Francisco
Molecular Genetics Of Psychostimulant Action

Hecht, Michael L. -- Pennsylvania State University-University Park
Drug Resistance Strategies Minority Project

Heinemann, Stephen F. -- Salk Institute For Biological Studies
Role Of Brain Nicotinic Receptors In Addiction Behaviors

Heinricher, Mary M. -- Oregon Health & Science University
Neural Circuitry Of Improgran Analgesia

Henggeler, Scott W. -- Medical University of South Carolina
Vocational Outcomes For Youth With Substance Abuse Problems and High HIV Risk

Henggeler, Scott W. -- Medical University of South Carolina
Testing Therapist Training Interventions To Implement An EBT For Adolescents

Henry, Kimberly L. -- Colorado State University-Fort Collins
Substance Use Consequences Of School Disengagement

Hersh, Louis B. -- University of Kentucky
Degradation Of Opioid Peptides

Hjelmstad, Gregory O. -- Ernest Gallo Clinic and Research Center
Plasticity Of Kappa Opioid Function In Reward Circuitry

Holtman, Joseph R. -- Yaupon Therapeutics, Inc.
Nornicotine For Treatment Of Pain

Holtman, Joseph R. -- Yaupon Therapeutics, Inc.
Norketamine For Treatment Of Pain

Hooven, Carole -- University of Washington
Understanding Parent Retention In Indicated Prevention

Howell, Leonard L. -- Emory University
Neuropharmacology Of Cocaine In Nonhuman Primates

Howell, Leonard L. -- Emory University PET Imaging and Cocaine Neuropharmacology In Mon
keys

Howells, Richard D. -- University of Medicine/Dentistry of New Jersey - New Jersey Medical School
Purification and Mass Spectrometry Of Opioid Receptors

Hruby, Victor J. -- University of Arizona
New Modalities For Treatment Of Pain and Drug Abuse

Huang, Bin -- Children's Hospital Medical Center, Cincinnati
Innovative Modeling Of Puberty and Substance Use Risk

Hurd, Yasmin L. -- Mount Sinai School of Medicine of NYU
Dynorphin /Kappa Mesolimbic System In Heroin Abuse

Hurt, Richard D. -- Mayo Clinic College of Medicine, Rochester
Efficacy Of Methylphenidate For Treating Tobacco Dependence

Iacono, William G. -- University of Minnesota Twin Cities
Twin Study Of ADHD, CD and Substance Abuse

Information Management Consultants -- Information Management Consultants
SBIR Phase 1: Topic #71/ Microarray Technology Applications In DA & Addiction

Inlander, Robin -- Behavioral Research, Inc.
SBIR Phase 2: New Risk Assessment/Intervention For Pregnant Woman

IQ Solutions -- IQ Solutions
NIDA Research Dissemination

Izenwasser, Sari -- University of Miami-Medical School
Neurochemical Consequences Of Drug In Adolescent Rats

Janda, Kim D. -- Scripps Research Institute
Immunopharmacotherapy For the Treatment Of Cocaine Abuse

Janoff, Edward N. -- University of Colorado Denver/Health Science Center Aurora
University Of Colorado Center For AIDS Research

Javitch, Jonathan A. -- New York State Psychiatric Institute
Dopamine Transporter: Substrate & Cocaine Binding Sites

Johnson, Bankole A. -- University of Virginia Charlottesville
Medication Development For Cocaine Dependence

Johnson, Jennifer E. -- Brown University
Group IPT For Women Prisoners With Comorbid Substance Use and Depression

Kadden, Ronald M. -- University of Connecticut School of Medicine/Dentistry
Contingency Management For Marijuana Dependence

Kahler, Christopher W. -- Brown University
Mechanisms Linking Hostility and Smoking

Kalivas, Peter W. -- Medical University of South Carolina
Glutamate and Craving For Cocaine

Kalivas, Peter W. -- Medical University of South Carolina
Neurobiology Of Addiction Research Center (NARC)

Kalivas, Peter W. -- Medical University of South Carolina
Stress-Induced Reinstatement Of Cocaine-Seeking Behavior

Kalman, David W. -- Boston University Medical Campus
Bupropion Treatment For Smokers In Recovery

Kaminski, Norbert E. -- Michigan State University
CB1/CB2-Dependent and -Independent T Cell Modulation

Kaplan, Howard B. -- Texas A&M University System
Drug Abuse and Other Deviant Adaptations: Two Generation

Kauer, Julie A. -- Brown University
Inhibitory Synaptic Transmission and Drugs Of Abuse

Kaufman, Marc J. -- McLean Hospital, Belmont, MA
Chronic Drug Exposures In Monkeys: Serial MRI Studies

Kelley, Ann E. -- University of Wisconsin Madison
Plasticity and Learning In A Corticostriatal Network

Kelley, Ann E. -- University of Wisconsin Madison
Corticostriatal-Hypothalamic Circuitry and Food Reward

Kenny, Paul J. -- Scripps Research Institute
Mechanisms Of Nicotine Reinforcement In Mice

Kharasch, Evan D. -- Washington University
Opioids In Cancer Pain & Drug Abuse: Optimizing Therapy

Kilts, Clinton D. -- Emory University
An fMRI Study Of the Impact Of Stress On Drug Addiction

King, Ian F. -- University of California San Francisco
Role Of Gsk-3 In Drosophila Behavioral Plasticity

King, Jean A. -- University of Massachusetts Medical School Worcester
Imaging Nicotine-Induced Behavioral Sensitization With fMRI

Kirisci, Levent -- University o Pittsburgh at Pittsburgh
Quantifying and Tracking Risk For Substance Use Disorder

Kirk, Gregory -- Johns Hopkins University
Natural History Of HIV Infection In Injection Drug Users

Kish, Stephen J. -- Centre For Addiction and Mental Health
Brain Serotonin Transporter In Ecstasy and MDA Users

Klein, Thomas W. -- University of South Florida
Role Of Cannabinoid 2 Receptors In B Lymphocyte Function

Knight, John R. -- Children's Hospital Boston
Medical Office Intervention For Adolescent Drug Use

Knudsen, Hannah K. -- University of Georgia
Smoking Cessation Practices In Community Treatment Programs

Knuepfer, Mark M. -- Saint Louis University
Effects Of Chronic Stress Or Psychostimulants On CNS and ANS

Ko, Jane L. -- Seton Hall University
Molecular Basis Of Mu-Opioid Receptor Gene Regulation

Kollins, Scott H. -- Duke University
Methylphenidate Abuse Potential In ADHD Adults

Koob, George F. -- Scripps Research Institute
Neuronal Substrates Of Cocaine Reward

Koob, George F. -- Scripps Research Institute
Dopamine Partial Agonists and Psychostimulant Dependence

Kornetsky, Conan -- Boston University Medical Campus
Brain Stimulation Models Of Drug Abuse

Kosofsky, Barry E. -- Weill Medical College of Cornell University
Addiction Following Prenatal Cocaine Exposure

Kosofsky, Barry E. -- Weill Medical College of Cornell University
Structural MR Analyses Of Drug Exposed Brains

Kosterman, Richard -- University of Washington
Social Development and Psychopathology Into Adulthood

Kravitz, Alexxai V. -- University of Pennsylvania
Accumbal Activity Under Drug and Non-Drug Rewarded Tasks

Kreek, Mary J. -- Rockefeller University
Addictive Drugs-Pharmacology & Physiology

Kressel, David -- National Development & Research Institutes
Therapeutic Communities: A Three Country Comparison

Krishnan, Balaji -- University of Texas Medical Branch Galveston
Lipase In Cocaine Cue Associations In the Amygdala

Kuhar, Michael J. -- Emory University
Mechanisms Of Drugs Of Abuse

Kuhn, Donald M. -- Wayne State University
Methamphetamine Neurotoxity and Microglial Activation

Kuhn, Donald M. -- Wayne State University
Neurotoxic Amphetamines Radicals & 5HT Neurons

Kulak, Jennifer M. -- Thomas Jefferson University
Improving An Animal Model Of Tobacco Addiction

Lalumiere, Ryan T. -- Medical University of South Carolina
NAc1 and Proteasome Involvement In Cocaine Use

Lamb, Richard J. -- University of Texas Health Sciences Center
Increasing Contingency Management Success Using Shaping

Larkby, Cynthia A. -- University of Pittsburgh at Pittsburgh
Child Abuse, Violence, and PTSD In Early Substance Use

Larson, Mary J. -- New England Research Institutes, Inc.
Enhanced Web Training For Community Based Counselors: Teach-CBT

Law, Wai Tak -- Portascience, Inc.
A Rapid and Sensitive Test For Gamma-Hydroxybutyrate

Lee, David J. -- State University of New York at Buffalo
The Role Of Glutamate In the Action Of LSD

Lee, Yue-Wei (David) -- McLean Hospital, Belmont, MA
Pharmacology and Metabolism Of Salvia Divinorum

Leibowitz, Sarah F. -- Rockefeller University
Hypothalamic Neurotransmitter Systems & Eating Behavior

Leigh, Barbara C. -- University of Washington
Daily Self-Reports Of Injection Drug Use and Risk

Leonard, Sherry S. -- University of Colorado Denver/Health Science Center Aurora
Regulation Of Alpha 7 Nicotinic Receptor Assembly In Human Smokers

Lester, Barry M. -- Lester, Barry M.
Maternal Opioid Treatment: Human Experimental Research

Lester, Henry A. -- California Institute of Technology
Biogenic Amine Transporters-Structure/Function

Lester, Robin A. -- University of Alabama at Birmingham
Subunit-Specific Regulation/Neuronal Nicotinic Receptors

Levin, Edward D. -- Duke University
Adolescence: A Sensitive Period For Nicotine Addiction

Li, Ming D. -- University of Virginia Charlottesville
Fine Mapping Susceptibility Loci For Nicotine Dependence

Li, Ming D. -- University of Virginia Charlottesville
Deciphering Genes and Pathways In Nicotine Dependence

Liao, Dezhi -- University of Minnesota Twin Cities
Opioid Receptors In Excitatory Synapses

Libretto, Salvatore -- Danya International, Inc.
Conflict Resolution

Lichstein, Kenneth L. -- University of Alabama in Tuscaloosa
Treating Addiction To Sleep Medication

Ling, Walter -- University of California Los Angeles
National Drug Abuse Treatment Clinical Trials Network

Lipton, Jack W. -- University of Cincinnati
Neurochemical Sequelae Of Prenatal

Liu, Hongjie -- Wayne State University
A Pilot Study Of School-Based HIV Intervention In China

Liu, Xiu -- University of Pittsburgh at Pittsburgh
Neuropharmacology Of Cue-Induced Nicotine Relapse

Loeber, Rolf -- University of Pittsburgh at Pittsburgh
Development Of Substance Use In Girls

Loh, Horace H. -- University of Minnesota Twin Cities
Center On Molecular and Cell Biology Of Drug Abuse

Lord, Sarah E -- Inflexxion, Inc.
Internet-Based Drug Prevention Education For College Students

Lostutter, Ty W. -- University of Washington
Web-Based Prevention For At-Risk Gamblers

Lowen, Steven B. -- McLean Hospital, Belmont, MA
Neurobiological Bases Of Drug Abuse: Novel Techniques

Luu, Percy -- Stanford University
PSD-95 In Drug-Induced Plasticity Of Accumbens Synapses

Mackie, Kenneth P. -- University of Washington
Neuronal Cannabinoid Receptor: Function and Regulation

Mahata, Sushil K. -- University of California San Diego
Chromaffin Cell Physiology: Novel Molecular Approaches

Makriyannis, Alexandros -- Northeastern University
Studies On Cannabinoid Effects and Cannabimimetic Drugs

Makriyannis, Alexandros -- Northeastern University
Cannabinergic Medications For Methamphetamine Addiction

Malanga, C. J. -- University of North Carolina Chapel Hill
Effect Of Prenatal Cocaine Exposure On Brain Reward

Malcolm, Robert J. -- Medical University of South Carolina
A Controlled Trial Of NAC For Cocaine Dependence

Malison, Robert T. -- Yale University
Drug Abuse, Sleep, and Cognition

Mao, Jianren -- Massachusetts General Hospital
Opioid-Induced Pain Sensitivity: Clinical Diagnosis and Management

Marcus, Bess H. -- Miriam Hospital
Using A YMCA Exercise Program To Enhance Nicotine Dependence Treatment For Women

Marenco, Luis N. -- Yale University
Mediated Integration Of Neuroscience Resources

Mariani, John J. -- Columbia University Health Sciences
Anticonvulsant Pharmacotherapy For Sedative-Hypnotic Use Disorders

Markou, Athina -- University of California San Diego
Neurobiology Of Nicotine Reward and Withdrawal

Markou, Athina -- University of California San Diego
Neurobiology Of Nicotine Reward and Dependence In Mice

Marmorstein, Naomi R. -- Rutgers The State University of New Jersey New Brunswick
Longtudinal Relations Between Internalizing Disorders and Substance Use Problems

Marsch, Lisa A. -- National Development & Research Institutes
Science-Based Treatment For Opioid-Dependent Adolescents

Marsch, Lisa A. -- Healthsim, Inc.
Expanding Computer-Based Drug Abuse Prevention

Marshall, John F. -- University of California Irvine
Erk Signaling, Neural Circuits and Reconsolidation Of Cocaine-Cue Memories

Martin, Catherine A. -- University of Kentucky
Modafinil and Smoking Cessation

Martin, Eileen M. - University of Illinois at Chicago
Cognitive Neuropsychology Of HIV and Drug Abuse

Martin, Peter R. -- Martin, Peter R.
Maternal Opioid Treatment: Human Experimental Research

Martinez, Charles R. -- Oregon Social Learning Center, Inc.
Linking Acculturation To Latino Adolescent Substance Use

Martone, Maryann E. -- University of California San Diego
Development Of A 3-D Cell-Centered Neuronal Database

Marusich, Julie A. -- University of Florida
Contingent Tolerance To Cocaine In Pigeons

Matta, Shannon G. -- University of Tennessee Health Science Center
Gestational Drugs and Nicotine Self-Administration

Mayes, Linda C. -- Yale University
Cocaine-Exposed Children & ERP Studies Of Neurocognition

Mccabe, Sean E. -- University of Michigan at Ann Arbor
Epidemiology Of Prescription Drug Abuse In the United States

Mccance-Katz, Elinore F. -- Virginia Commonwealth University
Role Of Buprenorphine In Improving Clinical Care In Opioid Addiction and HIV

Mccarty, Dennis -- Oregon Health & Science University
Oregon/Hawaii Node, Clinical Trials Network

Mccarty, Dennis -- Oregon Health & Science University
Adoption Of Buprenorphine In An HMO Setting

Mcclung, Colleen A. -- University of Texas Southwest Medical Center, Dallas
The Role Of Circadian Genes In Drug Addiction

Mccollister, Kathryn E. -- University of Miami-Medical School
Substance Abuse Treatment In Criminal Justice Settings

Mccurdy, Christopher R. -- University of Mississippi
Novel Pharmacologic Interventions For Drugs Of Abuse

Mcgehee, Daniel S -- University of Chicago
Nicotinic Modulation Of The Mesoaccumbens DA System

Mcgovern, Mark P. -- Dartmouth College
Cognitive Therapy For PTSD In Addiction Treatment

Mckay, James R. -- University of Pennsylvania
Aftercare For Substance Abusers

Mclean Hospital -- Mclean Hospital
Using Drug Self-Administration In Rats To Evaluate D/A & Pharmacotherapies

Mclean, Hugh M. -- Hampton University
MIDARP At Hampton University

Meltzer, Peter C. -- Organix, Inc.
Discovery Of Novel Pharmacotherapies: Cocaine Dependence

Mendelson, Jack H. -- McLean Hospital, Belmont, MA
Biobehavioral Studies Of Narcotics Abuse

Mendelson, Jack H. -- McLean Hospital, Belmont, MA
Neurobiology Of Nicotine: Hormones And Behavior

Mendelson, John E. -- California Pacific Medical Center Research Institute
Dependence and Discontinuation Syndrome

Mendelson, John E. -- California Pacific Medical Center Research Institute
Clinical Pharmacology Of 3,4-Methylenedioxy Amphetamines

Meng, Ian D. -- University of New England
Trigeminal Mechanisms Of Cannabinoid Analgesia

Meredith, Gloria -- Rosalind Franklin University of Medicine & Science
Mechanisms Underlying Reward-Related Synaptogenesis

Mermelstein, Paul G. -- University of Minnesota Twin Cities
Nfat-Mediated Gene Expression and Striatal Plasticity

Metzler, Carol W. -- Oregon Research Institute
Evaluation Of A Video-Based Media Series To Promote Effective Parenting

Micevych, Paul E. -- University of California Los Angeles
Sex Steroid Activation Of Opioid Circuits In the CNS

Mickiewicz, Amanda L. -- Loyola University Chicago
Cellular Mechanisms In Opiate Reward-Mediated Learning

Miller, Gregory M. -- Harvard University Medical School
Molecular Probes For Specific Cocaine Recognition Sites

Miller, Gregory M. -- Harvard University Medical School
Trace Amine Receptors In Non Human Primates

Minugh, P. Allison -- MJ Data Corporation, Ltd
Data Documentation Database (D3): An Essential Research Tool

Mitchell, Suzanne H. -- Oregon Health & Science University
Reinforcer Efficacy: Measures and Neural Mechanisms

Mitty, Jennifer A. -- Miriam Hospital
DOT and Prevention For HIV(+) Persons Leaving Prison

Moeller, Frederick G. -- University of Texas Health Science Center Houston
Serotonin, Impulsivity, and Substance Abuse

Molina, Patricia E. -- Louisiana State University Health Science Center New Orleans
Cannabinoid Effects On HIV/AIDS

Morgan, Michael M. -- Washington State University
Cellular Mechanisms Of Opioid Tolerance

Morrell, Joan I. -- Rutgers The State University of New Jersey Newark
Maternal Rat Preferences For Pups Versus Cocaine

Mundel, Peter -- Mount Sinai School of Medicine of NYC
Synaptopodin: Biogenesis & Plasticity Of Spine Apparatus

Murphy, Sheigla B. -- Scientific Analysis Corporation
A Qualitative Study Of Women In Drug Markets

Murty Pharmaceuticals, Inc. -- Murty Pharmaceuticals, Inc.
Development & Manufacture Of Pharmaceutical Products For Addiction Treatment

Nader, Michael A. -- Wake Forest University Health Sciences
Chronic Stress and Cocaine Abuse In Female Monkeys

Nagarkatti, Prakash S. -- University of South Carolina at Columbia
Cannabinoid-Induced Apoptosis In T Cell Regulation

Nagy, Andras - Mt. Sinai Hospital-Samuel Lunenfeld Research Institute
Contribution To the Completion Of Comprehensive Mouse Knockout Resource

Neisewander, Janet L. -- Arizona State University
Neural Mechanism Of Drug-Seeking Behavior

Nelson, William M. -- Lochnels
Coping Power: Interactive Video Development

Nestler, Eric J. -- University of Texas Southwest Medical Center, Dallas
Molecular Studies Of Opiate and Cocaine Action In Brain

Nickerson, Lisa D. -- McLean Hospital, Belmont, MA
Novel Use Of fMRI To Study Substance Abuse Problems

Nicola, Saleem M. -- Ernest Gallo Clinic and Research Center
Nucleus Accumbens Processing Of Reward-Predictive Cues

Norman, Andrew B. -- P2d, Inc.
A Human Antibody As An Immunotherapy For Cocaine Abuse

Nunes, Edward V. -- Columbia University Health Sciences
Drug Abuse Treatment Development and Research Mentoring

Nunes, Edward V. -- New York State Psychiatric Institute
CU Partners: NY/Long Island Regional Node

Ochsner, Kevin N. -- Columbia University New York Morningside
The Neural Bases Of Affect Regulation In Drug Abuse

Oliveto Beaudoin, Alison -- University of Arkansas Medical Sciences Little Rock
Opioid Antagonist Discrimination: A Model Of Withdrawal

Olney, John W -- Washington University
Developmental Brain Damage By Drugs Of Abuse

Ondersma, Steven J. -- Wayne State University
Computer-Based Brief Intervention For Perinatal Drug, Alcohol, and Tobacco Abuse

Osawa, Yoichi -- University of Michigan at Ann Arbor
Inhibition and Inactivation Of No Synthase By Tobacco

Owens, Samuel Michael -- University of Arkansas Medical Sciences Little Rock
Antibody-Based Therapy For Methamphetamine Abuse

Pacula, Rosalie L. -- Rand Corporation
Economic Cost Of Drug Use and Abuse

Paladini, Carlos Antonio -- University of Texas San Antonio
Cellular Mechanisms In Cocaine Self-Administration

Pankratz, Melinda M. -- Pacific Institute For Research and Evaluation
Evidence-Based Prevention Curricula Implementation Over Time

Pankuch Alexander, Jessica -- Scripps Research Institute
Molecular Mechanism Of FAAH Substrate Recruitment

Pappas, George D. -- University of Illinois at Chicago
Analgesic Effects Of Adrenal Chromaffin Cell Transplants

Pare, Denis -- Gordon Research Conferences
2007 Amygdala In Health & Disease Gordon Research Conference

Paronis, Carol A. -- McLean Hospital, Belmont, MA
Opioids:Relative Reinforcing Strength and Dependence

Parsons, Jeffrey T. -- Hunter College
Patterns and Contexts Of Club Drug Abuse

Passetti, Lora L. -- University of Illinois Urbana-Champaign
12-Step Participation After Adolescent Treatment

Pasternak, Gavril W. -- Sloan-Kettering Institute For Cancer Research
Pharmacology Of Opioid Receptor Subtypes

Paulus, Martin P. -- University of California San Diego
Neurobiology Of Transition To Stimulant Dependence

Perry, David C. -- George Washington University
Chronic Nicotine Effects On Receptor Subtypes

Peterson, Phillip K. -- University of Minnesota Twin Cities
Dynorphin and Glial Cell Immunomodulation

Peterson, Phillip K. -- University of Minnesota Twin Cities
Modulation Of Cell-Mediated Immune Function By Opiates

Phillips, Paul E. -- University of Washington
Subsecond Dopamine Release During Compulsive Drug Taking

Pickel, Virginia M. -- Weill Medical College of Cornell University
EM-Transmitter Interactions Of Striatal Opioid Neurons

Pierce, Robert Christopher -- Boston University Medical Campus
Psychostimulant-Induced Craving and Toxicity

Pillsbury, Jolie Bain -- Sherbrooke Consulting, Inc.
A Teachable Method For Changing Unhealthy Behavior

Pleasure, Samuel J. -- University of California San Francisco
Defective Forebrain Development In Mutant Mice

Pollio, David E. -- Washington University
Housing, Homelessness, and Drug Abuse

Pomerleau, Ovide F. -- University of Michigan at Ann Arbor
Candidate Genes For Smoking In Related and Unrelated Individuals

Porrino, Linda J. -- Wake Forest University Health Sciences
Decision Making In Marijuana Users

Porrino, Linda J. -- Wake Forest University Health Sciences
Early Exposure To Stimulants As A Risk Factor For Substance Abuse

Potenza, Marc N. -- Yale University
Selegiline For Smoking Cessation

Premont, Richard T. -- Duke University
Dopamine Receptor Regulation By GRKs In Drug Abuse

Prochaska, Judith J. -- University of California San Francisco
Treating Tobacco Dependence In Inpatient Psychiatry

Proctor, Laura J. -- San Diego State University
Trajectories Of Adverse Childhood Experiences and Adolescent Substance Abuse

Pyne, Jeffrey M. -- University of Arkansas Medical Sciences Little Rock
Cost-Effectiveness Of Reducing Drug Treatment Barriers

Raiff, Bethany R. -- University of Florida
Sex Differences To Effects Of Nicotine On Responses Maintained By Environmental

Ramos-Ortolaza, Dinah L. -- University of Puerto Rico Rio Piedras
Role Of Neuropeptides In Cocaine-Seeking Behavior

Ramsay, Douglas S. -- University of Washington
Nitrous Oxide, Individual Differences, and Conditioning

Rao, Uma -- University of Texas Southwest Medical Center, Dallas
Stress and Risk For Substance Abuse In Adolescents

Read, Jennifer P. -- State University of New York at Buffalo
Trauma, Trauma Sequelae, and Substance Use In College

Reback, Cathy J. -- Friends Research Institute, Inc.
Voucher-Based Incentives In A Prevention Setting

Rebec, George V. -- Indiana University Bloomington
Neuropharmacology Of Drugs Of Abuse: Amphetamine

Regehr, Wade G. -- Harvard University Medical School
Retrograde Signaling By Endogenous Cannabinoids

Regents of University of California -- Regents of University of California
Nonclinical Adme Studies

Reggio, Patricia H. -- University of North Carolina Greensboro
Molecular Determinants For Cannabinoid Activity

Reichel, Carmela M. -- University of Nebraska Lincoln
Competition Between Conditioned Rewards: Novelty Vs. Cocaine

Research Triangle Insitute -- Research Triangle Insitute
Analytical Chemistry and Stability

Reti, Irving M. -- Johns Hopkins University
The Role Of NARP In Drug Abuse

Reynolds, Jessica L. -- State University of New York at Buffalo
Mechanisms Of Cocaine-Induced HIV-1 Infection In NHA

Ricaurte, George A. -- Johns Hopkins University
Studies Of Substituted Amphetamine Neurotoxicity

Richtand, Neil M. -- University of Cincinnati
Role Of D3 Dopamine Receptor In Behavioral Sensitization

Robertson, Andrew D. -- Keystone Symposia
Neurobiology Of Addiction

Robertson, Angela A. -- Mississippi State University
Hurricane Katrina Effects On Female Adolescent Offenders

Rohrbach, Louise A. -- University of Southern California
Impact Of Louisiana Hurricanes On Adolescent Substance Abuse

Roman, Paul M. -- University of Georgia
Adoption Of Innovations In Private A&D Treatment Centers

Rosenberg, Robert L. -- University of North Carolina Chapel Hill
Agonist-Driven Conformational Changes InACHrs

Rotrosen, John P. -- New York University School of Medicine
NIDA Clinical Trials Network - New York Node

Rotrosen, John P. -- New York University School of Medicine
Patient Feedback Effectiveness Study

Rowe, Cynthia L. -- University of Miami-Medical School
Family-Based Drug Services For Young Disaster Victims

Roy, Sabita -- University of Minnesota Twin Cities
Morphine, HIV Proteins, Wound Healing and Infection

Rush, Craig R. -- University of Kentucky
Stimulant Abuse Pharmacotherapy: Novel Antipsychotics

Rusyniak, Daniel E. -- Indiana University-Purdue University at Indianapolis
Ecstasy and the Dorsomedial Hypothalamus

Rutgers, University of New Jersey -- Rutgers, University of New Jersey
NIDSA Center For Genetic Studies

Rutherford, Megan J. -- University of Washington
Factors Related To Juvenile Drug Court Completion

Salom, David -- Polgenix, Inc.
Crystallization Of The Human Cannabinoid Type 2 Receptor

Samet, Jeffrey H. -- Boston Medical Center
Clinical Addiction Research and Education (CARE) Program

Samet, Jeffrey H. -- Boston Medical Center
Enhanced Linkage Of Drug Abusers To Primary Medical Care

Samuolis, Jessica -- National Health Promotion Associates
Lifeskills Training Elementary School Interactive CD-Rom

Schafer, William R. -- Medical Research Council
Analysis Of Touch Response & Habituation In C. Elegans

Schinke, Steven P. -- Columbia University New York Morningside
Drug Abuse Prevention: A Mother-Daughter Intervention

Schneider, Jay S. -- Thomas Jefferson University
Nicotine and Cognition In Parkinsonism

Schrott, Lisa M. -- Louisiana State University Health Science Center Shreveport
Drug Abuse Vulnerability: Role Of Development and Gender

Schulteis, Gerhard H. -- Veterans Medical Research Foundation, San Diego
Development Of Opiate Dependence--Neural Substrates

Schuman, Erin M. -- California Institute of Technology
Towards A Dendritic Proteome

Selby, Peter L. -- Selby, Peter L.
Maternal Opioid Treatment: Human Experimental Research

Self, David W. -- University of Texas Southwest Medical Center, Dallas
VTA Ionotropic Glutamate Receptors In Cocaine Addiction

Selley, Dana E. -- Virginia Commonwealth University
Transduction Mechanisms Of Opioid Agonist Efficacy

Shelton, Keith L. -- Virginia Commonwealth University
Discriminative Stimulus Effects Of Abused Inhalants

Shepard, Paul D. -- University of Maryland Baltimore Professional School
Dopamine Cell Impulse Flow, Reward and Schizophrenia

Shim, Joong-Youn -- North Carolina Central University
The CB1 Cannabinoid Receptor Activation By Protein Molecular Dynamics Simulations

Shoptaw, Steven -- University of California Los Angeles
UCLA Medication Development Unit For Stimulant Abuse

Sigmon, Stacey C. -- University of Vermont & State Agricultural College
Effective Treatment For Prescription Opioid Abuse

Silverman, Kenneth -- Johns Hopkins University
Employment-Based Addiction Pharmacotherapy

Simone, Donald A. -- University of Minnesota Twin Cities
Cannabinoid Modulation Of Hyperalgesia

Slesinger, Paul A. -- Salk Institute For Biological Studies
Kir 3 Channel Subunits In Drug Abuse With GABAb Agonists

Smeal, Stacy J. -- University of Utah
Mechanism Of Cannabinoid Incorporation In Hair

Smith, James E. -- Wake Forest University Health Sciences
Neurobiological Parameters Of Cocaine Reinforcement

Somoza, Eugene C. -- University of Cincinnati
Clinical Trials Network, Ohio Valley Node

Song, Zhao-Hui -- University of Louisville
Structure And Function Of CB2 Cannabinoid Receptor

Springer, J. Fred -- EMT Associates, Inc.
Web-Based Training On Core Skills For Evidence-Based Prevention Practice

Springer, J. Fred -- EMT Associates, Inc.
Development Of A Web-Based Analytic Tool For Strategic Prevention Planning

Spruston, Nelson P. -- Gordon Research Conferences
2006 Dendrites: Molecules, Structure and Function (Gordon Research Conference)

SRI International -- SRI International
Synthetic Peptides: Purity Det'm'n., Stability Testing & Quant

Stacy, Mark A. -- Duke University
Impulse Control Disorders In Parkinson's Disease Conference

Staley, Julie K. -- Yale University
Cognition, Tobacco Smoke and Nicotinic Receptor Occupancy

Stein, Michael D. -- Rhode Island Hospital, Providence, RI
Antidepressants During Office-Based Buprenorphine

Stella, Nephi -- University of Washington
Novel Monoacylglycerol Lipase

Stella, Nephi -- University of Washington
Genetics Of Endocannabinoid Biosynthesis and Inactivation

Stella, Nephi -- University of Washington
Cannabinoid Signaling System In Microglial Cell

Stevens, Craig W. -- OSU Center of Health Sciences
Functional Evolution Of Opioid Receptors

Stinchcomb, Audra L. -- University of Kentucky
Naltrexone Prodrugs For Transdermal Delivery

Stine, Susan M. -- Stine, Susan M.
Maternal Opioid Treatment: Human Experimental Research

Stone, T. Howard -- University of Texas Health Center at Tyler
Law & Ethics Of Drug Addiction Genetics Research

Stormshak, Elizabeth A. -- University Of Oregon
A Family Intervention For Adolescent Problem Behavior

Stout, Julie C. -- Indiana University Bloomington
Cognitive Modeling Of Risky Decisions In Drug Abusers

Strong, David R. -- Butler Hospital, Providence, RI
Mood Management Phone Counseling In Smoking Cessation

Sullivan, Mark D. -- University of Washington
Risks For Opioid Use and Abuse In Contrasting Chronic Pain Populations

Svensson, Camilla -- University of California San Diego
The Regulatory Role Of Spinal Lipoxins In Nociception

Swan, Gary E. -- SRI International
The Impact Of Smoking Cessation On Sleep

Swartz, James A. -- University of Illinois at Chicago
Jane Addams Substance Abuse Research Collaboration

Szapocznik, Jose -- University of Miami-Medical School
Florida Node Of the Drug Abuse Clinical Trials Network

Tanner, T. Bradley -- Clinical Tools, Inc.
Medical Student Training On Buprenorphine and Opioid Dependence

Tapert, Susan F. -- Veterans Medical Research Foundation, San Diego
fMRI and Cognition In Adolescent Cannabis Users

Taxman, Faye S. -- Virginia Commonwealth University
Action Research To Advance Drug Treatment In the CJS

Teicher, Martin H. -- McLean Hospital, Belmont, MA
Early Stress, PTSD, and the Neurobiology Of Addiction

Teplin, Linda A. -- Northwestern University
Drug Use, Disorder & HIV/AIDS Risk In Juvenile Justice Youth:A Longitudinal Study

Thatcher, Dawn L. -- University of Pittsburgh at Pittsburgh
Adult Neurobehavioral Outcomes Of Adolescent Drug Abuse

Thayer, Stanley A. -- University of Minnesota Twin Cities
HIV Neurotoxicity-Mechanism & Modulation By Cannabinoids

Thomas, Mark J. -- University of Minnesota Twin Cities
Synaptic Plasticity In Animal Models Of Addiction

Thompson, Barbara L. -- Vanderbilt University
Developmental Consequences Of In Utero Cocaine

Thompson, Sanna J. -- University of Texas Austin
Family-Based Substance Use Treatment For Runaway Youth

Tidey, Jennifer W. -- Brown University
Biological and Behavioral Mechanisms Of Smoking In Schizophrenia

Tietz, Elizabeth I. -- University of Toledo Health Sciences Campus
Benzodiazepine-Induced Glutamate Receptor Plasticity

Toll, Lawrence R. -- SRI International
Subtype-Selective Nicotinic Receptor Ligands As Smoking Cessation Pharmacotherapy

Tranel, Daniel T. -- University of Iowa
Drug Abuse, Social Decision-Making, and Sex-Related Functional Brain Asymmetry

Traynor, John R. -- University of Michigan at Ann Arbor
Opioid Receptor Mechanisms

Tucker, Joan S. -- Rand Corporation
Drugs Use, Social Context, and HIV Risk In Homeless Youth

Tueckmantel, Werner -- Acenta Discovery, Inc.
Nicotinic Ligands As Smoking Cessation Agents

Tull, Matthew T. -- University of Maryland
Predictors Of Drug Related Attentional Biases Among Crack/Cocaine Users With PTSD

University of Utah -- University of Utah
Quantitation Of Drugs Of Abuse By GC/MS

University of Miami -- University of Miami
The National Hispanic Science Network On Drug Abuse

University Of Mississippi -- University Of Mississippi
Production, Analysis & Distribution Of Cannabis & Marijuana

Unterwald, Ellen M. -- Temple University
Regulation Of Delta Opioid Receptor Function By Cocaine

Valdez, Avelardo -- University of Houston
Substance Use and Other Health Consequences Among Katrina Evacuees In Houston

Van Bockstaele, Elisabeth J. -- Thomas Jefferson University
Opioid Modulation Of the Coeruleo-Cortical Pathway

Van Bockstaele, Elisabeth J. -- Thomas Jefferson University
Modulation Of Norepinephrine By Cannabinoids

Van Den Oord, Edwin -- Virginia Commonwealth University
In Silico Genome Scan With High-Throughput Addiction Related Phenotypes In Mice

Vanderah, Todd W. -- University of Arizona
Brain Stem Mechanisms Of Opioid Induced Pain

Vanderschuren, Louk J.M.J. -- University Medical Center Utrecht
Social Play Behavior In Periadolescent Rats In Relation To Later Drug Abuse

Vaughan, Roxanne A. -- University of North Dakota
Phosphorylation and Regulation Of Dopamine Transporters

Vezina, Paul R. -- University of Chicago
Nicotine Exposure: Molecular To Behavioral Consequences

Vilim, Ferdinand S. -- Mount Sinai School of Medicine of NYU
Neural Basis Of Behavior Priming: Induction and Memory

Virginia Commonwealth University -- Virginia Commonwealth University
Preclinical Abuse Liability and Medications Discovery Testing

Virginia Commonwealth University -- Virginia Commonwealth University
Medication Discovery Using Rat Models Of Relapse To Drug Self Administration

Virk, Michael S. -- Oregon Health & Science University
Agonist Specific Mu-Opioid Receptor Regulation

Vlahov, David -- New York Academy of Medicine
The HIV Risk Behavior and the Urban Environment

Voigt, Robin M. -- Loyola University Chicago
GABAbeta Regulation Of Meth-Induced Associative Learning

Von Korff, Michael R. -- Center For Health Studies
Long-Term Opioid Management Of Chronic Pain: Trends and Risks

Von Zastrow, Mark E. -- Gordon Research Conferences
2007 Molecular Pharmacology Gordon Research Conference

Vorhees, Charles V. -- Children's Hospital Medical Center, Cincinnati
Developmental Effects Of Methamphetamine-Like Stimulants

Vorhees, Charles V. -- Children's Hospital Medical Center, Cincinnati
Effects Of Neonatal On Brain and Behavior

Vujanovic, Anka A. -- University of Vermont & State Agricultural College
Nicotine Withdrawal and Panic Responding

Wade, Carrie A. -- University of Minnesota Twin Cities
Neuropharmacology Of Neuropathic Pain and Addiction

Wagner, John J. -- University of Georgia
Cocaine-Induced Metaplasticity In the Hippocampus

Wakschlag, Lauren S. -- University of Illinois at Chicago
Prenatal Smoking and Patterns Of Youth Problem Behavior

Walker, J. Michael -- Indiana University Bloomington
Role Of Endogenous Vanilloids and Cannabinoids In Pain

Walsh, Sharon L. -- University of Kentucky
Evaluation Of Novel Treatments For Stimulant Dependence

Wang, Jia B. -- University of Maryland Baltimore Professional School
MOR Phosphorylation In Opiod Tolerance and Dependence

Wang, Qiang -- University of Missouri Kansas City
Metabotropic Glutamate Regulation Of Amphetamine Action

Wang, Zuoxin -- Florida State University
Dopamine Regulates Drug and Social Reward Interactions

Ward, Kenneth D. -- University of Memphis
Population-Based Assessment Of Post-Katrina Smoking Relapse

Waterhouse, Barry D. -- Drexel University
Locus Coeruleus Function and Methylphenidate Action

Watkins, Linda R. -- University of Colorado at Boulder
Pain Facilitation Via Neuron-To-Glia Signaling

Weerts, Elise M. -- Johns Hopkins University
Behavioral Pharmacology and GHB Physical Dependence

Wei, Li-Na L. -- University of Minnesota Twin Cities
Studies Of the Mouse Kappa Opioid Receptor Gene

Weisner, Constance M. -- University of California San Francisco
Integrated Drug and Medical Care-Cost and Effectiveness

Weisner, Constance M. -- University of California San Francisco
Course Of Problems In Adolescent Drug Treatment Intakes

Weiss, Friedbert -- Scripps Research Institute
Novel Treatments For Cocaine Dependence

Weiss, Roger D. -- McLean Hospital, Belmont, MA
CTN: Harvard University Northern New England Node

Weissman, Myrna M. -- Columbia University Health Sciences
Children At High and At Low Risk For Depression

Wheeler, Robert A. -- University of North Carolina Chapel Hill
The Nucleus Accumbens and Relative Reward

Whistler, Jennifer L. -- Ernest Gallo Clinic and Research Center
Role Of Opioid Receptor Trafficking In Tolerance and Dependence

Wiederhold, Mark D. -- Virtual Reality Medical Center
Low-Cost FMRI-Safe Virtual Reality Glasses

Wiley, Jenny L. -- International Cannabinoid Research Society
ICRS Symposium On the Cannabinoids

Williams, John T. -- Oregon Health & Science University
Chronic Morphine: Regulation Of Ion Conductances

Williams, John T. -- Oregon Health & Science University
Cocaine Effecs On Single Neurons

Winsauer, Peter J. -- Louisiana State University Health Science Center
New Orleans Effects Of Chronic THC In Adolescence

Wolf, Marina E. -- Rosalind Franklin University of Medicine & Science
Glutamate Transmission and Behavioral Sensitization

Wolf, Marina E. -- Rosalind Franklin University of Medicine & Science
Glutamate and Psychostimulant-Induced Neuroadaptations

Wong, Frank Y. -- Georgetown University
Sexuality, HIV/Drug In 3 Groups Of Asian/Gay/Bi Men/MSM

Woods, James H. -- University of Michigan at Ann Arbor
Development Of Esterases For the Treatment Of Cocaine Overdose and Abuse

Woody, George E. -- University of Pennsylvania
Delaware Valley Node Of the Clinical Trials Network

Woolverton, William L. -- University of Mississippi Medical Center
Self-Administration Of Drug Combinations: Polydrug Abuse

Worley, Paul F. -- Johns Hopkins University
Effector IEG, Homer and Drug Addiction

Worley, Paul F. -- Johns Hopkins University
Analysis Of A Novel Cocaine Induced Immediate Early Gene

Wu, Christine C. -- University of Colorado Denver/Health Sciences Center Aurora
Proteomic Tools For the Comprehensive Analysis Of Dopamine Transporter Topology

Wu, Elwin -- Columbia University New York Morningside
Service Use, ATI Program Outcomes, and Pro-Social Change

Wu, Li-Tzy -- Duke University
Hallucinogen Use: Onset and Abuse/Dependence

Wu, Ping -- Columbia University Health Sciences
Ecstasy "Epidemic" and Youth: Trends, Comorbidity, Risk and Protective Factors

Wu, Z. Helen -- University of Texas Medical Branch Galveston
Effects Of Stressors On Drug Use In Young, Poor Women

Xenotech, LLC - Xenotech, LLC
In Vitro Metabolism & Metabolite Quantification

Xian, Hong -- Washington University
Environmental Risks For Smoking: A Genetically Informed Children Of Twins Design

Xu, X. Z. -- University of Michigan at Ann Arbor
Mechanisms Of Nicotine-Induced Behaviors

Xu, Xiangmin -- Salk Institute For Biological Studies
Local Connections and In Vivo Physiology Of Inhibitory Cortical Neurons

Yaksh, Tony L. -- University of California San Diego
The Pharmacology Of Spinal Analgesics

Yamamoto, Bryan K. -- Boston University Medical Campus
Methamphetamine Toxicity and Corticostriatal Glutamate

Yano, Motoyo -- Rosalind Franklin University of Medicine & Science
Methylphenidate-Induced Gene Expression In the Cortex

Yu, John-Paul J. -- University of Illinois Urbana-Champaign
Treatment and Control Of Mycobacterial Infections

Zemlan, Frank -- P2d, Inc.
Cocaine Therapeutic: Pd2007

Zhang, Heping -- Yale University
Statistical Methods In Genetic Studies Of Substance Use

Zhang, Heping -- Yale University
Methodological Research On Substance Use

Zhao, Min -- Shanghai Mental Health Center
Gender Difference Of HIV Risks Among IDUs In China

Zweifel, Larry S. -- University of Washington
Genetic Dissection Of Brain Reward Circuits


Index

Research Findings

Program Activities

Extramural Policy and Review Activities

Congressional Affairs

International Activities

Meetings and Conferences

Media and Education Activities

Planned Meetings

Publications

Staff Highlights

Grantee Honors



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