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Director's Report to the National Advisory Council on Drug Abuse - February, 2007



Program Activities

New NIDA PAs and RFAs

On August 3, 2006, NIDA/CCTN released RFA-DA-07-001, Announcement of a Limited Competition of THE NATIONAL DRUG ABUSE TREATMENT CLINICAL TRIALS NETWORK (U10). This RFA announced a limited competition for competitive renewal applications from established clinical investigators to participate in the National Drug Abuse Treatment Clinical Trials Network (CTN). The competition was restricted to only those institutions that currently house an existing, active Node in the CTN. Six applications were received by the November 28, 2006 receipt date. Initial peer review is planned for February/March 2007.

On September 18, 2006, NIDA issued a Program Announcement (PA) entitled NIDA Research Education Grants in Drug Abuse and Addiction (R25) (PAR-06-550). The NIDA Research Education grant is a flexible and specialized mechanism designed to foster the development of drug addiction researchers through creative and innovative educational programs. Programs that focus on preparing researchers in cross-disciplinary integration and/or translational research of neuroscience, basic behavioral, prevention, clinical, treatment, and services research are particularly encouraged.

On December 6, 2006, NIDA issued a PA entitled Drug Abuse Prevention Intervention Research (R01) (PA-07-110). The goals of this Funding Opportunity Announcement (FOA) are to encourage investigstions of cognitive, behavioral, and social processes as they relate to: 1) the development of novel drug abuse prevention approaches; 2) the efficacy and effectiveness of newly developed and/or modified prevention programs; and 3) the processes associated with the selection, adoption, adaptation, implementation, sustainability and financing of empirically validated intervention; and 4) methodologies appropriate for studying complex aspects of prevention science.

On December 7, 2006, NIDA issued a PA entitled MDMA: Research Areas Needing More Emphasis (R01) (PA-07-112). Through this FOA, NIDA solicits grant applications from institutions/organizations that propose to focus on specific areas of MDMA research, across all research disciplines urgently needing attention.

On December 7, NIDA issued a PA entitled Health Services Research on Practice Improvement Utilizing Community Treatment Programs within the National Drug Abuse Clinical Trials Network (CTN) (R01) (PA-07-1143). This FOA solicits health services research in conjunction with NIDA's Clinical Trials Network (CTN). The CTN is a research partnership between more than 150 community treatment programs (CTPs) and drug abuse researchers in multiple sites across the country. With its extensive network of providers servicing diverse populations of drug users, the CTN provides an infrastructure for the investigation of (a) systems-level factors that facilitate practice improvement in community treatment programs and (b) new research tools to facilitate higher quality health services research on practice improvement in drug abuse treatment.

On December 7, 2006, NIDA issued a PA entitled Drug Abuse as a Cause, Correlate or Consequence of Criminal Justice Related Health Disparities Among African Americans (R01) (PA-007-114). This FOA solicits Research Project Grants (R01) applications from institutions/organizations that propose to conduct epidemiologic, prevention, treatment and services research on criminal justice related health disparities among African Americans as it relates to drug abuse and addiction.

On December 8, 2006, NIDA issued a PA entitled Inhalant Abuse: Supporting Broad-Based Research Approaches (R01) (PA-07-117). The goal of this PA is to encourage research on all aspects of inhalant abuse (i.e., epidemiology; prevention, treatment and service delivery; antecedents, consequesnces and neurobiological mechanisms).

On December 8, 2006, NIDA issued a PA entitled Prescription Drug Abuse (R01) (PA-07-123). The purpose of this FOA is to encourage research aimed at reducing prescription drug abuse while supporting appropriate medical use of therapeutic agents with abuse liability. A range of research is needed to combat prescription drug abuse--from specifying the extent and nature of the problem (including health and social consequences) and identifying their determinants, to discovering effective clinical practices that identify those at risk and designing and disseminating prevention and treatment interventions.

On December 8, 2006, NIDA issued a PA entitled Epidemiology of Drug Abuse (R01) (PA-07-118). This FOA is intended to support research projects that address (1) drug use patterns and trends within and across populations; (2) interplay of social interactions, social environment, structural context with individual behavioral characteristics and genetic vulnerability; (3) the phenotypic heterogeneity of drug abuse; (4) causal mechanisms leading to onset, maintenance, and remittance of drug abuse as well as protective mechanisms that reduce the risk of drug abuse; and (5) drug abuse over the life course, including developmental processes that influence drug use trajectories and behavioral, health and social consequences of drug abuse.

On December 14, 2006, NIDA issued a PA entitled Functional Genetics and Genomics of Drug Addiction (R01) (PA-07-166). This FOA encourages basic functional genomic research in two areas: 1) functional validation to determine which candidate genes/variants have an authentic role in addictive processes, and 2) detailed elucidation of the molecular pathways and processes modulated by candidate genes/variants, particularly for those genes with an unanticipated role in addiction. This FOA will utilize the R01 grant mechanism.

On December 14, 2006, NIDA issued a PA entitled Functional Genetics and Genomics of Drug Addiction (R03) (PA-07-168). This FOA encourages basic functional genomic research in two areas: 1) functional validation to determine which candidate genes/variants have an authentic role in addictive processes, and 2) detailed elucidation of the molecular pathways and processes modulated by candidate genes/variants, particularly for those genes with an unanticipated role in addiction. This FOA will utilize the R03 grant mechanism.

On December 14, 2006, NIDA issued a PA entitled Functional Genetics and Genomics of Drug Addiction (R21) (PA-07-167). This FOA encourages basic functional genomic research in two areas: 1) functional validation to determine which candidate genes/variants have an authentic role in addictive processes, and 2) detailed elucidation of the molecular pathways and processes modulated by candidate genes/variants, particularly for those genes with an unanticipated role in addiction. This FOA will utilize the R21 grant mechanism.

On December 21, 2006, NIDA issued a PA entitled Non-Injection Drug Abuse and HIV/AIDS (R21) (PAS-07-262). This FOA seeks to understand the contribution of non-injection drug abuse to the acquisition and/or transmission and/or disease progression of HIV/AIDS through use of the R21 mechanism to support new exploratory and developmental research projects.

On December 21, 2006, NIDA issued a PA entitled Non-Injection Drug Abuse and HIV/AIDS (R03) (PAS-07-261). This FOA seeks to understand the contribution of non-injection drug abuse to the acquisition and/or transmission and/or disease progression of HIV/AIDS through use of the NIH Small Research Grant (R03) award mechanism.

On January 5, 2007, NIDA issued a PA entitled International Research Collaboration on Drug Addiction (R01) (PA-07-275). This PA solicits collaborative research proposals on drug abuse and addiction that take advantage of special opportunities that exist outside the United States. Special opportunities include access to unusual talent, resources, populations, or environmental conditions in other countries that will speed scientific discovery. Projects must have relevance to the mission of NIDA and where feasible should address NIDA's scientific priority areas.

On January 9, 2007, NIDA issued a PA entitled Collaborative Multi-Site Research in Addiction (COMRAD) (R01) (PA-07-286). Through this PA, NIDA seeks to increase the collaboration of investigators at two or more sites in order to address critical issues in the epidemiology, services, and prevention of substance abuse and related disorders that require sample sizes or sample diversity greater than a single site can reasonably attain.

On October 17, 2006, NIDA issued an RFA entitled Development of Immunotherapeutic Products for the Treatment of Methamphetamine Addiction (U01) (RFA-DA-07-004). The objective of this solicitation is to support research in the design, synthesis, and pre-clinical evaluation of vaccines developed from methamphetamine-protein conjugates for the active immunotherapeutic treatment of methamphetamine addiction.

On October 17, 2006, NIDA issued an RFA entitled Design, Synthesis, and Preclinical Testing of Potential Treatment Agents for Drug Addiction (R01) (RFA-DA-07-006). This FOA solicits research applications from institutions/organizations that propose design, synthesis, and preclinical testing of potential treatment agents for drug addiction and/or relapse prevention.

On November 16, 2006, NIDA issued an RFA entitled Brain Imaging Drug Use Prevention Messages (R21) (RFA-DA-07-007). The purpose of this FOA is to stimulate exploratory, i.e., descriptive, hypothesis-generating, research on neurobiological responses to substance abuse prevention media messages in humans using established brain imaging methods. There is particular interest in studies across developmental stages and age groups.

On November 3, 2006, NIDA issued an RFA entitled Extinction and Pharmacotherapies for Drug Addiction (R03) (RFA-DA-07-011). The purpose of this FOA is to stimulate research on the mechanisms underlying extinction in order to guide the development of interventions for enhancing extinction of drug-seeking behavior. This FOA will utilize the R03 grant mechanism.

On November 21, 2006, NIDA issued an RFA entitled Extinction and Pharmacotherapies for Drug Addiction (R01) (RFA-DA-07-010). The purpose of this FOA is to stimulate research on the mechanisms underlying extinction in order to guide the development of interventions for enhancing extinction of drug-seeking behavior. This FOA will utilize the R01 grant mechanism.

On October 12, 2006, NIDA issued a Request for Applications entitled Mechanisms of Drug Abuse Interactions with HIV Neuropathogenesis (R21) RFA-DA-07-003 as well as a Notice of Intent to Publish an R01 Request for Applications to Accompany the Published R01 (NOT-DA-07-001). The receipt date for these applications is March 21, 2007. There is evidence that drug exposure increases the rate and/or severity of HIV-associated neurologic complications. Whether these interactions are mediated by effects on viral entry into the CNS, changes in the neural environment that affect viral replication, chronic processes that contribute to disease progression in the brain, or altered susceptibility of neural cells to damage is unknown. In order to broaden the AIDS research portfolio in both basic and clinical neuroscience, this RFA will encourage a broad range of interdisciplinary basic and/or clinical research approaches to define the basis of interaction between substances of abuse and HIV infection of the brain, including effects on neuropathogenesis and neuropathology.

On November 20, 2006, NIDA issued an RFA entitled Mechanisms of Drug Abuse Interactions with HIV Neuropathogenesis (R01) (RFA-DA-07-002). This FOA solicits research grant applications to examine the mechanisms of interaction between licit or illicit substance abuse, or medications to treat substance abuse, and events related to the etiology and pathogenesis of HIV-associated neurologic complications.

NIDA is the lead institute for a Roadmap Initiative (RFA-RM-07-004) that was released recently entitled, Facilitating Interdisciplinary Research via Methodological and Technological Innovation in the Behavioral and Social Sciences (R21). Dr. Lisa Onken is the NIDA contact for this RFA.

PAs and RFAs with Other NIH Components/Agencies

Bioengineering Research Grants (BRG) (R01) (PA-07-279)

Mechanisms, Models, Measurement and Management in Pain Research (R01) (PA-07-282)

Health Disparities in HIV/AIDS: Focus on African Americans (R21) (PA-07-289)

Health Disparities in HIV/AIDS: Focus on African Americans (R03) (PA-07-290)

Research on Social Work Practice and Concepts in Health (R01) (PA-07-292)

NIH Pathway to Independence (PI) Award (K99/R00) (PA-07-297)

Community Participation in Research (R01) (PAR-07-283)

Research on Ethical Issues in Human Subjects Research (R01) (PA-07-277)

Nanoscience and Nanotechnology in Biology and Medicine (R01) (PAR-07-270)

Nanoscience and Nanotechnology in Biology and Medicine (R21) (PAR-07-271)

Characterization, Behavior and Plasticity of Pluripotent Stem Cells (R01) (PA-07-201)

Decision Making in Health: Behavior Maintenance (R01) (PA-07-204)

Networks and Pathways Collaborative Research Projects (R01) (PA-07-266)

Collaborations with National Centers for Biomedical Computing (R01) (PAR-07-249)

Exploratory Collaborations with National Centers for Biomedical Computing (R21) (PAR-07-250)

Brain Disorders in the Developing World: Research Across the Lifespan (R01) (PAR-07-268)

Interactions Between Stem and Progenitor Cells and the Microenvironment in Vivo (R01) (PAS-07-189)

Non-Human Lentiviral Models of the Neurological Complications of AIDS (R01) (PAS-07-191)

Ruth L. Kirschstein National Research Service Awards for Individual Predoctoral Fellowships (F31) to Promote Diversity in Health-Related Research (PA-07-106)

Ruth L. Kirschstein National Research Service Awards for Individual Predoctoral Fellows (F31) (PA-07-002)

Ruth L. Kirschstein National Research Service Awards (NRSA) for Individual Postdoctoral Fellows (F32) (PA-07-107)

Research on Sleep and Sleep Disorders (PA-07-140)

Understanding Mechanisms of Health Risk Behavior Change in Children and Adolescents (R01) (PA-07-148)

The Science and Ecology of Early Development (SEED) (R01) (PA-07-149)

Health Disparities Among Minority and Underserved Women (R01) (PA-07-154)

The Effect of Racial and Ethnic/Discrimination /Bias on Healthcare Delivery (R01) (PA-07-206)

Research on Pathways Linking Environments, Behaviors and HIV/AIDS (R01) (PAR-07-143)

Tools for Zebrafish Research (R01) (PAR-07-145)

Building Translational Research in Integrative Behavioral Science (R01) (PAR-07-155)

National Cooperative Drug Discovery Groups for the Treatment of Mental Disorders, Drug or Alcohol Addiction (U10) (PAR-07-159)

Innovations in Biomedical Computational Science and Technology Initiative (SBIR [R43/R44]) (PAR-07-160)

Innovations in Biomedical Computational Science and Technology Initiative (STTR [R41/R42]) (PAR-07-161)

Research on Rural Mental Health and Drug Abuse Disorders (R01) (PA-07-103)

Co-Occurring Mental Illness, Alcohol and/or Drug Abuse & Medical Conditions (R01) (PA-07-104)

Psychopharmacology of Widely Available Psychoactive Natural Products (R01) (PA-07-108)

Cross-Disciplinary Translational Research at NIH (R01) (PA-07-109)

Behavioral & Integrative Treatment Development Program (R01) (PA-07-111)

Health Disparities in HIV/AIDS: Focus on African Americans (R01) (PA-07-116)

Health Services Research on the Prevention and Treatment of Drug and Alcohol Abuse (R01) (PA-07-119)

Complementary and Alternative Medicine for Substance Abuse and Alcohol Related Disorders (R01) (PA-07-120)

The Development of Frontal Cortex and Limbic System and Their Roles in Drug Abuse or Mental Health (R01) (PA-07-121)

Economics and Prevention and Treatment Services for Drug and Alcohol Abuse (R01) (PA-07-122)

Non-Injection Drug Abuse and HIV/AIDS (R01) (PAS-07-115)

HIV/AIDS, Severe Mental Illness and Homelessness (R01) (PA-07-090)

Social and Cultural Dimensions of Health (R01) (PA-07-045)

Research on Mind-Body Interactions and Health (R01) (PA-07-046)

Methodology and Measurement in the Behavioral and Social Sciences (R01) (PA-07-060)

Parenting Capacities and Health Outcomes in Youths and Adolescents (R01) (PA-07-061)

Mechanisms of Alcohol and Drug Induced Pancreatitis (R01) (PA-07-067)

Research Project Grant (Parent R01) (PA-07-070)

Molecular Genetics of Drug Addiction and Related Co-Morbidities (R01) (PA-07-073)

Research on the Reduction and Prevention of Suicidality (R01) (PA-07-079)

Women's Mental Health in Pregnancy and the Postpartum Period (R01) (PA-07-081)

Risk Factors for Psychopathology Using Existing Data Sets (R01) (PA-07-082)

Basic and Translational Research in Emotion (R01) (PA-07-083)

Developmental Psychopharmacology (R01) (PA-07-084)

Recent HIV Infection: New Prevention Challenges and Opportunities (R01) (PA-07-087)

Functional Links Between the Immune System, Brain Function and Behavior (R01) (PA-07-088)

HIV Infection of the Central Nervous System (R01) (PA-07-089)

Drug Discovery for Nervous System Disorders (R01) (PA-07-048)

Drug Discovery for Nervous System Disorders (R21) (PA-07-049)

Dissemination and Implementation Research in Health (R01) (PA-07-086)

Senior Scientist Research and Mentorship Award (K05) (PA-06-555)

Women's Interagency HIV Study (WIHS) IV, Limited Competition (U01) (RFA-AI-07-004)

Neuroimaging Informatics Software Enhancement for Improved Interoperability and Dissemination (R03) (RFA-EB-07-002)

The Genes, Environment and Development Initiative (U01) (RFA-DA-07-012)

Joint NIDA-NIJ Initiative for Research on Retail Drug Markets (R21) (RFA-DA-07-013)

Ruth L. Kirschstein National Research Service Awards for Interdisciplinary Individual Postdoctoral Fellows for Training in Neurodegeneration Research (F32) (RFA-AG-07-004)

Short-term Interdisciplinary Career Enhancement Awards for Neurodegeneration Research (K18) (RFA-DC-07-005)

Therapeutics Delivery for Neurodegenerative Diseases (R21) (RFA-EY-07-001) Biomarkers for Neurodegeneration (R21) (RFA-NS-07-004)


In November 2006, NIDA and the Dutch Addiction Program (DAP) announced the availability of administrative supplements in FY07 to support binational collaborative research projects. This program is a continuation of the U.S.-Netherlands Collaborative Research Program on Drug Abuse, using the uniquely successful model of joint funding for binational collaborative research. The joint scientific reviews conducted by the separate U.S. and Dutch funding agencies ensure that each binational research project meets the individual nations' research criteria and priorities; the joint funding permits NIDA and DAP to expand the impact of their scarce financial resources. NIDA provides support to the U.S. researcher and DAP provides support to the Dutch scientist. Letters of intent were due December 15, 2006; applications are due March 26, 2007; and funding will be approved no later than July 2007. The supplement announcement is available at: http://grants.nih.gov/grants/guide/notice-files/NOT-DA-07-003.html.

Other Program Activities

CTN Update

The CCTN received proposals in response to an NIH SBIR Contract Solicitation for the following titles. A review meeting is planned for February or March.

Topic 088, Automation of the Development of Electronic Data Capture System for Clinical Trials Data Collection and Management
Topic 089, Development of Practical Training Materials for Evidence-Based Treatment

A total of 25 protocols have been initiated since 2001. A total of 7,451 participants enrolled in studies as of October 31, 2006. Of these studies, 16 have completed enrollment and locked the data; four completed enrollment and are in the follow-up phase; and five are currently enrolling. Two new protocols are in the development phase.

Primary outcome papers are published and dissemination materials have been developed with CSAT's ATTC on the following:

Protocol CTN 0001, Buprenorphine/Naloxone versus Clonidine for Inpatient Opiate Detoxification
Protocol CTN 0002, Buprenorphine/Naloxone versus Clonidine for Outpatient Opiate Detoxification
Protocol CTN 0005, MI (Motivational Interviewing) To Improve Treatment Engagement and Outcome in Subjects Seeking Treatment for Substance Abuse
Protocol CTN 0006, Motivational Incentives for Enhanced Drug Abuse Recovery: Drug Free Clinics
Protocol CTN 0007, Motivational Incentives for Enhanced Drug Abuse Recovery: Methadone Clinics

Eleven other protocols have locked the data:

Protocol CTN 0003, Bup/Nx: Comparison of Two Taper Schedules
Protocol CTN 0004, MET (Motivational Enhancement Treatment) To Improve Treatment Engagement and Outcome in Subjects Seeking Treatment for Substance Abuse
Protocol CTN 0008, A Baseline for Investigating Diffusion of Innovation
Protocol CTN 0009, Smoking Cessation Treatment with Transdermal Nicotine Replacement Therapy in Substance Abuse Rehabilitation Programs
Protocol CTN 0011, A Feasibility Study of a Telephone Enhancement Procedure (TELE) to Improve Participation in Continuing Care Activities
Protocol CTN 0012, Characteristics of Screening, Evaluation, and Treatment of HIV/AIDS, Hepatitis C Viral Infection, and Sexually Transmitted Infections in Substance Abuse Treatment Programs
Protocol CTN 0016, Patient Feedback: A Performance Improvement Study in Outpatient Addiction Treatment
Protocol CTN 0017, (HIV and HCV Intervention in Drug Treatment Settings).
Protocol CTN 0018, (Reducing HIV/STD Risk Behaviors: A Research Study for Men in Drug Abuse Treatment)
Protocol CTN 0019, (Reducing HIV/STD Risk Behaviors: A Research Study for Women in Drug Abuse Treatment)
Protocol CTN 0021, (Motivational Enhancement Treatment to Improve Treatment Engagement and Outcome for Spanish-Speaking Individuals Seeking Treatment for Substance Abuse). This is the first Spanish-only protocol in the CTN.

Four protocols have ended new enrollment and are in either follow-up or data-lock phase:

Protocol CTN 0010, (Buprenorphine/Naloxone Facilitated Rehabilitation for Opioid Dependent Adolescents/Young Adults) began enrollment in July 2003. Recruitment ended in January 2006.
Protocol CTN 0013, (Motivational Enhancement Therapy to Improve Treatment Utilization and Outcome In Pregnant Substance Abusers) began enrollment in November 2003 and completed recruitment in May 2006 and follow-up in September 2006.
Protocol CTN 0015, (Women's Treatment for Trauma and Substance Use Disorder: A Randomized Clinical Trial) began in March 2004. The study reached its enrollment target in October 2005, and follow-up continues until early 2007.
Protocol CTN 0020, (Job Seekers Training for Substance Abusers). The protocol began enrollment in October 2004 and reached its enrollment target in February 2006. This study is also being conducted in a Navajo American Indian site, the Na'nizhoozhi Center, Inc. in Gallup, New Mexico, the first CTN study to be conducted there. Follow-up is complete at all sites as of December 2006.

Five protocols are currently enrolling:

Protocol CTN 0014, Brief Strategic Family Therapy for Adolescent Drug Abusers (BSFT), has been implemented at eight sites. The study has reached 96% enrollment. There currently are a total of 460 randomized participants.
Protocol CTN 0027, Starting Treatment with Agonist Replacement Therapies (START) is a randomized, open-label, multi-center study that was developed in collaboration with the Division of Pharmacotherapies & Medical Consequences of Drug Abuse (DPMCDA). Enrollment began in April 2006 and includes eight sites. Seven of the sites are actively recruiting. As of October 31, 2006, there were 107 randomized participants.
Protocol CTN 0028, Randomized Controlled Trial of Osmotic-Release Methylphenidate (OROS MPH) for Attention Deficit Hyperactivity Disorder (ADHD) in Adolescents with Substance Use Disorders (SUD). Enrollment is now open at 10 sites. Thirty-six participants have been randomized.
Protocol CTN 0029, A Pilot Study of Osmotic-Release Methylphenidate (OROS MPH) in Initiating and Maintaining Abstinence in Smokers with Attention Deficit Hyperactivity Disorder (ADHD). This study is being carried out at six community treatment sites across five Nodes. There are a total of 116 randomized participants.
Protocol CTN 0030, Prescription Opioid Addiction Treatment Study (POATS) is a randomized 2-phase, open-label, multi-center study in outpatient treatment settings. Pre-screening began in May 2006. The study will be carried out in 11 sites. Forty-three participants have been randomized.

Two protocols are in the development phase:

Protocol CTN 0031, Twelve-Step Facilitation: Evaluation of an Intervention to Improve Substance Abuse Treatment Outcomes by Increasing 12-Step Involvement. This protocol has been presented to the DSMB/Protocol Review Board.
Protocol CTN 0032, HIV Rapid Testing. This protocol is in the early planning stages; the concept was recently approved by the CTN Steering Committee and NIDA and the investigators will begin to develop the protocol.

In addition to the primary CTN trials, there are currently 27 funded studies supported by independent grants that use CTN studies as a platform.

NIDA's New and Competing Continuation Grants Awarded Since September 2006

Anastasio, Noelle C. -- University of Texas Medical Branch Galveston
Role of NMDAR Regulation in Phencyclidine-Induced Neurotoxicity

Anderson, Karen G. -- West Virginia University
Effects of Abused Drugs and Genetics on Impulsive Choice

Ang, Rosalind L. -- Mount Sinai School of Medicine of New York University
Mechanisms of Hallucinogen Specific Neuronal Response

Angstman, Sarah E. -- University of Montana
Tobacco Use Among Alaska Native College Students

Anthony, James C. -- Michigan State University
NIDA Epidemiology Training Program: ICOHRTA

Atkinson, Nigel S. -- University of Texas Austin
Chromatin Remodeling as a Mechanism to Produce Drug Tolerance

Bai, Guang -- University of Maryland Baltimore Professional School
Epigenetic Developmental Effects of Paternal Cocaine Exposure

Baicy, Kate -- University of California Los Angeles
Methamphetamine Dependence and Emotion Regulation

Baldwin, Gayle C. -- University of California Los Angeles
In Vivo Modeling of Methamphetamine and HIV Interactions

Barbarich-Marsteller, Nicole C. -- Associated University-Brookhaven National Laboratory
Neurochemical and Behavioral Alterations in Reward

Barr, Gordon A. -- Hunter College
MIDARP at Hunter College

Belenko, Steven R. -- Treatment Research Institute, Inc. (TRI)
Implementing Evidence-Based Drug Treatment in Criminal Justice Settings

Berg, Karina M. -- Yeshiva University
Improving Measurement of Antiretroviral Adherence in Current and Former Drug User

Bhide, Pradeep G. -- Massachusetts General Hospital
Cocaine and Brain Development

Blackard, Jason T. -- University of Cincinnati
Extrahepatic Replication and Viral Evolution of HCV During HCV/HIV Co-Infection

Blanco, Carlos -- New York State Psychiatric Institute
Substance Abuse In US Hispanics: A National Study

Booth, Brenda M. -- University of Arkansas Medical Sciences Little Rock
The 2006 Addiction Health Services Research Conference

Bornovalova, Marina A. -- University of Maryland College Park Campus
Distress Tolerance Treatment For Inner-City Drug Users

Boyer, Edward W. -- University of Massachusetts Medical School Worcester
Opioids, Internet Pharmacies, Self-Treated Chronic Pain, and HIV/AIDS

Brenner, Sharon L. -- University of Washington
Temperamental and Social Risk For Youth Substance Use

Brisson, Anne E. -- Columbia University Health Sciences
HIV Prevention With Heroin Using Women Sex Workers In Tajikistan

Brody, Gene H. -- University of Georgia
Preventing Substance Use and Risky Behavior Among Rural African American Youth

Bromberg, Jonas -- Inflexxion, Inc.
Improving Pain Management In Cancer Care In Latinos

Brookmeyer, Kathryn A. -- Georgia State University
Disentangling Pathways of Adolescent Sexual Risk from Problem Behavior Syndrome

Brown, Lawrence S. -- Addiction Research and Treatment Corp.
Electronic Information System To Enhance Practice At An Opioid Treatment Program

Brown, Russell W. -- East Tennessee State University
Amphetamine Sensitization In a Model of Schizophrenia

Burdon, William M. -- University of California Los Angeles
Residential Vs. Intensive Outpatient Prison-Based Treatment

Burdzovic Andreas, Jasmina -- Harvard University Medical School
Substance Use In Adolescents from High-Risk Neighborhoods: Risk and Protection

Cain, Mary E. -- Kansas State University
The Amygdala, Individual Differences, and Conditioned Hyperactivity

Caron, Marc G. -- Duke University
Drug Abuse: Discovering Ligands for Pertinent Gpcrs

Carroll, Kathleen M. -- Yale University
Computer-Based Training in Cognitve Behavioral Therapy

Carroll, Marilyn E. -- University of Minnesota Twin Cities
Vulnerability to Drug Abuse and Treatment Efficacy: Animal Models

Catalano, Richard F. -- University of Washington
Reducing Risk & Enhancing Protective Factors In Children

Chandra, Siddharth -- University of Pittsburgh at Pittsburgh
Population-Level Analyses of Multi-Drug Comsumption

Chao, Michael Y. -- California State University San Bernardino
Serotonin and Dopamine Regulation of Behavioral Plasticity In C. Elegans

Chartoff, Elena H. -- McLean Hospital, Belmont, MA
Consequences of Repeated Kappa Receptor Activation on Brain Stimulation Reward

Chavkin, Charles -- University of Washington
Dynorphins and Kappa Opioid Receptors in the Stress Response

Chen, Xiangning -- Virginia Commonwealth University
Genetics of Nicotine and Other Abused Substances

Cherek, Don R. -- University of Texas Health Sciences Center Houston
Drugs of Abuse and Human Aggressive Behavior

Chung, Hwan -- Michigan State University
Model Assessment and Selection for Latent Transition Models

Cochran, Susan D. -- University of California Los Angeles
Drug Use, HIV, and Other Comorbidities In A Vulnerable Population

Cohen, Mark S. -- University of California Los Angeles
Comprehensive Training In Neuroimaging Fundamentals and Applications

Cohen, Mark S. -- University of California Los Angeles
Comprehensive Training in Neuroimaging Fundamentals and Applications

Colder, Craig R. -- State University of New York at Buffalo
Problem Behavior, Peers, and Motivational Aspects of Temperament In Substance Use

Coles, Lisa D. -- University of Maryland Baltimore Professional School
Changes in Brain and Placental Distribution During Pregnancy

Colfax, Grant N. -- Public Health Foundation Enterprises
Aripiprazole Treatment for Methamphetamine Dependence among High-Risk MSM

Comer, Sandra D. -- New York State Psychiatric Institute
Sustained-Release Naltrexone for Opioid Dependence: Longitudinal Study In Humans

Conrad, Kelly L. -- Rosalind Franklin University of Medicine & Science
Cocaine Craving and Receptor Trafficking

Copenhaver, Michael M. -- University of Connecticut Storrs
A Healthy Transition for Newly Released HIV-Infected Prisoners

Copenhaver, Michael M. -- University of Connecticut Storrs
Testing A Community-Friendly Risk Reduction Intervention For Injection Drug Users

Cottler, Linda B. -- Washington University
Indo-US Fogarty Training Program In Behavioral Disorders

Cottler, Linda B. -- Washington University
Prescription Drug Misuse, Abuse and Dependence

Courser, Matthew -- Pacific Institute for Research and Evaluation
The Impact of Active Consent On Student Survey Data

Coviello, Donna M. -- University of Pennsylvania
Employment Intervention For Offenders

Crowley, Thomas J. -- University of Colorado Denver/Health Science Center Aurora
Substance Dependent Adolescents: Imaging Risk-Taking

Damaj, Mohamad Imad -- Virginia Commonwealth University
Role of Calcium-Dependent Mechanisms In Nicotine's Tolerance and Effects

D'aquila, Richard T. -- Vanderbilt University
Vanderbilt Meharry Center for AIDS Research

Dawidowicz, Eliezar A. -- Marine Biological Laboratory
Neural Development and Genetics of Zebrafish

Day, Jeremy J. -- University of North Carolina Chapel Hill
Neural Regulation of Effort In Goal-Directed Behaviors

De Lecea, Luis -- Stanford University
Hypocretin and Drug Addiction

Delbello, Melissa P. -- University of Cincinnati
Topiramate For Co-Occurring Cannabis Use and Bipolar Disorders In Adolescents

Dembo, Richard -- University of South Florida
Brief Intervention for Drug Use and HIV/STD Risk Prevention Among Non-Delinquent Truants

Dewey, William L. -- Virginia Commonwealth University
Training In the Pharmacology of Abused Drugs

Dichter, Marc A. -- University of Pennsylvania
Postdoc Training In Translational Research In Neural Injury and Neurodegeneration

Dickinson, Michael H. -- California Institute of Technology
Crcns: Automated Behavior Analysis for Model Genetic Organism

Dickson-Gomez, Julia B. -- Institute for Community Research
High Risk Crack Use Settings and HIV In El Salvador

Domino, Edward F. -- University of Michigan at Ann Arbor
Effects of Nicotine On Human Cerebral Transmitters

Dracheva, Stella -- Mount Sinai School of Medicine of New York University
Vulnerability to Addiction: A Role For 5-Ht2c Receptor Editing and Expression

Drenan, Ryan M. -- California Institute of Technology
Nicotinic ACh Receptors and Noradrenergic Neurotransmission In Nicotine Addiction

Eby, Lillian T. -- University of Georgia
Clinical Supervision and Turnover In Substance Abuse Treatment

Edwards, Robert H. -- University of California San Francisco
Presynaptic Mechanisms of Neural Plasticity

Eitan, Shoshana -- Texas A&M University System
Functionality of the Opioid System During Adolescent Development Across Genders

Eliassen, James C. -- University of Cincinnati
Linking Serotonin and Memory Functions In MDMA Users By Concurrent EEG and fMRI

Elmer, Gregory I. -- University of Maryland Baltimore Professional School
Algorithm for Drug Discovery

Engle, Bretton C. -- Florida International University
Commitment Language In Adolescent AOD Treatment Groups

Eshleman, Susan H. -- Johns Hopkins University
HIV Prevention Trials Network: Network Laboratory

Evins, A. Eden -- Massachusetts General Hospital
Glycine Transport Inhibition for Nicotine Dependence In Schizophrenia

Fellows, Lesley K. -- McGill University
Orbitofrontal and Striatal Mechanisms In Stress and Addiction

Finkel, Leif H. -- University of Pennsylvania
Integrated Interdisciplinary Training In Computational Neuroscience

Fleming, Thomas R. -- Fred Hutchinson Cancer Research Center
Leadership for HIV/AIDS Clinical Trials Networks: HIV Prevention Trials Network

Fortuna, Lisa R. -- Cambridge Health Alliance
CBT Treatment For PTSD and SUDs In Minority Youth

Fricker, Lloyd D. -- Yeshiva University
Neuropeptides, Processing Enzymes, and Drug Abuse

Furneaux, Henry M. -- University of Connecticut School of Medicine and Dentistry
Cannabinoid Receptor (CNR1) MicroRNAs and Addictive Disease

Garavan, Hugh P. -- Nathan S. Kline Institute for Psychiatric Research
The Role of Executive Functions In Cocaine Abuse

Garris, Paul A. -- Illinois State University
Mechanisms of Amphetamine Action On Dopaminergic Signaling

Glenzer, Vicky Ann -- Oregon Center for Applied Science, Inc.
Interactive Training for Parents of At-Risk Children

Glenzer, Vicky Ann -- Oregon Center for Applied Science, Inc.
Internet Step-parent Training For Parents of Adolescents

Goldowitz, Daniel -- University of Tennessee Health Science Center
Gene To Phenotype Networks For Alcohol & Drug Addiction

Gorbach, Sherwood L. -- Tufts University Boston
HIV Infection In Drug Users In Two International Sites

Graham, Amanda L. -- Society of Behavioral Medicine
Society of Behavioral Medicine Annual Meeting & Scientific Sessions

Greenwald, Mark K. -- Wayne State University
Reducing Cocaine/Heroin Abuse With SR-Amphetamine and Buprenorphine

Grodzicker, Terri I. -- Cold Spring Harbor Laboratory
CSHL Conference On Channels, Receptors, Synapses

Gu, Howard H. -- Ohio State University
Cocaine and Monoamine Transporters

Gustafson, David H. -- University of Wisconsin Madison
RCT Evaluating Improvement Strategies for Addiction Treatment

Hall, Edward D. -- University of Kentucky
Therapeutic Strategies for Neurodegeneration Training Grant

Harris, Kathleen Mullan -- University of North Carolina Chapel Hill
The National Longitudinal Study of Adolescent Health

Hawrot, Edward -- Brown University
Role of Alpha3-Containing Nicotinic Receptors In Mediating Central Nicotine Effects

Hawrot, Edward -- Brown University
The Neuronal Nicotinic Acetylcholine Receptor Interactome Via A Knock-In Mouse

He, Johnny J. -- Indiana University-Purdue University at Indianapolis
Use A Novel Tat Transgenic Model To Develop Neuroaids Therapeutics

Heatherton, Todd F. -- Dartmouth College
Effects of Social Context On The Neural Correlates of Cue Reactivity

Henggeler, Scott W. -- Medical University of South Carolina
Vocational Outcomes For Youth With Substance Abuse Problems and High HIV Risk

Heninger, George R. -- Yale University
Substance Abuse Education for Medical Students

Hinds, Bruce J. -- University of Kentucky
Gated Carbon Nanotube Membrane Transdermal Drug Delivery

Hogle, Joanne M. -- University of Wisconsin Madison
Sex Differences In the Effect of Smoking Withdrawal on Emotion Response

Hohmann, Andrea G. -- University of Georgia
Endocannabinoid Analgesia: An In Vivo Gene Transfer - Lipidomics Approach

Hoshino, Yoshihiko -- New York University School of Medicine
RNAS Editing and Its Inhibition Of HIV-1 Replication In Human Macrophage

Howe, Chanelle J. -- Johns Hopkins University
Methods For Informative Censoring HIV/AIDS Cohorts

Howell, Leonard L. -- Emory University
PET Imaging and Cocaine Neuropharmacology In Monkeys

Huang, Yiyun -- Yale University
New PET Radioligand For the Serotonin Transporter

Hubert, George W. -- Emory University
Anatomy and Activation of Nucleus Accumbens CART Neurons

Hurt, Richard D. -- Mayo Clinic College of Medicine, Rochester
Efficacy of Methylphenidate For Treating Tobacco Dependence

Inciardi, James A. -- University of Delaware
Case Management Alternatives for African American Women At High Risk For HIV

Jackson-Newsom, Julia -- Tanglewood Research, Inc.
Drug Prevention for Children In After-School and Community Settings

Jacobs, Russell E. -- California Institute of Technology
In Vivo Detection of Neuronal Activity

Janowsky, Aaron J. -- Oregon Health & Science University
Methamphetamine Abuse Research Center

Jarcho, Johanna M. -- University of California Los Angeles
Dopamine's Role In Pain Sensivity & Placebo Analgesia

Kadden, Ronald M. -- University of Connecticut School of Medicine and Dentistry
Contingency Management for Marijuana Dependence

Kaestner, Klaus H. -- University of Pennsylvania
Development of C57bl/6 Es Cell Technology For High Thoughput Use

Kass, Robert E. -- Carnegie-Mellon University
Interdisciplinary Training In Computational Neuroscience

Kessler, John A. -- Northwestern University
Training For A New Interdisciplinary Research Workforce In Regenerative Medicine

Kim, Seong-Gi -- University of Pittsburgh at Pittsburgh
Multimodal Neuroimaging Training Program

Kirby, Lynn G. -- Temple University
Regulation of Serotonin Circuits In Opiate Addiction and Relapse

Knackstedt, Lori A. -- Medical University of South Carolina
Evaluating Models of Cocaine Self-Administration

Knowlton, Amy R. -- Johns Hopkins University
Informal Caregiving & Medical Adherence Among HIV+ IDUs

Knuepfer, Mark M. -- Saint Louis University
Effects of Chronic Stress Or Psychostimulants On CNS and ANS

Koodie, Lisa -- University of Minnesota Twin Cities
Morphine Induced Modulation of Tumor Growth

Kosterman, Richard -- University of Washington
Social Development and Psychopathology Into Adulthood

Kral, Alexander H. -- Research Triangle Institute
Correlates of Sexual Risk For HIV/STI Among Women Who Use Methamphetamine

Kushel, Margot B. -- University of California San Francisco
Pain and Misuse of Prescription Opioids In A Community-Based HIV-Infected Cohort

Labrie, Richard A. -- Cambridge Health Alliance
An Assessment of A Problem Gambling Self-Change Toolkit

Lahvis, Garet P. -- University of Wisconsin Madison
Social Approach Behaviors and Reward Pathways of Adolescent Mice

Lau, Elaine K. -- University of California San Francisco
Morphine-Regulated Phosphorylation of Opioid Receptors

Lee, Yue-Wei (David) -- McLean Hospital, Belmont, MA
Pharmacology and Metabolism Of Salvia Divinorum

Lee, Yun J. -- Women and Infants Hospital-Rhode Island
Massage for Methadone Exposed Infants

Levin, Frances R. -- New York State Psychiatric Institute
Combined Pharmacotherapies for Cocaine Dependence

Li, Chiang-Shan R. -- Yale University
Imaging Inhibitory Control In Cocaine Dependence

Liao, Dezhi -- University of Minnesota Twin Cities
Opioid Receptors In Excitatory Synapses

Lillie-Blanton, Marsha D. -- George Washington University
HIV/AIDS & Women of Color: Roles of Drug Use, Violence & Insurance In HAART Use

Lindsey, Kimberly P. -- McLean Hospital, Belmont, MA
Pharmacologic MRI of Smoked Tobacco: Effects of Abstinence and Dependence

Listman, Jennifer B. -- New York University
Population Genetics & Drug Dependence In Asian Isolates

Liu, Hongjie -- Wayne State University
A Pilot Study of School-Based HIV Intervention In China

Locey, Matthew L. -- University of Florida
Nicotine and the Behavioral Mechanisms of Impulsivity

London, Edythe D. -- University of California Los Angeles
Methamphetamine Abuse, Inhibitory Control: Implications for Treatment

Low, Walter C. -- University of Minnesota Twin Cities
Translational Research In Neurobiology of Disease Training Program

Lute, Brandon J. -- Vanderbilt University
Amphetamine Regulation of the Dopamine Transporter

Mahler, Stephen V. -- University of Michigan at Ann Arbor
Opioid Modulation of Cue-Triggered 'Wanting' In Amygdala

Malison, Robert T. -- Yale University
Genetics of Opioid Dependence In A Hmong (Thai) Isolate

Malow, Robert M. -- Florida International University
Multi-Level HIV Prevention for Pregnant Drug Abusers

Mao, Jianren -- Massachusetts General Hospital
Opioid-Induced Pain Sensitivity: Clinical Diagnosis and Management

Marcus, Bess H. -- Miriam Hospital
Using A YMCA Exercise Program To Enhance Nicotine Dependence Treatment For Women

Margiotta, Joseph F. -- Medical University of Ohio at Toledo
Altering Gene Expression and Function At Single Neuronal Nicotinic Synapses

Marians, Kenneth J. -- Sloan-Kettering Institute for Cancer Research
Integrated PhD Training Program In Cancer Biology

Marinelli, Michela -- Rosalind Franklin University of Medicine & Science
Adolescent Cocaine Abuse: Electrophysiology & Behavior

Marnett, Lawrence J. -- Vanderbilt University
Integrative Training In Therapeutic Discovery

Marota, John J. -- Massachusetts General Hospital
Effects of Cocaine Self-Administration: fMRI of Awake Non-Human Primates

Marsch, Lisa A. -- National Development & Research Institutes
Computer-Delivery of Effective, Psychosocial Interventions In Methadone

Treatment

Martin, Thomas J. -- Wake Forest University Health Sciences
Role of the Amygdala In Opioid Self-Administration In Rats With Chronic Pain

Martinez, Charles R. -- Oregon Social Learning Center, Inc.
A Culturally Specific Intervention for Latino Families

Marzluff, William F. -- University of North Carolina Chapel Hill
UNC-Chapel Hill Integrated Biomedical Research Training Program

Masson, Carmen L. -- University of California San Francisco
Hepatitis Care Coordination In Methadone Treatment

Mathew, Rano T. -- Coastal Horizons Center, Inc.
Improving Co-Occurring Disorder Care in Rural Areas Via Technology Enhancements

May, James C. -- Richmond Behavioral Health Authority
Organizational Factors Influencing Practice Improvement In Community-Based Care

Mayford, Mark R. -- Scripps Research Institute
CBP Acetyltransferase Function In Addictive Behavior

Mcginn, Thomas G. -- Mount Sinai School of Medicine of New York University
Prevention of Depression In HIV/HCV Co-Infected Substance Abuse Patients

Mcginnis, Marilyn Y. -- University of Texas San Antonio
Anabolic Androgenic Steroid Effects on Brain and Behavior

Mckay, James R. -- University of Pennsylvania
Effectiveness of Extended Treatments for Drug Dependence

Mcmanus, Michael T. -- University of California San Francisco
The Epigenetics of Small RNAs In the Mammalian Brain

Muehlbach, Britta -- Daytop Village
Technology Transfer: Promoting Change In The Therapeutic Community

Nagy, Andras -- Mt. Sinai Hospital-Samuel Lunenfeld Research Institute
Contribution to the Completion of Comprehensive Mouse Knockout Resource

Nair, Madhavan P. -- State University of New York at Buffalo
Immunopathogenesis of HIV-1 Infection: Role of Methamphetamine

Naleid, Amy M. -- University of Washington
VTA Opioid, GABA, and Insulin Effects on Sucrose Reward

Nelson, Christopher L. -- Rosalind Franklin University of Medicine & Science
Cellular Plasticity Following Repeated Amphetamine

Nemes, Susanna -- Social Solutions International
Buprenorphine

Nielsen, David A. -- Rockefeller University
DNA Methylation of Promoter CPG Dinucleotides In Opiate Addiction

Nunes, Edward V. -- New York State Psychiatric Institute
Opiate Dependence: Combined Naltrexone/Behavior Therapy

Ochsner, Kevin N. -- Columbia University New York Morningside
The Neural Bases of Affect Regulation in Drug Abuse

Oliveto Beaudoin, Alison -- University of Arkansas Medical Sciences Little Rock
Disulfiram for Cocaine Abuse In Methadone Patients

Ossipov, Michael H. -- University of Arizona
Proteasome Inhibitors: Therapeutics for Pain

Ouellet, Lawrence J. -- University of Illinois at Chicago
Psychiatric Disorders and HIV Risk Behaviors Among Young Injection Drug Users

Palmer, Abraham A. -- University of Chicago
Mouse QTL and Human Association Study of Methamphetamine Sensitivity

Palzkill, Timothy G. -- Baylor College of Medicine
Training In Biomedical Discovery from Large Scale Data Sets

Pantin, Debra Cherry-Ann -- Palladia, Inc.
Developing A CQI Intervention To Implement EBP Within A CBO

Patterson, Thomas L. -- University of California San Diego
Behavior Change and Maintenance Intervention for HIV+ MSM Methamphetamine Users

Paul, Robert H. -- University of Missouri-St. Louis
Functional Neuroimaging of Cognitive Dysfunction In HIV-HCV Co-Infection

Paulson, Autumn M. -- University of Maryland College Park Campus
Anxiety Vulnerabilities In Heroin Users

Pauly, James R. -- University of Kentucky
Prenatal Nicotine, Behavioral Teratogenicity and Dopamine

Pearlson, Godfrey D. -- Yale University
Reward, Impulsivity and Cocaine Addiction: fMRI Studies

Pearson, Zsuzsanna S. -- New York University School of Medicine
Modulation of Dopamine Release By CB1 Receptors

Perkins, Kenneth A. -- University of Pittsburgh at Pittsburgh
Tobacco Smoking, Nicotine and Negative Affect Relief

Perlman, David C. -- Beth Israel Medical Center, New York
Hepatitis Care Coordination In Methadone Treatment

Perron, Brian E. -- Washington University
Psychiatric Comorbidities and Outpatient Substance Abuse Treatment Retention

Perry, Jennifer L. -- University of Minnesota Twin Cities
Impulsivity and Drug Abuse: Sex and Hormonal Effects

Pinto, Elsa -- Florida International University
Dietary Patterns and Drug Use Among Latinas

Piomelli, Daniele -- University of California Irvine
Role of Endocannabinoids In the Behavioral Consequences of Social Isolation

Plant, Tony M. -- University of Pittsburgh at Pittsburgh
International Congress of Neuroendocrinology (ICN 2006)

Pouget, Alexandre -- University of Rochester
CRCNs: Bayesian Decision Making With Probabilistic Population Codes

Quintero, Gilbert A. -- University of New Mexico Albuquerque
Prescription Drug Abuse: The Role of the Internet

Raehal, Kirsten M. -- Ohio State University
Opioid-Induced Somatic Effects In Betaarrestin2-Ko Mice

Ramo, Danielle E. -- University of California San Diego
Developmental Models of Drug Abuse Relapse

Reith, Maarten E. -- New York University School of Medicine
The Dopamine Transporter and Ions, Substrates, Blockers

Reith, Maarten E. -- New York University School of Medicine
Dopamine Transporters: Mechanisms of Ligand Interaction

Reynolds, Jessica L. -- State University of New York at Buffalo
Mechanisms of Cocaine-Induced HIV-1 Infection In NHA

Rigotti, Nancy A. -- Massachusetts General Hospital
Bupropion for Smoking Cessation In Postpartum Women

Roe, Anna W. -- Vanderbilt University
Fast Optical Imaging of Cortical Signals In the Behaving Primate

Roget, Nancy A. -- University of Nevada Reno
NIDA Enters College: Infusing The Science of Addiction Into University Curricula

Rogge, George A. -- Emory University
Regulation of The CART Gene By Promoter CIS-Elements

Rosen, Bruce R. -- Massachusetts General Hospital
Advanced Multimodal Neuroimaging Training Grant

Rosenblum, Andrew Bruce -- National Development & Research Institutes
Sublingual Buprenorphine for Chronic Pain In Patients at Risk for Drug Abuse

Rosengard, Cynthia -- Rhode Island Hospital, Providence, RI
Partner-Specific HIV Risk Reduction for Drug Using Incarcerated Adolescents

Roth, Michael D. -- University of California Los Angeles
Effects of Marijuana on HIV and Viral Immunity

Rowland, Neil E. -- University of Florida
Cue Dependency With Intravenous Nutrients and Nicotine

Royal, Walter -- University of Maryland Baltimore Professional School
Opoid and Retinoid Interactions In the HIV-1 Transgenic Rat

Sadee, Wolfgang -- Ohio State University
Genetic and Epigenetic Regulation of Addiction Genes

Salom, David -- Novasite Pharmaceuticals, Inc.
Crystallization of the Human Cannabinoid Type 2 Receptor

Samet, Jeffrey H. -- Boston Medical Center
Clinical Addiction Research and Education (CARE) Program

Schacht, Joseph P. -- University of Colorado at Boulder
A Transdisciplinary Approach to Cannabis Addiction

Schank, Jesse R. -- Emory University
Dopamine Beta-Hydroxylase and Responses to Cocaine

Schramm-Sapyta, Nicole L. -- Duke University
Role of HPA Axis In Adolescent Vulnerability to Drug Addiction

Schwartz, Philip H. -- Children's Hospital of Orange County
Choc Human Embryonic Stem Cell Culture Training Course

Scott, David J. -- University of Michigan at Ann Arbor
Brain Reward Circuitry and Substance Use Risk

See, Ronald E. -- Medical University of South Carolina
Translational Research in Addiction Center

Shiffman, Saul -- University of Pittsburgh at Pittsburgh
Understanding Emerging Patterns of Non-Daily Smoking: Field and Lab Assessments

Simen, Arthur A. -- Yale University
Epigenetic Factors In Stress-Enhanced Acquisition of Cocaine Self-Administration.

Slesnick, Natasha -- Ohio State University
Evaluation of Treatments For Homeless Youth: CRA, MET and Case Management

Snedker, Karen A. -- University of Washington
The Impact of Neighborhood Context on Substance Abuse

Sofuoglu, Mehmet -- Yale University
GABA Medications for Tobacco Addiction

Sokhadze, Estate M. -- University of Louisville
Emotional and Attentional Biases to Drug and Trauma Cues In Addiction With PTSD

Sombers, Leslie A. -- University of North Carolina Chapel Hill
Functional Analysis of the Mesolimbic Dopamine System

Sood, Amit -- Mayo Clinic College of Medicine, Rochester
Gabapentin for Smoking Abstinence

Sorensen, James L. -- University of California San Francisco
Daart+ As A Structural HIV Intervention In Methadone Maintenance

Sorg, Barbara A. -- Washington State University
Cocaine, Electroconvulsive Seizure and Neural Plasticity

Spiess, Joachim -- University of Hawaii at Manoa
Emotion and Cognition On Gene, Cell, and Systems Levels

Stahl, Philip D. -- Washington University
21st-Century Imaging Sciences: Undergraduate and Graduate Student Training

Stefansson, Kari -- Decode Genetics, Inc.
Genes Contributing To Opioid Abuse In Humans

Stein, Michael D. -- Rhode Island Hospital, Providence, RI
Antidepressants During Office-Based Buprenorphine

Steinberg, Laurence -- Temple University
Peer Effects on Neural and Behavioral Markers of Risk-Taking

Stella, Nephi -- University of Washington
Novel Monoacylglycerol Lipase

Stenger, Victor A. -- University of Hawaii at Manoa
Parallel MRI for Substance Abuse Research

Stone, Laura S. -- University of Minnesota Twin Cities
Proteomic Studies of Human Chronic Pain

Strain, Eric C. -- Johns Hopkins University
Evaluation of Opioid Antagonist Activity In Humans

Sullivan, Mark D. -- University of Washington
Risks for Opioid Use and Abuse In Contrasting Chronic Pain Populations

Sun, Yi E. -- University of California Los Angeles
Epigenetic Gene Regulation In Morphin Addiction

Swanstrom, Ronald I. -- University of North Carolina Chapel Hill
UNC Center For AIDS Research

Szczytkowski-Thomson, Jennifer -- University of North Carolina Chapel Hill
Conditioned Effects of Heroin on Nitric Oxide

Tank, Arnold W. -- University of Rochester
Nicotine Effects on the Adrenal Medulla and Brain

Tank, David W. -- Princeton University
Training Program In Quantitative and Computational Neuroscience

Teplin, Linda A. -- Northwestern University
Drug Use, Disorder & HIV/AIDS Risk In Juvenile Justice Youth:A Longitudinal Study

Thompson, Alexis C. -- State University of New York at Buffalo
Evaluation of Neuropeptide Y As A Target for Cocaine-Dependence Treatment

Todorov, Alexandre A. -- Washington University
Genetic Epidemiology of Opioid Dependence In Bulgaria

Tranel, Daniel T. -- University of Iowa
Drug Abuse, Social Decision-Making, and Sex-Related Functional Brain Asymmetry

Troncale, Joseph A. -- Caron Foundation
Integrated Behavioral Program For Prescription Opiate Addiction and Chronic Pain

Tucker, Jalie A. -- University of Alabama at Birmingham
Telehealth Assessment of Risk Behaviors In Rural HIV+ Substance Users

Ulinski, Philip S. -- University of Chicago
Undergraduate Training In Computational Neuroscience

Umbricht, Annie -- Johns Hopkins University
Clinical Trial of Topiramate For Cocaine Addiction

Uteshev-Gaard, Victor V. -- Southern Illinois University Carbondale
Studying Nicotinic AChrs In Histaminergic Neurons

Valenzuela, David M. -- Regeneron Pharmaceuticals, Inc.
Production of Targeted Null Mutations For 10,000 Genes In C57bl/6 Es Cells

Vermund, Sten H. -- Family Health International
HIV Prevention Trials Network (HPTN) Coordinating and Operations Center

Volsky, David J. -- St. Luke's-Roosevelt Institute for Health Sciences
Effect of Morphine on HIV-1 Neuroinvasion and Brain Changes In Mice

Von Korff, Michael R. -- Center for Health Studies
Long-Term Opioid Management of Chronic Pain: Trends and Risks

Von Zastrow, Mark E. -- University of California San Francisco
Mechanisms Regulating Endocytosis of Opioid Receptors

Walsh, Sharon L. -- University of Kentucky
Evaluation of Atomoxetine for Cocaine Dependence: A Pilot Trial

Wang, Shaomeng -- University of Michigan at Ann Arbor
Design, Synthesis and Characterization Of Dopamine Receptor 3 Ligands

Watkins, Katherine E. -- Rand Corporation
Group CBT For Depression and AOD Disorders

Welch, Sandra P. -- Virginia Commonwealth University
Modulation of Opioid Antinociception and Tolerance By Sphingosine-1-Phosphate

Wells, Rebecca S. -- University of North Carolina Chapel Hill
How Child Welfare Inter-Agency Cooperation May Reduce Youth HIV Risk Behaviors

West, Anne Elizabeth -- Duke University
Epigenetic Regulation of Transcriptional Repression By Drugs of Abuse

West, Mark O. -- Rutgers, The State University of New Jersey, New Brunswick
Cue-Induced Relapse to Cocaine Seeking: Neuronal Activity In Accumbens Circuits

Westmaas, Johann L. -- State University New York Stony Brook
Gender, Social Support, and Stress Reactions In Smokers

Wilens, Timothy E. -- Massachusetts General Hospital
Juvenile Bipolar Disorder and Substance Abuse

Williams, Jason M. -- Vanderbilt University
Insulin Regulation of Amphetamine Action

Wirtshafter, David -- University of Illinois at Chicago
Lateral Hypothalamus, Dopamine and Ingestive Behavior

Wong, Dean F. -- Johns Hopkins University
Training for Clinician Scientists In Imaging Research

Woody, George E. -- University of Pennsylvania
Methadone Maintenance and HIV Risk In Ukraine

Wu, Z. Helen -- University of Texas Medical Branch Galveston
Does Stress Influence Drug Use In Young, Poor Women?

Xu, Jiansong -- University of California Los Angeles
Cigarette Smoking and the Efficiency of the Frontoparietal Attentional Network

Yoburn, Byron C. -- St. John's University
Prescription Opioid Agonists: Tolerance and Efficacy

Zhan, Chang-Guo -- University of Kentucky
Redesign of Butyrylcholinesterase for Cocaine Metabolism

Zhuang, Xiaoxi -- University of Chicago
Epigenetic Mechanisms In Motor Habits Stability

Zubieta, Jon-Kar -- University of Michigan at Ann Arbor
Neurochemistry of Opiate Abuse Risk In Chronic Pain

Zucker, Robert A. -- University of Michigan at Ann Arbor
International Substance Abuse Research Training Program


Index

Research Findings

Program Activities

Extramural Policy and Review Activities

Congressional Affairs

International Activities

Meetings and Conferences

Media and Education Activities

Planned Meetings

Publications

Staff Highlights

Grantee Honors



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