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NIDA Home > Publications > Director's Reports > February, 2008 Index    

Director's Report to the National Advisory Council on Drug Abuse - February, 2008



Publications

NIDA Publications

Community Monitoring Systems: Tracking and Improving the Well-Being of America's Children and Adolescents
NIH Pub. No.: 07-5852

Monitoring the well-being of children and adolescents is a critical component of efforts for preventing behavioral, psychological and health problems and promoting successful development. This document provides valuable information for community leaders, policy makers and practitioners in developing and using monitoring systems for prevention planning.

Epidemiologic Trends in Drug Abuse - Community Epidemiology Work Group - Volume I - June 2007 [pdf]
NIH Pub No.: 08-6200A-5881A

This report provides an ongoing assessment of drug abuse in major metropolitan areas of the United States with the purpose of keeping both public and private sector policymakers and researchers informed with current and accurate data.

Epidemiologic Trends in Drug Abuse - Community Epidemiology Work Group - Volume II - June 2007
NIH Pub. No. 08-6204A

This report provides an in-depth analysis of the epidemiologic trends and special reports for a limited audience made up primarily of drug abuse researchers who utilize this volume to identify potential areas for further research.

NIDA NOTES

NIDA NOTES, Vol. 21, No. 4
NIH 07-3478

The lead story looks at the neuropeptide orexin and links to the reward system. The Director's Perspective reports on NIDA's role in the NIH obesity task force, and a NIDA at Work feature reports on the Division of Clinical Neuroscience and Behavioral Research. Research reports look at endorphin's role in inhibiting reward from morphine and nicotine in rats, gene experiments that confirm cocaine exposure regulates certain genes, and a study linking anabolic steroids to brain changes in mice. The NIDA Notes Reference Article provides a primer on the impacts of drugs on neurotransmission.

CTN-Related Publications

Eight editions of the CTN Bulletin Board were distributed. The Bulletin Board is an electronic report on the progress of the protocols, committees, and node activity in the CTN.

International Publications

NIDA Notes Features International Supplement on Drug Abuse and HIV/AIDS
NIDA Notes 2007; 21(4):19 focused on the NIDA International Program peer-reviewed supplement to Drug and Alcohol Dependence [2006; 82(S1)], Drug Abuse and HIV/AIDS: International Research Lessons and Imperatives.

NIDA International Program E-News Letter
November 2007 - This issue announced four research projects funded by the U.S. - Netherlands Binational Agreement, the results of DISCA-supported research on methamphetamine and the blood brain barrier, IP activities at the American Association for the Treatment of Opioid Dependence Conference and the Society for Neuroscience Meeting, and the call for papers for the second round and announcement of recipients of the first NIDA/CICAD Competitive Research Program awards. The issue also provides links to the online registration and abstract submission sites for the 2008 NIDA International Forum.

September 2007 - The September IP E-News Letter announced FY 2008 funding for the Program Announcement on International Research Collaborations to Study HIV/AIDS and Drug Abuse, the results of U.S. - Spain joint research that supported community reinforcement approach plus vouchers in treating Spanish cocaine abusers, and the IP publication of an international consensus report setting guidelines for future international research into driving under the influence of drugs.

Other Publications

Pickering, R.P., Grant, B.F., Chou, S.P. and Compton, W.M. Are Overweight, Obesity, and Extreme Obesity Associated with Psychopathology? Results from the National Epidemiologic Survey on Alcohol and Related Conditions. The Journal of Clinical Psychiatry 68, pp. 998-1009, 2007.

Goldstein, R.B., Compton, W.M., Pulay, A.J., Ruan, W.J., Pickering, R.P., Stinson, F.S., and Grant, B.F. Antisocial Behavioral Syndromes and DSM-IV Drug Use Disorders in the United States: Results from the National Epidemiologic Survey on Alcohol and Related Conditions. Drug and Alcohol Dependence 90, pp. 145-158, 2007.

Robertson, E.B. and Compton, W.M . Prevention of Drug Use and Drug Use Disorders. In: Wallace, R.B. and Kohatsu, N., (eds.) Public Health and Preventive Medicine, fifteenth edition, pp. 1013 - 1023, 2007.

Jenkins, R.A. Challenges in Engaging Community Participation in HIV Prevention Research (Invited editorial). Progress in Community Health Partnerships, 1, pp. 117-119, 2007.

Jenkins, R.A. Toward a Broader View of Research Ethics. [Review of the book, "Research Ethics for Social Scientists"]. PsycCRITIQUES--Contemporary Psychology: APA Review of Books 52 (No. 33) Article 50, August 15, 2007.

Lopez, M.F., Compton, W.M., Grant, B.F., and Breiling, J.P. Dimensional Approaches in Diagnostic Classification: A Critical Appraisal. Int. J. Methods Psychiatr. Res. 16 Suppl 1, S6-S7, 2007.

Liberman, A.M. (Ed.) The Long View of Crime: A Synthesis of Longitudinal Research. New York: Springer, 2008.

Gordon, H.W. Sleep, Circadian Rhythm, and Drug Abuse (Editorial) 2007, The Scientific World, 7(s2), pp. 191-193, 2007.

Bardo, M.T., and Schnur, P. The Motivational Impact of Nicotine and its Role in Tobacco Use: Final Comments and Priorities. In R. Bevins (Ed.), The Nebraska Symposium on Motivation, 2007.

Wetherington, C.L. Sex-gender Differences in Drug Abuse: A Shift in the Burden of Proof. Experimental and Clinical Psychopharmacology, 15, pp. 411-417, 2007. (This article appeared as the lead article in the issue.)

Volman, S.F. Evaluating the Functional Importance of Neuroadaptions in Addiction. ScientificWorld Journal, 7 (S2), pp. 4-8, 2007.

Wu, D.Y., and Saterlee, J.S. Decoding Drug Abuse in Noncoding RNA? Scientific World Journal 7, pp. 142-145, 2007.

Lawrence, D.M., Thomas, D.A., and Wu, D.Y. Glial Cells and the Neurobiology of Addiction. ScientificWorld Journal 7(S2), pp. 86-88, 2007.

Satterlee, J.S., Barbee, S., Jin, P., Krichevsky, A., Salama, S., Schratt, G., Wu, D.Y. Noncoding RNAs in the Brain. J. Neurosci. 27(44), pp. 11856-11859, 2007.

Thomas, Y.F., Schnur, P., and Iguchi, M.Y. Behavioral and Economic Perspectives in Drug Abuse Research. Drug and Alcohol Dependence, 90, Supplement 1, S1-S3, 2007.

Shurtleff, D., Rutter, J.L., Ramsey, K.E., Craig, D.W., and Stephan, D.A. The Nuts and Bolts of Gene Array Technology and its Application to Drug Abuse Research. Drug and Alcohol Dependence 91, pp. 102-106, 2007.

Shurtleff, D., and Ferre, S. Sponsor's Foreword. Scientific World Journal. 7(S2), pp. 1-3, 2007.

Drs. David Shurtleff and Sergi Ferre co-edited a special issue of the ScientificWorld Journal, 2007 Nov 2:7 (S2) entitled Frontiers in Addiction Research. The mini-reviews in this special issue were written by speakers from the NIDA-supported satellite meeting, "Frontiers in Addiction Research," held at the 2007 annual meeting of Society for Neuroscience (SfN), and from NIDA-supported symposia presented during the annual SfN meeting itself. The editorials in the issue, provided by symposia chairs, summarize the science and highlight research gaps and opportunities captured by the various symposia.

Ivan Montoya and Douglas Ziedonis were co-editors of two issues (Volume 3, issues 3 and 4) of the Journal of Dual Diagnosis about Comorbid Nicotine Dependence and Schizophrenia.

Ziedonis, D., Montoya I. Tobacco Dependence Amongst Individuals with Schizophrenia: A Public Health Crisis and an Opportunity for Bidirectional Translational Research. Journal of Dual Diagnosis, Volume 3(3/4), pp. 3-7, 2007.

Montoya, I., Vocci, F. Medications Development of the Treatment of Nicotine Dependence in Individuals with Schizophrenia. Journal of Dual Diagnosis. Volume 3(3/4), pp. 113-150, 2007.

Khalsa, J.H. and Vocci, F. Management of HIV/HCV co-infected Drug Substance Abusers, in Management of Medical Disorders Associated with Drug Abuse and Addiction, eds. G. Barbaro, F. Nava, A. Lucchini and G. Barbarini, Nova Publishers, Italy, November 2007.

Montoya, I.D., and Vocci, F. Medications Development for the Treatment of Nicotine Dependence in Individuals with Schizophrenia. J Dual Diagnosis 3(3/4), pp. 113-150, 2007.

Khalsa, J., and Vocci, F.J. Management of HIV/HCV Coinfection in Drug Abusers. In: Management of Medical Disorders Associated with Drug Abuse and Addiction, eds. Barbaro, G, Nava F, Lucchini A, Barbarini G., Nova Publishers, pp. 161-186, 2007.

Vocci, F.J. Preface to Book: Management of Medical Disorders Associated with Drug Abuse and Addiction, eds. Barbaro, G, Nava F, Lucchini A, Barbarini G., Nova Publishers, 2007.

Vocci, F. Can Replacement Therapy Work in the Treatment of Cocaine Dependence? And What Are We Replacing Anyway? Addiction 102, pp. 1888, 2007. Cadet, J.L and Krasnova, I.N. Interactions of HIV and Methamphetamine: Cellular and Molecular Mechanisms of Toxicity Potentiation. Neurotoxicology Research 12(3), pp. 181-204, 2007.

Goldberger, B.A., Grahan, N.A., Nelson, S.J., Cadet, J.L., and Gold, M.S. A Marked Increase in Cocaine-related Deaths in the State of Florida: Precursor to an Epidemic? Journal of Addictive Diseases 26(3), pp. 113-116, 2007.

Krasnova, I.N., Li, S.M., Wood, W.H., McCoy, M.T., Prabhu, V.V., Becker, K.G., Katz, J.L. and Cadet, J.L. Transcriptional Responses to Reinforcing Effects of Cocaine in the Rat Hippocampus and Cortex. Genes Brain Behavior, July 19, 2007.

Martin, B., Pearson, M., Kebejian Golden, E., Keselman, A., Bender, M., Carlson, O., Egan, J., Ladenheim, B., Cadet, J.L., Becker, K.G., Wood, W., Duffy, K., Vinayakumar, P., Muudsley, S. and Mattson, M.P. Sex-dependent Metabolic, Neuroendocrine, and Cognitive Responses to Dietary Energy Restriction and Excess. Endocrinology 148(9), pp. 4318-4333, 2007.

Vahabzadeh, M., Lin, J.-L., Mezghanni, M., Contoreggi, C., and Leff, M.A. Clinical Recruiting Management System for Complex Multi-Site Clinical Trials Using Qualification Decision Support Systems. Proc. AMIA Annual Symposium on Biomedical and Health Informatics: From Foundations to Applications to Policy (American Medical Informatics Association-2007), pp. 1141, 2007.

Othman, A.A., Newman, A.H., and Eddington, N.D. Applicability of the Dopamine and Rate Hypotheses in Explaining the Differences in Behavioral Pharmacology of the Chloro-Benztropine Analogs: Studies Conducted Using Intracerebral Microdialysis and Population Pharmacodynamic Modeling. J. Pharmacol. Exp. Ther. 322(2), pp. 760-769. E-pub May 22, 2007.

Grundt, P., Prevatt, K.M., Cao, J., Taylor, J., Floresca, C.Z., Choi, J.-K., Jenkins, B.G., Luedtke, R.R., and Newman, A.H. Heterocyclic Analogues of N-(4-(4-(2,3-Dichlorophenyl)piperazin-1-yl)-butyl)-aryl-carboxamides with Functionalized Linking Chains as Novel Dopamine D3 Receptor Ligands: Potential Substance Abuse Therapeutic Agents. J. Med. Chem. 50, pp. 4135-4146, 2007.

Syed, S.A., Newman, A.H., and Eddington, N.D. Population Pharmacokinetics, Brain Distribution and Pharmacodynamics of 2nd generation Dopamine Transporter Selective Benztropine Analogs Developed as Potential Substitute Therapeutics for Treatment of Cocaine Abuse. J. Pharm. Sci. e-pub September 19, 2007.

Loland, C.J., Desai, R.I., Gerstbrein, K., Zou, M.-F., Cao, J., Grundt, P., Sitte, H.H., Newman, A.H., Katz, J.L. and Gether, U. Relationship Between Conformational Changes in the Dopamine Transporter and Cocaine-like Subjective Effects of Uptake Inhibitors. Mol. Pharmacol. e-pub October 31, 2007.

Spiller, K., Xi, Z.-X., Peng, X.-Q., Newman, A.H., Ashby, C.R., Heidbreder, C., Gaal, J., and Gardner, E.L. The Putative Dopamine D3 Receptor Antagonists SB 277011A, NGB 2904 or BP 897 Inhibit Methamphetamine-Enhanced Brain Stimulation Reward in Rats. Psychopharmacology, e-pub November 6, 2007.

Rothman, R.B., Baumann, M., Prisinzano, T.E., and Newman, A.H. Dopamine Transport Inhibitors Based on GBR12909 and Benztropine as Potential Medications to Treat Cocaine Addiction. Biochem. Pharmacol., Special Issue on Addiction, invited review. E-pub August 9, 2007.


Index

Research Findings

Program Activities

Extramural Policy and Review Activities

Congressional Affairs

International Activities

Meetings and Conferences

Media and Education Activities

Planned Meetings

Publications

Staff Highlights

Grantee Honors

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