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Director's Report to the National Advisory Council on Drug Abuse
February, 1996


Publications


Drug Abuse Among Racial/Ethnic Minorities NCADI #BKD180
Discusses the nature of drug abuse among minorities by summarizing from a variety of surveys the most current data available on this issue. Data are presented on the prevalence, morbidity, mortality, and adverse consequences of drug use among racial/ethnic populations.

Hair Testing for Drugs of Abuse: International Research on Standards and Technology NCADI #BKD181
Provides an overview of the state-of-the-art research and results related to some of the more controversial aspects of hair analysis for drugs of abuse.

Remotely Science -Video & Teacher's Packet NCADI #PHD715 (packet), NCADI #VHS49 $8.50 (video)
The "Remotely Science" video, shows elementary school students that addiction research is exciting and fun. The teacher's packet, designed to accompany the video, contains 1 teacher's guide and 50 full-color student magazines. The magazine is a useful tool to help teach students about the effects of drugs on the brain by providing fun activities to help students find answers to questions that arise from the video. The 12-page teacher's guide gives suggestions on how to use the video and the magazine with students.

National Survey Results from the Monitoring the Future Study, 1975-1994: Vol I NCADI #BKD179
A compilation of data on drug abuse by the Nation's 8th, 10th, and 12th grades, comparing data from 1975 through 1994. Discusses the prevalence and impact of drug abuse among secondary school students.


Research Monographs


Membranes and Barriers: Targeted Drug Delivery - Research Monograph 154 (1995) NCADI #M154
Discusses the ability of drugs to effectively cross the various membrane barriers and reach the receptors which allow the drugs to produce biological effect(s). Discusses the modern drug design techniques that now make it possible to design drugs that are selectively delivered to a specific target. Mechanisms of drug transport are also discussed in terms of prodrugs, stable drugs, peptidomimetics, etc.

Reviewing the Behavioral Science Knowledge Base on Technology Transfer - Research Monograph 155 (1995) NCADI #M155
Discusses comprehensive approaches to technology transfer from several disciplines, including behavioral science. Discusses the development of technology transfer strategies, setting them in the larger context of partnership efforts with community constituencies and overall changes in health care and information technology.

Adolescent Drug Abuse: Clinical Assessment and Therapeutic Interventions - Research Monograph 156 (1995) NCADI #M156
Presents an overview of clinical assessment procedures, service delivery strategies, and therapeutic interventions designed specifically for youth. Special attention is given to drug-related medical problems, cultural issues, and family involvement.

Qualitative Methods in Drug Abuse and HIV Research - Research Monograph 157 (1995) NCADI #M157
Reviews current applications of qualitative methods in drug abuse and HIV/AIDS prevention research. Emphasis is on the use of innovative ethnographic methods of accessing hidden populations, target sampling, identifying drug use and HIV/AIDS risk behaviors, developing culturally appropriate risk reduction messages, implementing interventions, and evaluating program results.

Biological Mechanisms and Perinatal Exposure to Drugs - Research Monograph 158 (1995) NCADI #M158
Reviews the current research findings in the area of perinatal exposure to abused drugs and its impact on various biological systems during the developmental period.

Dr. Meyer Glantz published a description of an innovative substance abuse treatment for use with the elderly in "Cognitive Therapy with Elderly Alcoholics" in T. Beresford and E. Gomberg (Eds.), Alcohol and Aging, New York: Oxford University Press, 1995.

The entire December 1995 issue of Neuropsychopharmacology (Volume 13, Number 4) was devoted to the publication of 8 peer reviewed articles which were engendered by 12 presentations at the October 1994 NIDA/Medications Development Division (MDD). The effects of NMDA receptor antagonists on opiate tolerance and withdrawal is summarized.
Drs. Herman, Vocci, and Bridge of MDD contributed an article entitled "The Effects of NMDA Receptor Antagonists and Nitric Oxide Synthase Inhibitors on Opioid Tolerance and Withdrawal".

Li, Shou-Hua; Chiang, Nora C.; Tai, Betty C.; Marschke, Charles K.; Hawks, Richard L. "Quantitative vs. Qualitative Urinalysis for Benzoylecgonine in Clinical Trials for the Assessment of Cocaine Use" Psychopharmacology Bulletin, pp. 671-679, December, 1995.

Margolin, Arthur; Kosten, Thomas R.; Avants, S. Ketty; Wilkins, Jeffry; Ling, Walter; and Beckson, Mace; Arndt, Isabelle; Cornish, James; Li, Shou-Hua; Bridge, Peter, and Ascher, John A., "A Multi-Center Trial of Buproprion for Cocaine Dependence in Methadone Maintained Patients" Drug and Alcohol Dependence, pp. 125-131, December, 1995.

Pilotte, NS, Sharpe, LG, Rountree, SD & Kuhar, MJ, "Cocaine Withdrawal Reduces Dopamine Transporter Binding in the Shell of the Nucleus Accumbens". Synapse, 22: pp. 87-92, 1996.

Healy TEJ, Cohen PJ. "A Practice of Anaesthesia", Edward Arnold, London.

Dr. Peter Hartsock published a letter to the editor in the November, 1995 American Journal of Public Health dealing with syringes in eastern Europe.

Dr. Harry Haverkos published an article entitled "Identifying Substance Abuse in Primary Care" in the American Family Physician, 52: pp. 2029-2035, 1995.

Dr. Jack Henningfield published a review of "Nicotine Medications for Smoking Cessation" in the November edition of the New England Journal of Medicine.


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